Talk:Adrenal gland/Archive 1

Testosterone
I thought hi mom made on the Testicles...
 * uhhhhhhhh yea testicles to a lesser extent) by the adrenals. --David Iberri (talk) 23:21, 8 March 2007 (UTC)

Sex Hormones or Steroids?
are wehn yewr h0rny/ Are testosterone and estrogen considered steroids or hormones? My teacher says they are produced in the cortex, but it says here that only the catecholamines are produced in the cortex. My teacher said testosterone and estrogen are produced in the medulla. Which is right? Dan 07:54, 28 March 2007 (UTC)
 * Testosterone, estrogen, etc. are all considered steroid hormones. Adrenal steroids are synthesized in the cortex while catecholamines are synthesized in the medulla. The article currently reflects these facts; where are you reading that "only the catecholamines are produced in the cortex"? That most certainly is incorrect. Cheers, David Iberri (talk) 22:58, 7 April 2007 (UTC)

Adrenal gland removal
Some emergencies require you to have your adrenal glands removed. How does that affect you? do the synthetic chemicals work as well, and what about the fight-or-flight response, is that basically gone?


 * Adrenals are not typically the subject of emergency removal. The spleen is the usual suspect. Unilateral adrenalectomy (on one side) leads to a brief decrease in cortisol levels which may require some suppletion therapy. The fight-flight response does not disappear on bilateral adrenalectomy (there is still an autonomic nervous system left to serve this function), but it makes the patient dependant on hydrocortisone and fludrocortisone suppletion. JFW | T@lk  18:12, 20 December 2005 (UTC)


 * Bilateral adrenalectomy is fatal unless the hormones are replaced artificially. This is primarily because the adrenal produces mineralocorticoids like aldosterone required for sodium, potassium and water homeostasis. The loss of cortisol production is also fatal over a longer period. In research adrenal glands are often removed from rodents when studying stress responses. In order to survive the animals must be given saline to drink. —The preceding unsigned comment was added by Povmcdov (talk • contribs) 12:57, 26 February 2007 (UTC).

Desert185 14:57, 30 July 2007 (UTC)== Products of the Adrenal ==

I would be interested to see a journal reference for the statement that the zona fasciculata "have the same functions as cells of the zona fasciculata". The textbook view (for example, Junqueira and Carneiro, Basic Histology 11th ed) is that the z. fasciculata produces cortisol and the z. reticularis produces androgens.


 * Thats what my source says too (lecture notes). Also the zona glomerulosa produces mineralocorticoids. Povmcdov 12:59, 26 February 2007 (UTC)

My four month old grand daughter has been diagnosed with cancer on one of the adrenal glands. She is scheduled to have it removed today. What long term impact will there be if they remove one of the adrenal glands?

Cortical layers
I edited out the references to the zona glomerulosa and zona fasciculata because the context they were originally used in may have confused readers into thinking that the z. glomerulosa and z. fasciculata were the adrenal medulla and cortex (respectively). More importantly, the z. glomerulosa and z. fasciculata are really the top two of the three layers of the adrenal cortex (the third, and deepest, is the z. reticularis). Also, the adrenal glands are not part of the sympathetic nervous system proper. It is more accurate to say that they are innervated by, and respond to stimulus from, the sympathetic nervous system. In another maniacal editorial rampage, I edited out "endocrine gland" because all glands are part of the endocrine system.


 * Sorry to interrupt, but all glands are not part of the endocrine system; some, such as sweat glands, are exocrine. --Diberri 01:52, Apr 7, 2004 (UTC)

As if now (Mon Mar 18 02:38:51 PST 2002), there needs to be some more deliniation and writing up of the anatomy of the different stuf, the role of angiotensin II, etc.). - user:redmist

i don't understand why there are no reference to the cortical layers in the main article..every histology or physiology book focos it, and is functionaly very importante...diferent layers, diferent hormones, and the influence in each other production because of the interrelation with circulation.. —Preceding unsigned comment added by 85.139.112.80 (talk) 15:28, 22 September 2007 (UTC)

Kidneys incorrectly shown on the picture.
On the anatomy picture, kidneys are marked incorrectly as 'pancreas'. —Preceding unsigned comment added by 87.252.227.43 (talk) 20:27, 19 May 2008 (UTC)

I was wondering
What happens if I eat one? Someone said I'd trip balls if I did cause of the overload of adrenaline and that's why cannibals thought they were absorbing the power of their half eaten foes when they ate them.. — Preceding unsigned comment added by 58.106.91.47 (talk) 14:30, 27 June 2012 (UTC)

Structure
In structure you stated that it weighs 256-295 pounds, did you mean 2.56 to 2.95 pounds? I mean I don't have any scientific proof to prove you are wrong. If you meant to state that, I can't figure out how I weight 140 pounds?... If my body weights 140 pounds how does something in my body weigh 256-295 pounds... and I still weigh 140.... It made me want to stop reading and I didn't know if I could trust the rest of the document, which seemed very informative until that point. So I thought I would tell you about it, to not deter others. ;) --Nashataku (talk) 04:48, 30 March 2014 (UTC)

