Talk:Butylparaben

New information added by User:anthonna. I edited this page for part of a school project at Boston College. The assignment page is on wikipedia here: User:Hakeleh/BI513 Fall 2011. Please feel free to add to this page and make corrections. Anthonna (talk) 19:04, 24 October 2011

BI 513 Editing Comments
Anthonna, I thought this was a great article! Super informative and organized. These are a couple suggestions I have: 1) Maybe add some new research pertaining to the toxicity and carcinogenicity of butylparaben. Here are some articles I found on PubMed:   - http://www.ncbi.nlm.nih.gov/pubmed/25435060 - Associations between urinary phenol and paraben concentrations and markers of oxidative stress and inflammation among pregnant women in         Puerto Rico.    - http://www.ncbi.nlm.nih.gov/pubmed/25461396 - investigates link between butyl paraben concentrations and autism in rats     - http://www.ncbi.nlm.nih.gov/pubmed/24481588 - investigates link between butyl parabens and function of apoptotic gene expression as related to breast cancer

2) Maybe explain the Danish sewage study more because it was hard to understand the point of the study

Environdisruptersbad (talk) 21:24, 1 February 2015 (UTC)

Hi Anthonna, Great article! It was easy to understand, well organized, and very informative. It seems like you are on a really good track, but I thought of a few points you can add in to make it even better if you’d like. Bal

While reading the article myself, I found myself wondering…what about butylparaben do manufacturers find  to be so great that it continues to be a very commonly used substance  despite its possible negative health effects? It would be good for you to go a bit more into how exactly butylparaben acts as a preservative and how its antimicrobial effects are produced. Here are some articles I found that may help.


 * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC92888/


 * http://informahealthcare.com/doi/abs/10.1080/07853890701195262

To continue on this questioning, a little bit on why butylparaben continues to be used rather than natural alternatives would be interesting to read about? Are there even natural alternatives out there? What are the pros and cons of replacing butylparaben with these substances? Is there any reason in particular that they are preferred?


 * http://www.happi.com/articles/2005/05/preservative-update

As for some small additional adds:

- You said that butylparaben can decrease sperm production but did not go into that much detail about how androgen activity can be linked to elevated butylparaben levels, How do butylparabens decrease androgens?

- What are some of the future areas of research regarding butylparaben?

- It would also be good to see a new section on Influence on the World that looks at levels of bioaccumulation, concentrations found in humans, and how exposure to this substance can be avoided.


 * http://www.mendeley.com/research/fate-and-partitioning-of-selected-pharmaceuticals-in-aquatic-environment/


 * http://www.thegoodhuman.com/2007/06/21/what-are-parabens-and-why-should-you-avoid-them/

- Add links to lipophilic and estrogenic

Good luck, and I hope this helps! Hortonsb (talk) 06:43, 13 November 2011 (UTC)

I thought this was a great article. It was simple and easy to understand and it has good organization. Here are some of my suggestions: Hope this helps! Igoekr21 (talk) 14:25, 14 November 2011 (UTC)igoekr21
 * For the properties section, most of what is written here can be found in the chembox. You might want to add some more things that are not already in the chembox.
 * I also agree with hortonsb in that you can add more to reach neutral point of view. Why does butylparaben continue to be used? What is so good about it? What would happen to the cosmetics if they did not have butylparabens in them? You mentioned that they would decompose but I think you should add more to this. I think you should elaborate on the preservative and antimicrobial effects. If products don't have parabens, they have to be thrown away sooner.
 * Maybe you could add a section on regulations. Or change the history section to history of regulations? Talk about how parabens can end up in makeup- no regulations. The manufactures can put whatever they want in their products. http://www.fda.gov/cosmetics/productandingredientsafety/selectedcosmeticingredients/ucm128042.htm
 * I thought that all the toxicity sections were good and very clear. Maybe you could add a little explanation to the anti androgen section. Some people may not know what androgens are. Or just link to the anti androgen page.
 * What are the alternatives to parabens in cosmetics?

Thank you Hortonsb and Igoekr21 for your very helpful comments. I have tried to make all the recommendations you have given me here. For this draft of the wikipedia article I added information on why manufacturers use butylparaben, and how they are very useful to them. This should add to the NPOV perspective by highlighting what is good about butylparaben. I also added a section relating to alternative chemicals that can be used, as well as what can be done to avoid exposure. I did not want to elaborate too much on this however, because it may make the article lay too much on the negative side of the issue. I also added to the antiandrogen section that you both mentioned could use some work. I linked it to the antiandrogen page for further explanation as well. I also deleted some of the redundant information that I had in the properties section, which could easily be read in the chembox. Lastly, I added pictures from the wikimedia commons in order to provide some visuals. I look forward to more comments in the future and will check in periodically to see what can be done to make this article better. Thanks Anthonna (talk) 12:17, 12 December 2011

