Talk:Beclometasone

Beclometasone
I don't see why this page was changed from the original redirect to beclometasone dipropionate. Terrace4 06:16, 25 April 2006 (UTC) I agree. Why is this page still here? It should be merged into the beclometasone dipropionate page. Possibly put in a disambiguation page to redirect beclomethasone to beclometasone. Daunorubicin 14:45, 1 August 2006 (UTC)


 * Here is why. -- Boris 10:03, 29 May 2007 (UTC)

In response to a message from User:BorisTM, I thought I should explain why I changed this article title to beclometasone (as opposed to beclometasone dipropionate, beclomethasone or beclomethasone dipropionate). Beclometasone is the International Nonproprietary Name specified by the World Health Organization and should be the title according to Naming conventions (chemistry). Beclometasone dipropionate is the INN Modified (INNM), albeit on that more accurately describes the actual molecule administered. Most clincians refer to the beclometasone dipropionate as simply "beclometasone". To avoid ambiguity, I've changed the article title back to the INNM. -Techelf 10:46, 16 June 2006 (UTC)


 * Hi, Boris.


 * 1) Are you aware that the spelling of "beclomethasone" has been changed to "beclometasone"?
 * 2) Are you aware that the drug in all of those proprietary preparations (Beclovent, Vanceril, Qvar, Beconase, etc.) is actually "beclometasone dipropionate"? Axl 08:19, 30 May 2007 (UTC)


 * If the name has been changed to beclometasone i don't see why beclometHasone shouldn't redirect to beclometasone. I don't know what is the actual composition of those preparations neither i am the one who has added that information, but if that's the case then it should be romeved from the beclometasone page and any other information that is actually relevant to the chemical compound beclometasone dipropionate. I suggest that a new page "Beclometasone (disambuguation)" is created that explains all that and has links to both Beclometasone as the real chemical and Beclometasone (which is BDP) as the drug. I would leave that to you to decide how to do it but i have to insist that we keep the page for the chemical "Beclometasone". -- Boris 13:23, 30 May 2007 (UTC)


 * Okay, thanks. Axl 21:27, 30 May 2007 (UTC)

Beclometasone per se is not used at all in UK, either topically for eczema nor inhalled for asthma. When used in clinical setting it is always in the UK as an abbreviation for Beclometasone Dipropionate (nasal spray of Beconase, topically as Propaderm, Becotide/QVAR/etc inhalers for asthma). Indeed "Beclometasone" inhaler is an accepted generic term but is supplied as Beclometasone Dipropionate. So unless US availability is different, then "Beclometasone" is an accepted alternative name for BDP and should therefore be a redirect. David Ruben Talk 23:31, 30 May 2007 (UTC)

Look at Betamethasone where again single word used, but a variety of salts listed all of which in themselves do not make a lot of difference in considering "Betamethsone" as a clinically used steroid.David Ruben Talk 23:34, 30 May 2007 (UTC)
 * Noticed Boris's post on WT:PHARM. I was going to ask whether beclometasone proper was ever used, but apparently David summed it up nicely above :) Fvasconcellos (t·c) 02:39, 31 May 2007 (UTC)


 * I've been bold and re-redirected Beclometasone to Beclometasone dipropionate, for above reasons but with a rephrasing and a qualification. As Beclometasone is only ever clinically used as Beclometasone dipropionate, "Beclometasone" is thus not notable in itself (ie does not need separate article) but should (as in its clinical use) redirect to BDP. The main reason is thus to have a single article about a single clinical entity and is similar to the single article of Betamethasone. The difference though is that Betamethasone is used as a number of different salts, so the article chosen is Betamethasone (rather than any specific salt), whereas "Beclometasone" only ever clinically implies Beclomethasone dipropionate, hence the choice as to which is the article and which should be the redirect.
 * Now for the qualification: if Beclometasone were ever to start to be significantly used as a salt other than the diproprionate, then like Betamethasone, I would agree that all the details should be under a single article again of Beclometasone ... David Ruben Talk 11:50, 31 May 2007 (UTC)
 * Sounds quite reasonable. By the way, BDP is still the INNm, so the article technically still meets WP:PHARM naming conventions, right? Just a curiosity, but I wonder if anyone would agree with me... Fvasconcellos (t·c) 02:18, 1 June 2007 (UTC)

Addictive
Can anyone find a citation about the "highly addictive properties"? I don't think steroid inhalers are generally considered addictive and a quick googling turned up nothing of the sort. Squidlarkin (talk) 07:38, 28 August 2008 (UTC)
 * Inhaled corticosteroids are not considered addictive. I've removed it from the article. Fvasconcellos (t·c) 17:35, 29 August 2008 (UTC)


 * The article does indicate a rebound issue on skin treatment, which tends to result in addictive continuing use. The article may cover this adequately as is.

66.167.61.217 (talk) 20:36, 23 May 2010 (UTC)

Other Usage
Recently, I found that Beclomethasone Dipropionate is used in an Anti-Haemorrhoidal Cream too. In India a cream with the brand name Anovate is used for treating Haemorrhoid. The cream contains Phenylephrine Hydrochloride and Lignocaine Hydrochloride. Chlorocresol is used as a perservative in this cream. Dr. Dinesh Karia (Talk) (contribs) 12:12, 20 October 2009 (UTC)

Qvar, etc. need their own pages to tell, e.g., what are the "inactive" ingredients in each.
Qvar, and other mass-marketed formulations containing Beclometasone each need their own pages to tell, e.g., what are the "inactive" ingredients in each. E.g., many formulations still contain benzalkonium chloride notwithstanding substantial evidence that it interferes with function of the cilia of the mucociliary escalator for the respiratory epithelium.

As far as I've been able to find on the web, the inactive ingredients of Qvar are Norflurane and ethanol.

The package insert states:


 * "QVAR is a pressurized, metered-dose aerosol intended for oral inhalation only. Each unit contains a solution of beclomethasone dipropionate in propellant HFA-134a (1,1,1,2 tetrafluoroethane) and ethanol."

http://www.qvar.com/Document/PrescribingInformation.pdf

66.167.61.217 (talk) 20:34, 23 May 2010 (UTC)
 * That sounds like a disaster. Can be discussed here. Doc James  (talk · contribs · email) 09:08, 17 March 2019 (UTC)

Merged with
The prodrug beclometasone, which was here. Makes no sense having the two especially since the ester is by far the more common and beclometasone is the common name for it. Doc James (talk · contribs · email) 09:07, 17 March 2019 (UTC)

Need clarification and elaboration
"Beclomethasone dipropionate was first patented in 1962 and used medically in 1972. It was approved for medical use in the United States in 1976." Where had this material been patented (in 1962), where was this drug approved for medical use （in 1972）, and where can we get the info about it was approved in 1976 for medical use in the States (I'm unable to get it through related citation). As for "Beclometasone dipropionate is the INN modified and beclomethasone dipropionate is the USAN and former BAN. It is a prodrug of the free form, beclometasone (INN)." Can anybody use plain language to express, making a layman like me to better understand? Thank in advance for your knid attention. ThomasYehYeh (talk) 07:59, 18 February 2024 (UTC)