Talk:Complement component 4

Diagram & nomenclature issues
page is incorrect as is diagram, C2b binds to C4b to create the C3 convertase while the small diffusibl element c2a is the precursor of the C2 kinin. —Preceding unsigned comment added by 163.1.52.223 (talk) 19:44, 2 April 2008 (UTC)


 * The nomenclature of the C2 cleavage products is ambiguous. The older nomenclature mentions the larger, C4b binding fragment as C2a whereas the newer nomenclature calls uniformly all smaller complement cleavage product as "a" andt the larger cleavage products as "b".
 * The article refers "C4d" in lots of places that should be "C4b" —Preceding unsigned comment added by 80.98.12.50 (talk) 17:11, 29 September 2010 (UTC)
 * The article refers "C4d" in lots of places that should be "C4b" —Preceding unsigned comment added by 80.98.12.50 (talk) 17:11, 29 September 2010 (UTC)


 * I fixed the indenting of this current talk section and added a new talk page+section to the diagram on Commons: c:File talk:Complement pathway.svg
 * --No identd (talk) 13:40, 23 October 2018 (UTC)

WikiProject class rating
This article was automatically assessed because at least one WikiProject had rated the article as stub, and the rating on other projects was brought up to Stub class. BetacommandBot 16:25, 10 November 2007 (UTC)

Copyright problem removed
Prior content in this article duplicated one or more previously published sources. The material was copied from: http://ndt.oxfordjournals.org/content/18/11/2232.full). Copied or closely paraphrased material has been rewritten or removed and must not be restored, unless it is duly released under a compatible license. (For more information, please see "using copyrighted works from others" if you are not the copyright holder of this material, or "donating copyrighted materials" if you are.) For legal reasons, we cannot accept copyrighted text or images borrowed from other web sites or published material; such additions will be deleted. Contributors may use copyrighted publications as a source of information, but not as a source of sentences or phrases. Accordingly, the material may be rewritten, but only if it does not infringe on the copyright of the original or plagiarize from that source. Please see our guideline on non-free text for how to properly implement limited quotations of copyrighted text. Wikipedia takes copyright violations very seriously, and persistent violators will be blocked from editing. While we appreciate contributions, we must require all contributors to understand and comply with these policies. Thank you. Marchino61 (talk) 03:09, 14 June 2013 (UTC)

A large part of this stub article has been copied from an academic paper for which Oxford University Press owns the copyright. The paper is here: http://ndt.oxfordjournals.org/content/18/11/2232.full

Almost all the text of the article has been copied from the source cited above. Marchino61 (talk) 03:02, 14 June 2013 (UTC)

I have reverted it back to the version of 1st Sep 2008, which is the latest version I can find which does not contain the infringing text. Marchino61 (talk) 03:09, 14 June 2013 (UTC)

intro
this might be useful for the intro or any section--Ozzie10aaaa (talk) 15:14, 20 February 2016 (UTC)

SLE
While it's great that somebody finds it interesting that C4 may play a role in the pathogenesis of schizophrenia, could we please include something about the mechanism of C4 deficiency and SLE, given that's far more established? I mean, until the link with schizophrenia is established, it does not fall under clinical significance, whereas C4 levels are used in the evaluation of SLE

Confusing
Page contains too much history and human names in non-history parts. Tone sounds more like presenting findings from each study instead of describing the thing, which very quickly gets hard to read for decades of studies.

"Simple model" in lead is not very simple per Sekar et al. Similarities and differences between C4A/B (literally the first figure of Sekar et al) is not described in the article. --Artoria2e5 🌉 18:02, 1 May 2019 (UTC)