Talk:Calitoxin/GA1

GA Review
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Reviewer: Sasata (talk · contribs) 02:27, 6 November 2014 (UTC)

Review coming soon. Sasata (talk) 02:27, 6 November 2014 (UTC)

Sorry for the delay ... here are some starter comments:


 * the lead is not yet a good summary of the article (see WP:LEAD for guidelines)
 * Symbol voting keep.svg how about now?  &mdash; Gaff  ταλκ 19:27, 19 November 2014 (UTC)


 * possibly useful wikilinks: neurotransmitter release, neuromuscular junction, stinging cell, amino acid sequence, homologous, voltage-gated sodium channel; Glu and Lys should be spelled out
 * ✅ &mdash; Gaff ταλκ 16:44, 18 November 2014 (UTC)


 * ”Calitoxin is a highly potent neurotoxin, which can be found in the nematocysts, organelles in stinging cells, of the Calliactis parasitica.” fix grammar
 * Symbol confirmed.svg better?? &mdash; Gaff ταλκ 16:54, 18 November 2014 (UTC)


 * ”Two genes coding for two highly homologous calitoxins are discovered and analyzed” fix
 * Symbol confirmed.svg &mdash; Gaff ταλκ 17:01, 18 November 2014 (UTC)


 * missing information: who discovered calitoxin, when, and under what circumstances? The short etymology section could perhaps be merged with this info
 * Symbol voting keep.svg renamed and expanded the section. Hopefully sufficient? &mdash; Gaff  ταλκ 21:16, 18 November 2014 (UTC)


 * has anyone quantified the amount of calitoxin in Calliactis parasitica?
 * Symbol possible vote.svg Not that I can find. I found the minimum dose (it is in the article).  The extraction method sounds pretty crude, so I doubt that anyone can say exactly how much is in there. &mdash; Gaff  ταλκ 04:00, 19 November 2014 (UTC)


 * ”by injecting a 0.1 mL solution with 0.2 µg lyophilized CLX of into the hemocoel.” this is far too much detail for a general encyclopedia
 * Symbol confirmed.svg &mdash; fixed. &mdash; Gaff ταλκ 04:00, 19 November 2014 (UTC)


 * what is the toxin's isoelectric point?
 * Symbol confirmed.svg done. &mdash; Gaff  ταλκ 17:22, 18 November 2014 (UTC)


 * are there any disulfide bonds?
 * Symbol confirmed.svg. There are three.  Added.  &mdash; Gaff  <b style="color:MediumSlateBlue;">ταλκ</b> 17:09, 18 November 2014 (UTC)


 * is the compound commonly used in studies of ion channels?
 * Symbol confirmed.svg&mdash; fixed. &mdash; Gaff <b style="color:MediumSlateBlue;">ταλκ</b> 04:00, 19 November 2014 (UTC)

Comments

 * The above concerns have been addressed. I've substantially expanded the article, added a table comparing the sequences, and restructured problematic sections.  Please let me know what else can be done to bring this to GA status.  &mdash; Gaff  <b style="color:MediumSlateBlue;">ταλκ</b> 19:27, 19 November 2014 (UTC)
 * The corrections and additions look great! I've made some additional copyedits and added more links; feel free to revert if you don't like them. I'm confident that this article now meets the GA criteria, and am happy to promote at his time. Cheers, Sasata (talk) 19:53, 21 November 2014 (UTC)