For the most part, this article is very well organized and easy to read through. I just have a few suggestions: Good luck! Hope this helps. Hwola (talk) 21:35, 31 January 2015 (UTC)
 * Under the Occurrence section, in the last part about the Danish sewage study, you could perhaps expand a little about what is meant by 'acute and chronic effect concentrations' and make it clear that this study was to assess the potential effects parabens could have on the aquatic environment and animals in each trophic level.
 * Under Ongoing and future research, you could rephrase the FDA's questions into sentences instead (it seems a little choppy if you list these questions all of a sudden without any further details or clarification)
 * Many of your links, including numbers 1, 3, 5, 11, 22, and 33, are no longer working. I did not list all of them but it would be great if you could check them.
 * Be sure to follow the strict rule WP:MEDRS i.e. zero references or discussion on biomedical topics unless backed by an authoritative review, and guidance WP:SECONDARY, i.e. Wikipedia prefers citations to reviews not primary journal articles.  --Smokefoot (talk) 21:53, 1 February 2015 (UTC)

Great Article! I liked how organized it was and straight forward. However, I felt some areas lacked a little detail.

- You noted that butylparaben can act as a natural estrogen in the body and bind to estrogen receptors. Could you provide more detail regarding when it binds to these what the results/dangers entail? -You also elaborated on how butylparaben can disrupt sperm function. I feel this section can have more detail and explanation as well. For example, I think it would be beneficial to explain the mechanism of how the exposure to butylparaben causes this disruption. - I was wondering if there are any other alternatives to butylparaben? Do food and cosmetic industries have an alternative that could be used? What are the pros/cons to the alternative? I am also very intrigued that Denmark banned the use of products containing butylparaben in children - I was wondering if there is any data displaying that this has been beneficial? For example, have cases of breast tumors or sperm disfunction's dropped?

Also, numerous links I clicked on did not work, so you may just want to go back and fix those! Besides that, I think this was very interesting to read about. I am especially interested in cancer and particularly breast cancer, because my mom was just diagnosed. Therefore, I really enjoyed reading this article and learning more about butylparaben. Good luck!! Kieradkeller27 (talk) 22:36, 2 February 2015 (UTC)kieradkeller27 - BI513 Spring 2015

Here is some new information as of January 2015 regarding Butylparaden: In the EU, no new products can be placed on the market that do not follow the new regulations after April 2015.

Kieradkeller27 (talk) 20:52, 7 March 2015 (UTC)kieradkeller27 - BI513 Spring 2015

Some Suggestions
Great job on the article! Very well written and the information is presented in clear manner. Here are just a few suggestions: Overall though fantastic job the article. Well done. Itoconnor7 (talk) 17:45, 1 February 2015 (UTC)Itoconnor7
 * In the Introduction, I would reword the first sentence to clarify that C4H9(C6H4(OH)COO is the formula for butylparaben and not all members of the paraben family. There is also a parentheses right after C4H9(C6H4(OH)COO that should be deleted.
 * In Uses and Reactions, I would remove the word “probably” after you write "Butylparaben is one of the most common bactericidal/fungicidal additives in cosmetics.”
 * In Regulation, I would expand on the minimum amount necessary to achieve its intended effect. What is this minimum? What is the intended effect

Really interesting and informative article! It was very concise and well organized. In terms of expanding on certain areas of the article, I think it would be interesting to know a little bit more detail about some of the studies. For example, why did Denmark regulate the use of butylparaben in children's products? What were the findings behind this? Also, it is mentioned that butylparaben is an endocrine disruptor. While the mechanism of action was discussed, it would have been nice to know a little more about the implications of this or the relation of this to the other sections in the article. Tiernestep (talk) 00:50, 3 February 2015 (UTC)

Anthonna, great article! I appreciate the concise and clear way you have crafted this page. Some suggestions: Thanks overall for a nice read! Helenma (talk) 14:45, 3 February 2015 (UTC)
 * Further discuss the American regulations (like at what concentrations and where, etc.)
 * Perhaps having a few examples of suspected butylparaben poisoning, links to news stories, etc., would add a little bit of flare
 * Further discuss what estrogenic products can do, or maybe link the world "estrogen" to its wikipage

Be careful

 * Before you act on the advice of your fellow undergraduates, please feel free to ask for advice from experienced editors.  If you are required to edit this article by your teacher, try to adhere to these guidelines: WP:SECONDARY and WP:MEDRS. Wikipedia does NOT seek news stories, it seeks citations to published reviews and textbooks.   --Smokefoot (talk) 13:22, 4 February 2015 (UTC)

External links modified
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I have just modified 10 one external links on Butylparaben. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
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 * Added archive https://web.archive.org/web/20111030154312/http://www.fda.gov/cosmetics/productandingredientsafety/selectedcosmeticingredients/ucm128042.htm to http://www.fda.gov/Cosmetics/ProductandIngredientSafety/SelectedCosmeticIngredients/ucm128042.htm
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