Talk:Briakinumab

Psoriasis
Here's a good story from HealthDay news that addresses some important unanswered questions in the NEJM article.

http://health.usnews.com/health-news/managing-your-healthcare/research/articles/2011/10/26/experimental-psoriasis-drug-bests-older-treatment

"Cancer risk is extremely hard to define, and this study was not powered to detect any difference in the risk of developing a malignancy," said Bebo.

He said that in an earlier trial of briakinumab, some unexplained major adverse cardiac events occurred. At the time, Abbott withdrew its application for approval from the U.S. Food and Drug Administration pending further research. In the current study, no serious cardiovascular events were reported.

Of the increased infections and cancers, Reich said, "Although these differences were not statistically significant, they lead to questions regarding a favorable risk-benefit profile of the drug." --Nbauman (talk) 05:02, 31 October 2011 (UTC)

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