Talk:Autophagy protein 5

Wiki Education Foundation-supported course assignment
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Jwan225.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 13:12, 16 January 2022 (UTC)

Atg5 is E3 ligase?
Atg5 is the substrate of Atg12 and can form complex with Atg16. However, the E3 ligase of Atg5 is not defined as far as I know. Could anybody give citation of "Atg5 is ubiquitin E3 ligase"? — Preceding unsigned comment added by 137.222.52.183 (talk) 16:04, 24 November 2013 (UTC)

Here E3-like activitiy of Atg12-5 for Atg8 is described first: Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y. 2007. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem. 282(52). PMID: 23064152 --134.95.232.136 (talk) 12:33, 22 March 2019 (UTC)