Talk:7-Hydroxymitragynine

IUPAC confusion.
I've come across two systemic names, but am uncertain to which is the IUPAC proper. I was bold and added one of the two, the other, shorter, one is: (7α,16E,20β)- 1,2,16,17-Tetradehydro-2,7-dihydro-7-hydroxy-9,17-dimethoxycorynan-16-carboxylic acid Methyl Ester Nagelfar (talk) 15:29, 25 November 2011 (UTC)

Clarification of Gastrointestinal Smooth Muscle Contraction Inhibition
I just added that on of the study's main points was that oral 7-hydroxymitragyne had much less of a constipating effect than a comparable dose of oral morphine. Vajko (talk) 09:08, 18 February 2012 (UTC)

note
this was added to the article in these diffs, but it is Talk page stuff, discussing what we should or should not have in the article, so i moved it here, and signed it for the editor who added it Jytdog (talk) 02:33, 31 August 2017 (UTC)

Some recent research on 7-hydroxymitragynine discovered that compared to morphine who is a full agonist. It has an intrinsic activity between 99%-104% so we can say that 7-Hydroxymitragynine is a full agonist not a partial agonist like it was said before. The potency compared to morphine need to be revised too it's closer to 13 time the potency of morphine but with a far better oral bioavailability

-- — Preceding unsigned comment added by 92.137.50.232 (talk • contribs) 02:20, 31 August 2017  (UTC)

More abuse potential than mitragynine, potentially more lethal, and being used as an adulterant in kratom
This article makes 7-OH-M sounds quite nice. I think the recent research has shown that actually 7-OH-M is a large contributor to the abuse potential of kratom and possibly also the potential lethality when kratom is adulterated with more 7-OH-M to make it more potent. I would just fix the article myself, but, whenever I try that, it seems some editor takes offense, so if there is anyone brave enough, please fix the article. Here's a reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135684/

--Joelrosenblum (talk) 07:20, 2 August 2019 (UTC)
 * That article does not support your statement. What it says ios "We found multiple commercial Kratom products to have concentrations of 7-hydroxymitragynine that are substantially higher than those found in raw M. speciosa leaves." It makes no conclusory statement about the contribution to kratom abuse, and kratom itself is addictive so that is not an easy thing to assess. Guy (Help!) 07:52, 2 August 2019 (UTC)