Talk:(Human) Mycobiome

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Assignment #5 : Final Article.

Commentary on the peer review:

I had not yet found a way to incorporate the lists into a table.

The word count does reach the allotted 300 word limit, due to the list of fungal biota, but if I were allowed a higher word count then it is indeed a great suggestion to add in human diseases due to (issues with/caused by) the mycobiome. In the case that the list does not count towards the word count, I have added some information on such things.

Lastly, my sources were not all from 2017. They were retrieved in October of 2017, but some sources are from 2010, 2011, 2015, etc.. Overall, thank you for your supportive comments and constructive criticisms.

Original: Mycobiome

The mycobiome consists of the fungal biota in an organism.[1][2][3] It can be affected by conditions such as human obesity.[4]

References 1.	Jump up^ Cui L, Morris A, Ghedin E (July 2013). "The human mycobiome in health and disease". Genome Med. 5 (7): 63. PMC 3978422 . PMID 23899327. doi:10.1186/gm467. Figure 2: Distribution of fungal genera in different body sites 2.	Jump up^ Mahmoud Ghannoum (February 1, 2016). "The Mycobiome". The Scientist (magazine). Retrieved February 5, 2016. 3.	Jump up^ Suhr MJ, Hallen-Adams HE (2015). "The human gut mycobiome: pitfalls and potentials--a mycologist's perspective". Mycologia. 107 (6): 1057–73. PMID 26354806. doi:10.3852/15-147. 4.	Jump up^ Mar Rodríguez, M.; Pérez, Daniel; Javier Chaves, Felipe; Esteve, Eduardo; Marin-Garcia, Pablo; Xifra, Gemma; Vendrell, Joan; Jové, Mariona; Pamplona, Reinald; Ricart, Wifredo; Portero-Otin, Manuel; Chacón, Matilde R.; Fernández Real, José Manuel (2015). "Obesity changes the human gut mycobiome". Scientific Reports. 5: 14600. Bibcode:2015NatSR...514600M. PMC 4600977 . PMID 26455903. doi:10.1038/srep14600.

Edit – Mycobiome

The mycobiome consists of the fungal biota in an organism.[1][2][3] It can be affected by conditions such as human obesity.[4]

The fungal biota can be present in as low as ≤0.1% of the total human microbiota/microbiome. And it is uncertain how the fungal biota interact with the nonfungal constituents of the microbiome. Overall, there is a low abundance of fungi in most biological specimens. The mycobiome is relevant to human physiology as fungi may be important in maintaining microbial community structure, metabolic function, and immune-priming. Mutualism between humans and fungi is not yet well understood.

Human Diseases Some human diseases have been associated with changes in the human mycobiome. These diseases can include Hepatitis, Cystic fibrosis, and Inflammatory bowel disease.

Fungal Biota Present This is not an exhaustive list. Samples collected may have faced issues with sequencing of fungal sequences due to possible cell contamination.

Vaginal Mycobiome

-	Candida (16 taxonomic units) -	Ascomycota -	Saccharomycetales -	Ascomycota Davidiellaceae -	Cladosporium -	Eurotium -	Alternaria -	Basidomycota Rhodotorula,

Intestinal Mycobiome

-	Saccharomyces -	Candida -	Cladosporium -	Agaricus -	S. boulardii

(Infant) Intestinal Mycobiome

-	Saccharomycetales (infant) -	Cladosporium -	Cryptococcus -	Saccharomyces cerevisiae -	Malasseziales -	Eurotiales -	Botryosphaeriales -	Filobasidiales  Oral Mycobiome

-	Candida -	Saccharomyces -	Penicillium -	Aspergillus -	Scopulariopsis -	Genotrichum, , , -	Cryptococcus -	Histoplasma -	Mucor -	Cladosporium -	Fusarium -	Alternaria -	Malassezia -	Epicoccum -	Aureobasidium -	Irpex, -	Cytospora -	Lenziles -	Sporobolomyces -	Dothioraceae -	Teratosphaeria -	Glomus , -	Pichia

Lung Mycobiome

-	Aspergillus -	Penicillium -	Davidiellaceae -	Candida

KaileeWark (talk) 08:03, 20 November 2017 (UTC)

