TPK

The initials TPK may refer to:
 * Tai Ping Koon Restaurant
 * Te Puni Kōkiri, the Ministry of Māori Development, New Zealand
 * Total party kill in role-playing games
 * Turun Pallokerho, football club in Turku, Finland
 * TPK algorithm, a simple program introduced by Luis Trabb Pardo and Donald Knuth, to compare early programming languages
 * Traditional Phenological Knowledge