Talk:Atrial natriuretic peptide

Untitled
This article is severely flawed. ANP is secreted in response to high BP and high BV. Not low. —Preceding unsigned comment added by 124.185.182.104 (talk) 12:52, 6 February 2010 (UTC)

Content has since been updated by expert on subject, formatting improved by Wikipedia community. This is no longer a starter. Could be improved with additional citations for many of the list items. Gtsulab (talk) 16:27, 14 September 2015 (UTC)

Other natriuretic factors
We've get 3 statements about animal NP in this section - two are referenced with primary research, one is unreferenced. Delete? IiKkEe (talk) 16:39, 9 September 2017 (UTC)

My recent edits
My recent edits of this Page - the Lead, and the Physiologic effects section - declare that all effects of ANP are caused by volume changes mediated by the kidney: this is clearly incorrect. Bear with me: I will re-edit these two parts reflecting current knowledge as soon as I finish digesting a 40 page online chapter on the subject from Seldin's textbook The kidney (2013). IiKkEe (talk) 00:07, 10 September 2017 (UTC)

Copyright violation
Lesson learned: I thought paraphrasing with attribution of source was OK. IiKkEe (talk) 12:26, 11 September 2017 (UTC)

Queen's University Student Editing Initiative
Hello, we are a group of medical students editing this page as part of our class assignment. We have compiled a list of suggestions to improve this article and would appreciate community feedback before we proceed with these edits. Here is a list of our suggestions:

1. We propose to change the Introduction section to include a general definition of natriuretic peptide as a class and then describe ANP's specific function.
 * Thanks for the this suggestion. Please indicate the exact wording of the changes. Also consult WP:MEDMOS as the lead of the article is written in a different style from the body.https://en.wikipedia.org/wiki/Wikipedia:Manual_of_Style/Medicine-related_articles#Lead JenOttawa (talk) 01:25, 6 November 2018 (UTC)
 * There is no "introduction" section. The section above the table of contents is the lead and all that it does, is summarize the body of the article (the part below the table of contents). See WP:LEAD.  Jytdog (talk) 02:31, 6 November 2018 (UTC)

2. We also propose to delete the sentence in the Introduction describing nine natriuretic peptides because there was no reference for it, and it was inconsistent with literature we researched reference as well as with the general Wikipedia article for natriuretic peptides.

3. We propose to add more specifics to the cardiovascular effects section as well as provide a reference because that section currently doesn't have one. More info can be found in the sandbox User:JerQueens/sandbox
 * I looked at this sandbox. References choices look good as per WP:MEDRS. Be sure to insert your references the same way each time (immediately after the punctuation like this.1JenOttawa (talk) 01:25, 6 November 2018 (UTC)

4. We plan on adding more information to the biomarkers section because a clinically important biomarker is left out and provide context to how they are used. Full edit can be found here User:JerQueens/sandbox —Preceding undated comment added 19:18, 5 November 2018 (UTC)

5. We plan on modifying the Production section of the article aim in order to properly illustrate the specific gene length of NPPA, its location within atrial myocytes, and how cleavage of the polypeptide yields the active form of ANP. The original article lacks citations for most of the information within the ‘Production’ section and does not provide enough detail to a non-medical reader. Please visit the following sandbox: https://en.wikipedia.org/wiki/User:NeednAdvil/sandbox
 * I know that it is hard to write technical information like this in lay terms. Try to add as many Wikilinks as you can, quite a few more terms can be linked.JenOttawa (talk) 01:32, 6 November 2018 (UTC)

6. To solidify knowledge as to its location of storage, we also plan on adding in a figure generated by Dr. Stephen Pang at Queen's University, elucidating the area within the atria that ANP is stored. — Preceding unsigned comment added by NeednAdvil (talk • contribs) 19:23, 5 November 2018 (UTC)
 * Please have Dr. Pang add the image to commons and make sure that the image can be used freely. You can add a link to the image to the talk page as well. If you need help, please let me know.JenOttawa (talk) 01:36, 6 November 2018 (UTC)

7. We also propose to add another section under the physiological section of the page called Immune system because currently there is no information on the page linking ANP to immune system.
 * Please provide a link to exactly what you want to add or write it in here so we can take a look. Thanks!JenOttawa (talk) 01:41, 6 November 2018 (UTC)

8. We propose to add information about ANP’s effect on innate, adaptive immunity as well as its cytoprotective effects under the Immune System section. https://en.wikipedia.org/wiki/User:Toastie145/sandbox
 * Thanks for sharing this work. I made a few small copy edits in your sandbox. It is not clear how this information will be organized. Is this one paragraph or separate points? Be sure to insert your references the same way each time, immediately after the punctuation like this.1 Great work so far!JenOttawa (talk) 01:41, 6 November 2018 (UTC)

Reply: Thank you for your comments! The information will go under the physiological section of ANP with the title Immune System and will be organized using bullet points like the rest of the section. — Preceding unsigned comment added by Toastie145 (talk • contribs) 17:13, 13 November 2018 (UTC)

9. We also propose to add more details in the renal physiology section specifically related to sodium reabsorption and glomerular filtration. User:Queen'smed22 —Preceding undated comment added 19:29, 5 November 2018 (UTC) https://en.wikipedia.org/wiki/User:Queen%27smed22/sandbox — Preceding unsigned comment added by Queen'smed22 (talk • contribs) 19:32, 5 November 2018 (UTC)
 * Thanks for sharing your suggestions. I have a few notes to help"
 * I think you can add quite a few links to the technical terms (note we only need to add wiki links the first time the term is used in the WP article.
 * Be sure to insert your references the same way each time, immediately after the punctuation like this.1
 * I think you can try to add in a little more lay termnology. One example could be to replace the word "unanimous".
 * Your group is doing a great job!JenOttawa (talk) 01:50, 6 November 2018 (UTC)

10. We also propose to add more details regarding the effectiveness of ANP for the treatment of heart failure. While this molecule is used as a medication in some parts of the world, some research shows that ANP may not be a viable treatment for this condition. Please view this link for our proposed change: https://en.wikipedia.org/wiki/User:Queensmedicine2022/sandbox Christiemclaren (talk) 19:11, 5 November 2018 (UTC)
 * I think you did a great job finding secondary sources here. It is not easy in this type of article a common error. Be sure to insert your references the same way each time, immediately after the punctuation like this.1 Can you try to find a few terms to link? JenOttawa (talk) 01:50, 6 November 2018 (UTC)

Reply: Thank you for your review. I will review the citation style and make sure that t is uniform. I will also link several other terms to other wikipedia articles for easier read. — Preceding unsigned comment added by Queensmedicine2022 (talk • contribs) 17:02, 13 November 2018 (UTC)


 * This page should follow the sectioning and style described at WP:MCBMOS. The sourcing should all be per WP:MEDRS. Jytdog (talk) 02:31, 6 November 2018 (UTC)

Link to sleep apnea / apnoea
Neurologist Guy Leshziner describes in "The Nocturnal Brain" Page 83 (hardback) that ANP is produced in spikes many times a night in relation to sleep apnea / apnoea. This is an important but incredibly poorly understood symptom of sleep apnea/apnoea, and a major issue: sleep is disturbed by apnea/apnoea which causes ANP spikes which disturb sleep which causes worse symptoms: I am medically trained and had no idea the heart secreted hormones to control blood volume thinking it was done through kidneys: Drs should be aware patients presenting with "I snore and have to get up in the night to pee so much it disturbs my sleep" likely have *severe* sleep apnea/apnoea and are at high risk. Can someone please add this ? Thanks 92.1.65.238 (talk) 08:07, 7 April 2023 (UTC)