Talk:Competitive inhibitor

I'm not sure that it is correct to call non competitive inhibition allosteric. Certainly they are similar with regard to the inhibitor (and activator in the case of allosteric enzymes) binding to a site other than the active site. however, allosteric mechanisms will change the Km whereas non competitive do not change the km. They are different classes of inhibition by definition. So I'm qualifying it. David D. (Talk) 04:48, 30 August 2005 (UTC)

Inhibitors can react too
The text states: &quot;In competitive inhibition, the molecule binds to the same active site as the normal enzyme substrate, but doesn't activate it.&quot; But some competitive inhibitors do activate the enzyme. E.g., the essential fatty acids Dihomo-gamma-linolenic acid, arachidonic acid and eicosapentaenoic acid are all mutually competitive inhibitors for cyclooxygenase and lipoxygenase. Other definitions on the web, such as here, don't put this restriction on. David.Throop 19:15, 17 February 2006 (UTC)