Talk:Chlorpromazine

Lunatic asylums
I don't think the term "Lunatic Asylums" is an appropriate term for psychiatric hospitals. It is not a factual term, but rather a derogatory one. It is not a neutral term either, as it has very negative connotations.
 * I agree and changed the wording to psychiatric hospitals. Cheers, PaddyM 19:25, 12 February 2007 (UTC)


 * What worries me is that someone editing wikipedia pages though that Lunatic Asylums was a appropriate term. Give him/her some thorazine. Annoying username (talk) 11:38, 16 June 2008 (UTC)

Uses
"Common uses" text just seems to be a lot of opinion.

The extensive use of single in double quotes in the first paragraph under "Common uses" did not improve my confidence in the information I was trying to look up. Is this necessary, or all of these sneer quotes? 66.92.73.217 07:27, 10 March 2007 (UTC)

It does seem to be a lot of NPOV or weasel words - I'm tempted to flag it as such. Alex 08:05, 3 April 2007 (UTC)

Promazine HCl vs. Chlorpromazine
Slightly off-topic, but there is some confusion over "Promazine hydrochloride" vs. "Chlorpromazine". Promazine HCl still has (at least) off-label uses. Could someone please clarify? Please see Talk:Promazine (Yes, I made the first talk entry, but I'm not the only one who's confused.) and contribute if you are able. Jedku (talk) 13:58, 5 December 2008 (UTC)

Confusion over name
I wanted to clarify same confusion over the brand names. In Canada we have Chlorpromazine, also known as Largactil. Stemetil is actually Prochlorperazine. This could be potentially error causing.

Thanks, Leanne RN —Preceding unsigned comment added by 139.48.25.60 (talk) 07:49, 30 January 2009 (UTC)

Citations?
For covering a drug that's been in use for nearly 60 years, this article has VERY few citations. Is there anybody who wants to tackle this problem? --Aurochs (Talk | Block)

Thorazine and Brain Rot
"Chlorpromazine (as chlorpromazine hydrochloride, abbreviated CPZ, is a highly toxic drug used to sedate and control patients, making them compliant while rotting their minds." Anyone know the story with this line in the introduction? Smells like vandalism to me.SignsFollowing (talk) 22:14, 17 June 2010 (UTC)


 * Smelly indeed, good catch. I have removed it. It was entered today @ 21:28, by . Be Bold, SignsFollowing! You can fix vandalism too! -- 220.101 (talk) \Contribs 23:31, 17 June 2010 (UTC)

Synthesis?
The German Wikipedia article describes a different synthesis (probably more recent). It's worth a look! Fvasconcellos (t·c) 18:21, 18 July 2010 (UTC)

Chlopromazine related to liver dysfunction
Chlopromazine is responsible for drug induced hepatitis. Namely causing cholestasis. — Preceding unsigned comment added by 41.132.107.218 (talk) 16:40, 13 September 2011 (UTC)

Poster Image
Could this article's poster image with the eye be disturbing for people with schizophrenia viewing this article? — Preceding unsigned comment added by 75.109.159.233 (talk) 06:14, 13 April 2012 (UTC)


 * @75.109.159.233
 * Hm. I think it could be offensive. But back in the 60's they didn't care. Pikachu.447 (talk) 08:10, 28 May 2024 (UTC)

History and manufacture
There is no section, or information, in the article regarding matters such as the original mamnufacturer, who got it through FDA etc etc. I think this information is as important and relevant as the scientific data. LookingGlass (talk) 07:00, 16 July 2012 (UTC)


 * The article specifies the year of discovery as 1951 but the Tricyclic Antidepressants article claims it was synthesized in December of 1950. I suppose "discovery" here may refer to publication; still seems a bit odd. Lewis Goudy (talk) 16:53, 29 August 2016 (UTC)
 * the lead was wrong. fixed it. Jytdog (talk) 18:26, 30 August 2016 (UTC)

