TRNA (guanine6-N2)-methyltransferase

TRNA (guanine6-N2)-methyltransferase (, methyltransferase Trm14, m2G6 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine6-N2)-methyltransferase. This enzyme catalyses the following chemical reaction


 * S-adenosyl-L-methionine + guanine6 in tRNA $$\rightleftharpoons$$ S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA

The enzyme specifically methylates guanine6 at N2 in tRNA.