Talk:Angiotensin-converting enzyme

Untitled
Removed unrelated spam Aasitsummer (talk) 08:00, 19 May 2008 (UTC)

Suggests to add
Ranges, including pediatric

Out-of-range: differntial diag.

Aasitsummer (talk) 08:05, 19 May 2008 (UTC)

I am the Director of Experimental Pathology at Cedars-Sinai Medical > Center. I am also a world expert on the enzyme angiotensin converting enzyme (ACE). I just wrote a 46 printed page review of ACE for Pharmacological Reviews that has about 520 references on ACE. Here is the reference:

A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme. Bernstein KE, Ong FS, Blackwell WL, Shah KH, Giani JF, Gonzalez-Villalobos RA, Shen XZ, Fuchs S, Touyz RM. Pharmacol Rev. 2012 Dec 20;65(1):1-46. doi: 10.1124/pr.112.006809. Print 2013 Jan. Erratum in: Pharmacol Rev. 2013;65(1):544.

I was hoping there was some way to link this article to this page to make the ACE page much stronger. I cannot do this by myself but I need an independent editor to do it.

Thank you,

Ken BernsteinKenbernstein (talk) 00:31, 21 May 2013 (UTC)

There are two forms of the enzyme in humans, the ubiquitous somatic ACE and the sperm-specific germinal ACE https://www.ncbi.nlm.nih.gov/pmc/articles/PMC193637/ — Preceding unsigned comment added by Ephrone (talk • contribs) 19:47, 21 March 2020 (UTC)

English please
I appreciate having the real experts apparently maintaining these pages on medications. However, we lay people -- the type who would be looking for information on Wikipedia instead of in a medical library -- don't speak or understand medical jargon or functions. Beyond that, what happens in a person's body after this drug converts whatever into whatever? From what I can infer, this explanation only talks about the first step in the process initiated by this drug. Give us real-world information, please! Otherwise this article is useless. --Boradis (talk) 03:43, 11 November 2008 (UTC)

Please consider the above echoed!! —Preceding unsigned comment added by 24.27.239.110 (talk) 07:25, 14 March 2010 (UTC)

I am not sure what you mean by real world information but if you want an overview of the process that ACE is involved in, have a look at the renin-angiotensin system page (linked in the first paragraph). Sadly it is still full of medical jargon but that is necessary for a full explanation. Murdochious (talk) 01:19, 23 March 2010 (UTC)

Disagree with orginal comment. There should be no reason ro reduce this to Layman terms. it is written perfectly for students that are studying this material. — Preceding unsigned comment added by 97.114.106.116 (talk) 06:19, 30 July 2015 (UTC)

More needed
Not a word about the diagnostic use of ACE in granulomatous conditions, and no indication what its concentration in human serum might be. JFW | T@lk  21:33, 11 April 2010 (UTC)

"Genetics & C and N Domains With Important Functional Difference" Section
After a few sentences, this section reads just...wrong. It appears to become incoherent, incomplete sentences that don't actually indicate anything clear about ACE - almost like someone uploaded notes on the enzyme onto here. Just look at all the semicolons! Anyway, I'm not even sure what the original author is trying to express, and genetics isn't my strong suit, so if someone could try and clean this up, that'd help me out, for one, and make the article as a whole more clear. 67.132.105.128 (talk) 17:44, 23 July 2010 (UTC)

athlete populations
Isn't there some recent studies into whether Everest summiteers, or olympians, or some such, carry this gene with a different frequency to the rest of the population? Cesiumfrog (talk) 09:16, 9 June 2012 (UTC)