No embryology?
66.64.72.10 (talk) 13:27, 7 August 2014 (UTC)
 * In progress ;). The prenatal development of adrenal glands is quite an interesting subject and there are lots of good sources available. --Tilifa Ocaufa (talk) 07:16, 12 January 2015 (UTC)
 * ✅. I hope the section is OK and makes a good start point for further development ;). --Tilifa Ocaufa (talk) 13:34, 13 January 2015 (UTC)

Merge
I merged the adrenal cortex and adrenal gland articles per the request of USER:Kosebamse who wrote on my user page that having too many pages makes it hard to know what is in the encyclopedia. I don't agree, but i don't really care how it is, and I think I'll do it Kosebamse's way. I'll see if there are other articles I developed in too much detail and that could be merged with a master article. SoCal

Comparative anatomy
Some comparative anatomy and physiology would definitely fill a huge void in this largely anthropocentric article. --Diberri | Talk 01:21, Apr 13, 2004 (UTC)

Anatomy pic
Someone please add a picture of location in the body!! thx
 * I added an image from Gray's Anatomy, but it doesn't highlight the adrenals particularly well. Hopefully someone can find a better pic. --David Iberri | Talk 22:03, Jun 23, 2005 (UTC)

I was wondering
What happens if I eat one? Someone said I'd trip balls if I did cause of the overload of adrenaline and that's why cannibals thought they were absorbing the power of their half eaten foes when they ate them..

In other animals
For future editors, there is a whole book relevant: "https://books.google.com.au/books?id=iHrAAgAAQBAJ&dq=adrenal+gland+location+variation&lr=&source=gbs_navlinks_s" --Tom (LT) (talk) 08:16, 1 August 2015 (UTC)

Planned rewriting of the article
I'm planning to do a complete revision of this article. While I think it's considerably well written, it needs some cleanup and there are text that belongs under different sections. Also most of the Function section is about not the production of hormones by the gland but the effects of such hormones in the body. What I plan to do here: I'm not deleting any text here, as I said it is quite well written. If someone is willing to give a hand or some advice it will be much appreciated ;). --Tilifa Ocaufa (talk) 11:43, 22 January 2015 (UTC)
 * Rewrite the lead section ✅
 * Expand Structure ✅
 * Add text about hormone synthesis by the gland in Function ✅
 * Reorder text to the correct sections ✅
 * Revise Clinical significance ✅
 * Cleanup and copyedit
 * Add images as needed ✅
 * Update: I pretty much finished adding text to the Function section. I think it covers most of the necessary information now, and I don't want to keep going as that would make it unnecessarily long and complicated. It may need some tweaks and additional details though, and most certainly lots of revision. I have a draft for the lead ready and I'm thinking whether or not to expand Clinical significance (which I think I'll just tweak a little, but other editor's opinions are appreciated). --Tilifa Ocaufa (talk) 07:59, 6 February 2015 (UTC)
 * 2nd update: I ended expanding most of the items in Clinical significance. I think this gives a more complete context and doesn't leave readers wanting for more that much. I've just uploaded the lead too. Its length somewhat concerned me, but according to WP:LEADLENGTH it's ok to have four paragraphs if the article is longer than 30K characters. I promise not to add more heavy amounts of text, but I plan to find sources for some statements and make some minor edits the following days. --Tilifa Ocaufa (talk) 08:46, 11 February 2015 (UTC)
 * @ did not see this at the time... the article looks fantastic. --Tom (LT) (talk) 07:52, 26 July 2015 (UTC)
 * I only see a few unreferenced sections, but that could be fixed quickly and then we can send it for WP:GAN! -- CFCF  🍌 (email) 21:49, 31 July 2015 (UTC)
 * makes a good point. I also prefer 16 to 15 because it has more factors and is a power of two (1, 2, 4, 8, ...). If that's the case, I better start adding some citations. --Tom (LT) (talk) 07:20, 1 August 2015 (UTC)
 * @ I may have accidentally reinserted an image you removed. Sorry about that, please go ahead. --Tom (LT) (talk) 07:52, 1 August 2015 (UTC)
 * @, @ only a few sections need references. Am happy to nominate when you two are. --Tom (LT) (talk) 08:17, 1 August 2015 (UTC)
 * No problem, the image just seems to have been duplicated. Anyway, I'm a little unsure with these very wide and short images. They're very hard to use, and I'm thinking of centering it. What do you think? -- CFCF  🍌 (email) 08:42, 1 August 2015 (UTC)
 * In my opinion, No harm in experimenting, although there may be a number of silent editors lurking in the background who vehemently object to this.--Tom (LT) (talk) 11:17, 1 August 2015 (UTC)
 * @, @: Just pinging to tell you I'm alive :P. Thanks for taking the time to expand the article! I think the image tells a lot about the organ but it looks weird in my display (the text is all cluttered in the right). Currently we have two Development sections, one under 'Structure' and the other under a header of its own. Would you consider merging these? --Tilifa Ocaufa (talk) 23:27, 3 August 2015 (UTC)
 * Good to hear from you! Whoops -- that's a very diplomatic way of pointing that out, I must have selective blindness. Very happy if those sections are merged. --Tom (LT) (talk) 11:12, 4 August 2015 (UTC)