Talk:Biperiden

Availability
This drug is discontinued manufactured in the U.S. I take it. I need it! Please find out if someone knows about if it will ever be made again. Thank you — Preceding unsigned comment added by 75.161.136.190 (talk)

receptors binding
Potent, selective M1 receptor antagonist (Ki values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M1, M4, M3, M2 and M5 receptors respectively). http://www.abcam.com/Biperiden-hydrochloride-ab141781.pdf https://www.scbt.com/scbt/product/biperiden-hydrochloride-1235-82-1 — Preceding unsigned comment added by 109.241.248.66 (talk) 15:30, 25 October 2014 (UTC)

Tourette syndrome treatment
Citation needed for biperiden's usage in treating Tourette syndrome.

All I could find was a case report of treating extrapyramidal symptoms caused by dopamine antagonists in a Tourette syndrome patient.

This one showed resolution of symptoms:

https://doi.org/10.1345/aph.1g331

I also found a case study of biperiden in a patient with schizophrenia and Tardive Tourette-like syndrome induced by antipsychotics, in which it appeared ineffective.

https://doi.org/10.1111/j.1440-1819.1992.tb00821.x

I could not find any source regarding the treatment of TS-proper with biperiden. Sappygang (talk) 12:33, 5 April 2024 (UTC)

Can anybody help clarify following
"Biperiden is no longer marketed in the United States." Is this statement correct? if so, the reason? Thank you for your kind attention. ThomasYehYeh (talk) 13:51, 5 May 2024 (UTC)