Wiki Assignment #2 – Mycobiome

https://en.wikipedia.org/wiki/Mycobiome

I have chosen the article “Mycobiome” because despite many of the journal articles stating that it is under researched and forgotten (https://www.ncbi.nlm.nih.gov/pubmed/28430946 ), the topic of the (human) mycobiome has high notability. With only an initial Google search, there are several papers published on the mycobiome, such as the mycobiome’s relevance to human physiology (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448585/) (see more links below). When looking at the “Talk” page, this article is also within the scope of three WikiProjects (Microbiology, Medicine, and Fungi) thus the completion of this article would be of benefit to several audiences. This article is also massively lacking in material – there is only one phrase describing the mycobiome, as so there is a lot of room for improvement and to add in information. The topic of fungi’s respiration in the mycobiome will also be strongly linked with MICB 301 class discussions on the topic of different types of respiration and symbiotic and competitive habitation of a certain niche/environment (ie. human skin, gut, etc. mycobiome). I will therefore be adding in a lot of information about the mycobiome’s bioprocesses. I will also be discussing pertinent information that is available (from reliable sources), covering topics of what the community knows relating to the mycobiome.

sources: https://www.ncbi.nlm.nih.gov/pubmed/26354806 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448585/ https://www.ncbi.nlm.nih.gov/pubmed/28430946 http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1000713 http://www.tandfonline.com/doi/full/10.1080/21505594.2017.1279780 http://mbio.asm.org/content/7/5/e01250-16 https://genomemedicine.biomedcentral.com/articles/10.1186/gm467

KaileeWark (talk) 20:09, 27 September 2017 (UTC)

Wikipedia Article Critique

Article: Chlorosome

Although the article “Chlorosome” begins to give the audience a perception of what a chlorosome is, the article does not adequately explain the chlorosome, nor meets the criteria to be a quality Wikipedia article. The references the author used, although primary sources, are quite old (10-15 years old). The article should be based on newer data and more sources. Even with the sources currently used, it is important for this Wikipedia article to integrate more citations into the paragraphs to conform with Wikipedia’s citation rules. The article’s sections need vast improvement, for instance a lot of the introductory paragraph contains information which should be part of the “structure” paragraph. An image to accompany the “structure” paragraph would also be valuable to the article. The section on “Organization of the light harvesting pigments” also explains one research paper in too much detail, over-representing one experiment’s methods. Additionally, a “function” paragraph should be added to this article. The function of the chlorosome would answer questions that the audience is likely searching for when viewing this article. Finally, the section “an alternative energy source” not only needs a reference, but the addition of more current and applicable research on the subject such as “Study of Protein Production…” (2010), would enhance the section. Despite this article’s flaws, there are a few things done well; the article remains unbiased, the material is on topic, and the 4 references that are cited are indeed primary sources and do check out. Overall, the biggest things this article needs to improve on are its sectioning and its citations.

KaileeWark (talk) 04:20, 18 September 2017 (UTC)

KaileeWark's Peer Review
The edit made does a good job on expanding on the sparse information (2 sentences) present in the original article and does so in a coherent, easy to follow manner. The content added is relevant, and focuses primarily on the human mycobiome. This is an interesting approach to take and is likely due to the abundance of recent articles discussing the human mycobiome. Furthermore, the structure flows reasonably well as subsequent sentences continue to discuss the human mycobiome by expanding on previous ideas using appropriate evidence and citations. An example of this is the discussion of the roles of fungi in humans near the end of the first paragraph. In addition, the references used are applicable as they are all primary resources which are all very recent (all are from 2017). This is a good indication that the information is up to date with recent findings. Additionally, the sources used clearly support the statements made in the edit.

Although the edit does a decent job on expanding on the very limited original article, there is area for expansion on some ideas. For example, the list of organisms at the end of the article could be instead incorporated into a table with appropriate hyperlinks added. This will result in a clearer structure which allows for expansion on other notable topics. This is crucial as the original article itself only contains 2 sentences, and hence, it is vital that the word count is used to expand on some of the topics briefly discussed. As an example, the role of the mycobiome in humans can be expanding on by discussing the diseases they may be a part of. Evidence of this can be seen in multiple papers in which the human mycobiome is found to be a factor in diseases such as hepatitis, cystic fibrosis, and inflammatory bowel disease (IBD). Additionally, applicable organisms from the list at the end of the article can then be used as examples of fungi which take part in such diseases and can provide a good example of the specific organisms behind some diseases.

Milad5858 (talk) 06:37, 8 November 2017 (UTC)