TTSS

The abbreviation TTSS may refer to:


 * Tinker, Tailor, Soldier, Spy, a novel by John le Carré
 * Tinker Tailor Soldier Spy (miniseries), a 1979 miniseries based on the novel
 * Tinker Tailor Soldier Spy (film), a 2011 film based on the novel
 * Type three secretion system, a protein appendage found in several gram-negative bacteria