Talk:Dopamine/GA1

GA Review
The edit link for this section can be used to add comments to the review.''

Reviewer: Seppi333 (talk · contribs) 16:28, 13 March 2016 (UTC)

Criteria
 Good Article Status - Review Criteria   		A good article is&mdash;  :
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Discussion

 * In Dopamine, the following text sort of makes it sound like only D2 long/short receptors are present in a DA synapse: Once in the synapse, dopamine binds to and activates dopamine receptors. These can be the D2Lh type, located on the postsynaptic target cells or the D2Sh autoreceptor type located on the membrane of the presynaptic cell. Might be worth rephrasing this.  Seppi  333  (Insert 2¢) 17:16, 13 March 2016 (UTC)
 * I don't know anything about that and don't know why it matters -- my preference would be to delete that sentence. Is there a reason why it needs to be there? Looie496 (talk) 15:40, 14 March 2016 (UTC)
 * Not really since the DA synapse illustration shows what DA receptors are located on the axon terminal/dendrites, but I clarified the statement anyway and added a ref.  Seppi  333  (Insert 2¢) 21:48, 15 March 2016 (UTC)


 * This statement in Dopamine should probably be cited: The dopaminergic areas they identified are the substantia nigra (groups 8 and 9); the ventral tegmental area (group 10); the posterior hypothalamus (group 11); the arcuate nucleus (group 12); the zona incerta (group 13) and the periventricular nucleus (group 14).  Seppi  333  (Insert 2¢) 17:23, 13 March 2016 (UTC)
 * That's covered by the previous cite, but I've replicated it for clarity. Looie496 (talk) 15:40, 14 March 2016 (UTC)
 * Thanks.  Seppi  333  (Insert 2¢) 21:48, 15 March 2016 (UTC)


 * This is somewhat disconcerting. I'll pass the article even if that isn't covered, but it's worth noting that a dopamine dysregulation syndrome is literally just a drug-induced behavioral addiction which isn't specific to Parkinson's disease or PD drugs. The text described it as a disorder involving motor dysfunction like PD.  Seppi  333  (Insert 2¢) 01:14, 14 March 2016 (UTC)
 * Can you give some guidance on how to handle this? Our article on DDS seems to describe it entirely in the context of PD treatment.  I'm not sure where to go here. Looie496 (talk) 15:40, 14 March 2016 (UTC)
 * I covered this in 2 sentences at the end of the PD section; I've covered the DDS in several addiction-related articles, so I just used sources that I've used elsewhere.  Seppi  333  (Insert 2¢) 21:48, 15 March 2016 (UTC)

Let me add my thanks for taking on this review. I'll try to respond as quickly as I can to any points raised here. Looie496 (talk) 15:40, 14 March 2016 (UTC)
 * No worries. Looks good with these points addressed.  I think this article is definitely GA status now, so I'm going to go ahead and promote it.  Seppi  333  (Insert 2¢) 21:48, 15 March 2016 (UTC)
 * Great work on this article. It's been much improved over the last couple of years and it's good to see it brought up to GA. T.Shafee(Evo&#65120;Evo)talk 04:03, 10 June 2016 (UTC)