TRNA (guanine37-N1)-methyltransferase

tRNA (guanine37-N1)-methyltransferase (, TrmD, tRNA (m1G37) methyltransferase, transfer RNA (m1G37) methyltransferase, Trm5p, TRMT5, tRNA-(N1G37) methyltransferase, MJ0883 (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine37-N1)-methyltransferase. This enzyme catalyses the following chemical reaction


 * S-adenosyl-L-methionine + guanine37 in tRNA $$\rightleftharpoons$$ S-adenosyl-L-homocysteine + N1-methylguanine37 in tRNA

This enzyme is important for the maintenance of the correct reading frame during translation.