Talk:Cetylpyridinium chloride

Questionable information / inconsistencies
The article lists the molecular weight as 339.99 g/mol, but the second external link (chemicalland21.com) lists the molecular weight as 358.07 g/mol. What is the correct value? —Preceding unsigned comment added by 128.175.195.68 (talk) 17:48, 2 February 2010 (UTC)
 * This page has the molecular weight for cetylpyridinium chloride (C21H38NCl) and chemicalland21.com has the molecular weight for the hydrate (C21H38NCl·H2O). Both are correct in terms of what they refer to, but it's best for our article to stick with the parent compound as it is currently.  -- Ed (Edgar181) 17:56, 2 February 2010 (UTC)
 * Thanks for the clarification. —Preceding unsigned comment added by 128.175.195.54 (talk) 18:47, 4 February 2010 (UTC)

"...Oral Cavity Panel are sufficient to conclude that 0.025 to 0.1 percent cetylpyridinium chloride is safe as an OTC oral antiseptic when labeled for short-term use (not to exceed 7 days)." I'm looking at Crest Pro-Health Multi-protection alcohol free mouthwash which lists one active ingredient at 0.07% Cetylpyridinium chloride. The expectation is this is used every day. It is not labeled for 7 day treatment. — Preceding unsigned comment added by 2601:646:8E80:2A30:ECA8:D438:6960:1862 (talk) 19:32, 19 February 2017 (UTC)

Is this biased?
I don't know enough about the subject to claim that this is biased, and maybe it's just because it is very incomplete, but it makes the chemical sound so bad that it would make a better terrorist weapon then a mouthwash ingredient. It sounds like an attempt to get people to switch to listerine brand or something.

Can that really be true? A Google search quickly turns up studys that show that it does indeed reduce oral bacteria, contrary to what this article claims...

Someone smarter than me should look at this article.

Headybrew 22:47, 15 November 2007 (UTC)


 * I don't believe it is. Cetylpyridinium Cl has, to the best of my knowledge, always come with the caveat that it can cause temporary discoloring of the enamel. It might be effective as an oral health product, but it's not without its faults. Exigence (talk) 19:00, 20 March 2008 (UTC)


 * Nowhere on the Crest website, linked to by reference number 4, does it claim that brown stains are a possible side-effect of using the mouthwash. I checked the site thoroughly and have removed the invalid reference in the introduction.  The only thing I saw that was remotely close to this was the fact that the blue dyes in the "Clean Mint" flavour can stain some dental work and can cause temporary stains on teeth (which are removed with normal eating/drinking).Mkubica (talk) 03:23, 25 March 2008 (UTC)

Browned between my teeth
I have been using Crest Prohealth for a little over 2 years now. I brush using proper procedure at least twice a day. I have noticed in the past few months that the spaces between my teeth are stained brown. I recall reading about this a year ago but forgot until I read it again on this Wikipedia page. Definitely seems to match my experience.

Wtogami (talk) 07:15, 27 November 2007 (UTC)


 * It is very probable, that if you hadn't used the Cetylpyr-bromide mouthwash, your teeth would have gotten the same brown stain, because this is normal plaque discoloring that occurs to most people. Thats why you go to the dentist and have a full teeth cleaning every year. — Preceding unsigned comment added by 188.98.246.169 (talk) 23:46, 29 December 2014 (UTC)


 * Cetylpiridinium chloride, in many people, will absolutely cause unsightly brown staining. Crest Pro-Health faced a class-action lawsuit over this staining, and added a warning to the back of the bottle. My teeth were stained by it recently, and I was astonished to see that the first paragraph of this article claimed the opposite (until I removed the claim, which was unsupported by the given citation). See http://andywibbels.com/crest-pro-health-mouthwash-turning-customers-teeth-brown for hundreds of similar reports. — Preceding unsigned comment added by 146.115.134.154 (talk) 07:42, 20 February 2019 (UTC)

abbreviations
IPR-RAT LDLO 15 mg kg-1 IVN-RAT LD50 30 mg kg-1 ORL-MUS LD50 108 mg kg-1 ORL-RBT LD50 400 mg kg-1 IVN-RBT LD50 36 mg kg-1

where can I find the meaning of these ? I couldn't find it in wikipedia —Preceding unsigned comment added by Gsgs2 (talk • contribs) 12:59, 21 December 2007 (UTC)

This just happened to me too. I noticed this http://www.crestprohealth.com/pro-health-faq/#r7 on Crest's website which mentions the staining. The stains on my teeth are pretty severe but luckily they are mostly on the insides of my teeth so they are hard to see. They definitely happened since using a mouthwash containing Cetylpyridinium chloride. Also the taste thing is very real but is short term. It lasts for a few hours after using it. 98.140.0.68 (talk) 19:41, 22 March 2011 (UTC)

May it produce loss of equilibrium ?
Been using it as a mouthwash for some months.

I feel a loss of stability with fear of falling on the floor. —Preceding unsigned comment added by 79.177.0.58 (talk) 18:55, 27 July 2008 (UTC)

Potentially unsourced harmful LD50 data removed
IPR-RAT LDLO 15 mg kg-1

ORL-MUS LD50 108 mg kg-1

-Temporal User (Talk) 14:18, 7 February 2011 (UTC)

What products contain this?
The most important info that's missing from this article is a list of popular products that contain this substance. Gronky (talk) 14:10, 11 May 2011 (UTC)

At least this: http://www.dentylactive.com/faqs Two key ingredients in Dentyl Active are Cetylpyridinium Chloride (CPC), an antibacterial agent, and Sodium Fluoride which helps to support healthy teeth and gums.

ee1518 (talk) 10:34, 20 August 2015 (UTC)

Synonyms
I'm not sure but I doubt that there are commercial products with the following names: 1-palmitylpyridinium chloride, C16-alkylpyridinium chloride or 1-hexadecylpyridinium chloride. I'm guessing that someone put those names here because they are in fact "synonyms", but the sentence needs to be rewritten squeeze them in properly. Hopefully someone better qualified than myself will pitch in. SCooley138 (talk) 05:21, 16 July 2012 (UTC)

I've decided to move the entire section here until it can be thoroughly revamped. There are a number of commercial/trade names in this paragraph that are not capitalized. Moreover, the mere fact that a product contains a chemical does not make its name a synonym of the chemical name. --Nonstopdrivel (talk) 05:50, 19 September 2018 (UTC)
 * ==Synonyms==

Cetylpyridinium chloride is present in commercial products such as 1-palmitylpyridinium chloride, C16-alkylpyridinium chloride, 1-hexadecylpyridinium chloride, acetoquat CPC, aktivex, ammonyx CPC, cecure, ceepryn chloride, cepacol, ceprim, cepacol chloride, cetafilm, cetamium, dobendan, halset, ipanol, medilave, mercocet, merothol, pionin B, pristacin, pyrisept, and asept.

Another pointless article
Can I just repeat what I said about the article 'Poloxamer'

A completely pointless article
With apologies to those who contributed but unless you already know what a 'poloxamer' is you will be totally lost. I cannot see one sentence that would be comprehensible to a lay person.Cannonmc (talk) 15:03, 2 February 2016 (UTC)

Cannonmc (talk) 15:05, 2 February 2016 (UTC)

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