Talk:5-HT7 receptor

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"The 5-HT7 receptor plays a role in smooth muscle relaxation within the vasculature and in the gastrointestinal tract.[1]... The 5-HT7 receptor is involved in thermoregulation, circadian rhythm, learning and memory, and sleep. "

How is the effect of this receptor when agonized or antagonized. Smooth muscle is relaxed when receptor is agonized or antagonized? Anybody knows it? And the same i wanna know when it comes about termoregulation, memory etc.

Im takins amisulpride 50-100mg. This drug antagonize 5ht7a. I have no problem sleeping, learning and good memory. So probalby antagonizm of 5ht7a improve these things.

I also have problems with cold hands (shrinked vessels) especiali in the mornings and gastrointestinal tract. It could be becouse of i am nervous, anxiety, depresed etc but im knot sure of amisulpride's involvment at this. Recently i also have a little bit elevated body temperature for long time (sometime is normal somethimes not). And im knot sure if it is some kind of infections or maybe amisulpiride and it's 5ht7a antagonism... — Preceding unsigned comment added by 109.241.248.66 (talk) 14:40, 22 October 2014 (UTC)
 * Welcome to Wikipedia! Please note that we cannot offer medical advice here. Your first questions (regarding activation / antagonism of the receptor) could probably be asked at, but also there specific medical advice is off-topic. Please discuss your specific case and side effects with a doctor. MichaK (talk) 17:47, 22 October 2014 (UTC)

Assessment comment
Substituted at 06:09, 29 April 2016 (UTC)

Why don't I see anything about the affinity this receptor has for psychedelic compounds?
Following the work of Thomas Ray I am intrigued by the effects the 5-HT7 receptor is supposed to have: https://transformpress.com/images/Downloads/S02Methods.pdf. I am wondering why I don't see anything about this research on this page. Is it because these effects are still deemed to speculative? — Preceding unsigned comment added by 77.251.116.230 (talk) 11:46, 11 January 2022 (UTC)