Talk:CHOP (chemotherapy)

What does the H in CHOP represent
this article separately describes the H in CHOP as being 'Hydroxyrubicin' and then 'hydroxydoxorubicin'. Which is it?

One one hand, this abstract: http://www3.interscience.wiley.com/cgi-bin/abstract/112706492/ABSTRACT?CRETRY=1&SRETRY=0

says, "Hydroxyrubicin is a synthetic analog of doxorubicin in which the basic amino group at the C-3 has been replaced by a hydroxyl group...". So they are not the same.

Yet this page: http://ctd.mdibl.org/detail.go;jsessionid=92F12340E7F4A23A86B9242140E2E2AE?type=chem&acc=C042907 says that hydroxyrubicin is indeed a synonym for doxorubicin. "Chemical Synonyms 3'-deamino-4'-epi-3'-hydroxydoxorubin; 3-DHD; hydroxyrubicin"

Kenmcl2 04:57, 3 July 2007 (UTC)


 * It must be doxorubicin. JFW | T@lk  06:07, 3 July 2007 (UTC)


 * According to PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=72398 hydroxydoxorubicin and hydroxyrubicin are same compound that is not doxorubicin but 3'-Deamino-3'-hydroxydoxorubicin where amino group has been replaced by a hydroxyl group. —Preceding unsigned comment added by Tanevala (talk • contribs) 17:18, 18 September 2007 (UTC)

H must come from Hydroxydaunorubicin which is a synonym for doxorubicin.

HIV
CHOP for DLBCL in HIV seems fairly safe JFW |  T@lk  09:59, 24 January 2008 (UTC)

Use of refs and notes
Original text uses {{ref - It might be better to change them to use <ref like most other articles ? Currently they allocate duplicate ref numbers. - Rod57 (talk) 18:32, 13 December 2012 (UTC)

When was it introduced
It would be great if article history section said when it was introduced and for what indications. - Rod57 (talk) 22:12, 15 December 2012 (UTC)

Is [R]-CHOEP similar to [R]-EPOCH?
Is [R]-CHOEP similar to [R]-EPOCH? If so there is already an article on [R]-EPOCH, which should be mentioned in this article. Else, I guess the difference should be explained. --Jacques de Selliers (talk) 17:17, 27 October 2017 (UTC)