Talk:Dexmedetomidine

Wiki Education Foundation-supported course assignment
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Jrh334. Peer reviewers: WikiDS89.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 19:25, 16 January 2022 (UTC)

Comments from 2012
Change unique to unusual as relatively unique does not make sense. Ketamine and clonidine are also commonly used for sedation without respiratory depression. — Preceding unsigned comment added by 210.55.20.106 (talk) 00:04, 21 May 2012 (UTC)

Wikiproj Med
Hi guys! I will be re-organizing this article and adding more content. My goals are as follows:

1.) Describe Dex's medical uses, provide relevant pharmacology information (dynamics + kinetics), discuss side effects and interactions, and possible future directions.

I will be closely mirroring more robust pages discussing sedatives (propofol, benzos) and following their outline to make comparisons easy. I will also try my best to compare/contrast dex with other sedatives to provide context.

Please reply to this post with any helpful suggestions you may have!

Thanks! Jrh334 (talk) 19:56, 16 November 2015 (UTC)

Structural formula
in the drug-/chem-box is that of medetomidine, both of its enantiomers ((R)- and (S)-), as far as I remember, dexmedetomidine is only the (S)-enantiomer, so if someone would be so kind, it would be great to have the actual correct formula...--84.163.126.171 (talk) 22:31, 23 January 2008 (UTC)
 * This has been fixed. -- Ed (Edgar181) 14:29, 14 December 2010 (UTC)

Dexmedetomidine use in animals
Dexmedetomidine has the trade name of Dexdomitor. It is frequently used in dogs and cats both for sedation or as a pre-anesthetic. It is licensed for use in the United states by Pfizer Animal Health. In my experience, it is rarely used as a single agent. It has potent synergistic characteristics when used with an opiod. The benefits include deep sedation and profound analgesia. One major advantage of this combination is that it can be reversed with atipamazole. One concern is that pets will have a significant bradycardia and peripheral vasoconstriction. —Preceding unsigned comment added by Rdtenney (talk • contribs) 02:23, 26 June 2010 (UTC)

Loading dose
An anonymous editor has disputed the loading dose mentioned in the article. The article currently reads "1 mcg/mL loading dose", but the editor stated, "The loading dose is 1 mcg/kg not 1 mcg/ml". If anyone can clear up this discrepancy, that would be helpful. -- Ed (Edgar181) 14:28, 14 December 2010 (UTC)


 * Per wiki guidelines we don't include dosing of medications. Thus it was removed. --205.154.255.136 (talk) 17:23, 27 October 2015 (UTC)

Need advice
i am an ICU RN. I recd a pt today from PACU after back surgery. MD ordered Precedex to infuse at 9 cc/hr. No titration. Pt is on 2 liters. No artificial airway in place. Never had a pt on Precedex wasn't intubated and or being weaned from vent. Any thoughts? The rept I recd was that the Precedex is being used to potentiate the effect of the pain meds. Thanks, Nurse Nancy — Preceding unsigned comment added by 76.109.57.62 (talk) 02:31, 29 February 2012 (UTC)


 * This is not a forum for practical advice. JFW &#124; T@lk  18:27, 24 October 2012 (UTC)

Rapid tranq
Tiny study, but may get cited in secondary sources. For rapid tranquillisation in the emergency department, this stuff is not suitable. At least not in Australia. 10.1136/emermed-2011-200849. JFW &#124; T@lk  18:27, 24 October 2012 (UTC)

Peer Review:
The article is very comprehensive and the subgroups of information are all very relevant and pertinent to the main subject. I would maybe move the history portion to the beginning of the article as I think it would make more sense to layout the historical relevance of the drug prior to jumping into the more specifics of the medication. While the article is not non-medically friendly to read as other articles I think this is largely due to the subject and the fact that the audience for this article will likely be physicians and for this reason is very appropriate to have medical language and terms integrated into the article. I loved the abundant links to other pages as I think it aids in the learning of the audience and it is a great way to increase movement from one page to another seamlessly. — Preceding unsigned comment added by WikiDS89 (talk • contribs) 22:00, 18 November 2015 (UTC)

Merger proposal
This should be merged with medetomidine. Medetomidine is just the racemic mixture of dexmedetomidine and the inactive L-enantiomer (hence the name...dexmedetomidine). Source 1 Source 2

— Prof. Squirrel (talk) 02:00, 25 February 2018 (UTC)


 * Oppose We have separate articles for "omeprazole" and "esoomeprazole". They are sold as different meds, have different patents, have different prices, and sometimes have different side effects. Doc James  (talk · contribs · email) 05:22, 25 February 2018 (UTC)
 * Oppose The effects etc. are different in animals too. DferDaisy (talk) 17:09, 18 March 2018 (UTC)