The synthesis section
This section lists chemical building blocks for this pharmaceutical. I added links to these chemicals so someone can start and article on these chemicals. It is very important to get to the root of how these pharmaceuticals are made. Are they made from petrochemicals? 2602:306:C518:62C0:74DE:981B:CE5E:4DE0 (talk) 00:30, 23 July 2012 (UTC)

Chemical Straight Jacket
Thorazine is a drug with a storied history in the community at large. This should be included in this article. The term "Chemical Straight Jacket" is acknowledged in this college level textbook copyright 2012:

http://books.google.com.hk/books?id=ZBxeWu_r0R8C&pg=PA320&lpg=PA320&dq=chemical+straight+jacket+thorazine&source=bl&ots=ZeBhTsKEJF&sig=bf7HHo0cNUj6m8vajJgQF-Akr7Q&hl=en&sa=X&ei=urHuUNzzL8eHkgWglYBo&ved=0CGEQ6AEwCA#v=onepage&q=chemical%20straight%20jacket%20thorazine&f=false

Why shouldn't this Wikipedia article also reflect this popular perception?

116.55.67.205 (talk) 12:25, 10 January 2013 (UTC)

Psychdrugs synthesized from Benzene derivatives
Benzene is a petrochemical and a component of gasoline and is a carcinogen. Crude Oil is the ancient feces of the dinosaurs and it is true the medicine is made out of feces. 108.81.134.196 (talk) 01:23, 8 May 2013 (UTC)

chlorpromazine has been largely superseded by the newer atypical antipsychotics,
This is only the case in the affluent west. In many part of africa, it is the only affordable ant-psychotic and is also used in injectable form as a rapid tranquilliser, frquently combined with IV diazepam. — Preceding unsigned comment added by Saklein (talk • contribs) 10:21, 20 April 2014 (UTC) It's still common in United states used as a injection or a pill for psychotic disorders of the mind — Preceding unsigned comment added by A8v (talk • contribs) 10:00, 15 July 2015 (UTC)

US generic cost
Can somebody explain why the quoted cost of generic versions of this drug is much higher in the US than elsewhere? This seems nuts. Surely drugs which are out of patent can be freely traded worldwide, so the generic price should be more or less the same everywhere. I've noticed the same thing in other drug articles. Is this something to do with FDA licensing, or is it simple protectionism at the cost of the patient? --Ef80 (talk) 22:03, 24 March 2016 (UTC)
 * Talk pages are not a forum for general discussions. You might be able to find the answers you are looking for at Reference desk. Jytdog (talk) 22:51, 24 March 2016 (UTC)
 * No they cannot be freely traded world wide from what I understand (at least not among developed countries). A discussion of this would be useful. We have Prescription drug prices in the United States which I have not looked at. Doc James  (talk · contribs · email) 09:51, 25 March 2016 (UTC)
 * Jytdog, I have no axe to grind in this matter and am not American. I certainly don't want to discuss the subject on WP talk pages. The article currently quotes completely different generic prices for the US and elsewhere without explanation, and this needs clarification. --Ef80 (talk) 00:31, 26 March 2016 (UTC)

"Thorazine shuffle" redirection
I just wanted to point out that "Thorazine shuffle" redirects to this page, which never mentions "Thorazine shuffle" except in one note that states that "Thorazine shuffle" redirects to it. This is not particularly informative. 66.76.242.44 (talk) 22:53, 14 November 2017 (UTC)

Revert
Reverted edits are both WP:FRINGE and dated (outdated). Tgeorgescu (talk) 15:24, 15 March 2021 (UTC)

WP:PRIMARY studies are WP:MEDRS violations. See also WP:MEDDATE. Tgeorgescu (talk) 12:05, 16 March 2021 (UTC)


 * Yes the sources are really too old. As a first generation antipsychotic, it's also expected that there can be more serious side effects than with some more recent molecules, but the article already mentions them.  — Paleo  Neonate  – 12:16, 16 March 2021 (UTC)


 * True, I may even grant the point that that was true about medicines from the 1970s, but it is begging the question that it is true about medicines from 2020s. Tgeorgescu (talk) 21:03, 16 March 2021 (UTC)