Talk:2,6-Xylidine

Inconsistant data on melting point.
This page has an mp of ~11.4. The generalized xylidine has an mp of 8.4 for the 2,6 isomer.

unsourced
moved here per WP:PRESERVE. Per WP:BURDEN please do not restore without finding reliable sources, checking the content against them, and citing them.

2,6-Xylidine is used in the production of a slew of pharmaceutical drugs. For Example: A lot of these can be grouped as local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.
 * Drug uses
 * 1) Droxicainide
 * 2) Etidocaine
 * 3) Lidamidine
 * 4) Lidocaine (Lignocaine)
 * 5) Lidofenin
 * 6) Lidoflazine
 * 7) Nefiracetam
 * 8) Pincainide
 * 9) Ranolazine
 * 10) Tocainide
 * 11) Mepivacaine
 * 12) Bupivacaine
 * 13) Ropivacaine

-- Jytdog (talk) 20:37, 11 April 2017 (UTC)

unsourced 2
moved here per PRESERVE

2,6-Xylidine is used in the production of some pharmaceutical drugs, including:
 * Drug uses


 * 1) Ameltolide
 * 2) Bupivacaine
 * 3) Butanilicaine
 * 4) Droxicainide
 * 5) Etidocaine
 * 6) Lidamidine
 * 7) Lidocaine (Lignocaine)
 * 8) Lidofenin
 * 9) Lidoflazine
 * 10) Mepivacaine
 * 11) Nefiracetam
 * 12) Neraminol
 * 13) Pilsicainide
 * 14) Pincainide
 * 15) Pyrrocaine
 * 16) Ralitoline
 * 17) Ranolazine
 * 18) Recainam
 * 19) Rodocaine
 * 20) Ropivacaine
 * 21) Tocainide
 * 22) Transcainide
 * 23) Xilobam
 * 24) Xipamide
 * 25) Xylazine

Many of these are local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.

-- Jytdog (talk) 02:32, 21 September 2017 (UTC)