Talk:Connective tissue disease

A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity).[1]

Stickler syndrome
Should a mention of Stickler syndrome be added? I'm not an expert, but I apparently have Stickler syndrome, which my consultant told me caused my scoliosis, because it meant I had weak connective tissue, so it would seem to fit? Amphy (talk) 17:11, 20 May 2008 (UTC)


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Gone ahead and added it; I hope I did it right, and am correct in placing it here. Amphy (talk) 19:35, 16 June 2008 (UTC)

Seems to be based on one MDs knowledge 3 years ago
I have read the discussion. I would not presume to add to the Wiki, because perhaps I am just confused.

However, I am interested in why the word Fascia is neither used in the Article or referred to as a Further Reading topic. I am also interested in why Keloid growths are not mentioned or referred to for Further Reading.

Perhaps a statement should be made that this whole issue of connective tissue is a new, exploding area of research and as yet it is very poorly understood. TheLordSayeth (talk) 14:33, 27 September 2011 (UTC)

Current WP article omits to list or discuss certain collagen vascular diseases.
Acording to http://www.nlm.nih.gov/medlineplus/ency/article/001223.htm

Collagen vascular diseases include:

Ankylosing spondylitis

Dermatomyositis

Polyarteritis nodosa

Psoriatic arthritis

Rheumatoid arthritis

Scleroderma

Systemic lupus erythematosus