Talk:Encephalopathy

Source
Part of this article is adapted from the public domain U.S. NINDS document "NINDS Encephalopathy Information Page" located at 

Types
[mailto:brewhaha@freenet.edmonton.ab.ca]: I added the part about Alzheimer's and CJD. The former may not be transmissible, and it's certainly a neurodegenerative disease. 216.234.170.74 15:12, 31 July 2006 (UTC)

This article on inflammation in Alzheimer's and prion diseases shows that the distinction between Alz and human prion disease may be arbitrary. It seems to be a review, because it talks of a great many things that I find hard to put into one experiment. 216.234.170.74 15:51, 31 July 2006 (UTC)

PRES posterior reversible encephalopathy syndrome - I didn't stabilise for 3 days, 12 cases in medical history before me, nothing online on any browser, even the brain charities I emailed never heard of it. Why did I almost die from the most Excruciating brain-ripping pain and blindness, swelling until they flew someone 3 days later to diagnose, 12 cases in medical history he told my family, yet can't even find research? Also I am constantly reminded that stress could trigger it to happen again which would be fatal. There's no support except for hie and encephalitis who won't support an adult PRES sufferer. Unbelievable really in this day and age, it was only 2 yrs ago Morrigan81 (talk) 08:13, 3 October 2022 (UTC)

Introduction
Now that I look at the lead section, "non-specific" leaps out at me. Encephalopathy literally means "Disease of the pENIS". 216.234.170.74 15:20, 31 July 2006 (UTC)

Anthropocentrism
This article deals only with encephalopathy in humans. Since bovine spongiform encephalopathy is much more familiar to lay people than any of the other forms of encephalopathy listed, this amounts to a grave imbalance. And why, for that matter, isn't CJD listed, since it is the human form of this encephalopathy of cattle?

Also There are severe causes of encephalopathy Should this be "several causes"? Ireneshusband 18:01, 17 November 2006 (UTC)

severe causes?
In the section listing what appear to be 4 types of encephalopathy, there's a sentence at the top reading, 'There are severe causes of encephalopathy.' The section does not appear to list causes, but types, and I don't understand why 'severe' is in the sentence. Shouldn't it be something like 'There are several types of encephalopathy'? Mathtinder 02:29, 25 November 2006 (UTC)

Hypertension BP 190/130 Morrigan81 (talk) 08:09, 3 October 2022 (UTC)

Intro
I fixed the poor writing of the second paragraph of the introduction, but I have realized that it elucidates nothing, defeating the purpose of a hypothetical example. Therefore, I am removing it, since it is extremely long-winded, and the point of an introduction is to concisely introduce a topic. If anyone cares to prune it and reintroduce what is left, here is the text: A descriptive example may clarify the distinctions between these entities. An elderly man with Alzheimer's disease, manifested by mild dementia (forgetfulness and impaired judgment) develops pneumonia, a severe infection. He manifests depressed consciousness, myclonic jerks, jactitation (restless tossing in bed, picking at things), and Cheyne-Stokes respirations (rhythmic increase and decrease in respiratory frequency and depth). These are symptoms (not exclusively) of toxic-metabolic encephalopathy. Because of the severity of the patient's illness he is admitted to the intensive care unit, intubated with an endotracheal tube, mechanically ventilated, and sedated with medications. After a week his infection is cured and he is extubated and breathes independently. At this point he sleeps during the day and is awake and agitated at night, has hallucinations and alternating periods of lucidity and confusion, and manifests paranoia. This is delirium, arising from multiple previous insults (reduced baseline mental faculties, infection, psychoactive medications, altered environment, etc.). With cessation of psychoactive medications, enforcement of normal day/night dark/light cycles, and frequent, gentle re-orientation to his surroundings, his confusion clears, leaving him mentally with his previous baseline dementia.

--♦♦♦Vlmastra♦♦♦ 04:28, 4 November 2007 (UTC)

Hypoxic ischemic encephalopathy
should HIE be inclueded in this page, it is a term that is commonly used in medicine yet it is not on this page. should it be inclued?--Mygodshesfat (talk) 19:51, 22 April 2008 (UTC)

Copied
Some info on this site is copied from the NINDS site on Encephalopathy! Is this considered plagiarism. --Edward130603 (talk) 02:23, 24 February 2009 (UTC)

MRI
The MRI is pretty, but has nothing to do with encephalopathy. It should probably go away. —Preceding unsigned comment added by 75.15.115.174 (talk) 06:28, 17 May 2009 (UTC)

Agreed. I have removed the infobox containing the image. Perhaps it should be restored with a different image, or perhaps someone can explain why that MRI image had particular relevance to an article on encephalopathy. Rfontana (talk) 07:59, 25 June 2009 (UTC)

Prion diseases
I deleted the statement that prion diseases are invariably infectious - this is simply not true. The unique feature of prion diseases is that they can be infectious, spontaneous or hereditary. I would suggest deletion of mention of prion diseases in that section for a more conventional encephalopathy - while prion diseases may be very exciting and cutting edge, they don't make for good comparisons. 82.46.212.111 (talk) 23:38, 17 July 2010 (UTC)

Hepatic encephalopathy?
Hepatic encephalopathy (HE) was not listed, and is typically discussed in the context of specific toxic molecules like ammonium, resulting from TIPSS procedure. Should HE not be listed as a distinct form? — Preceding unsigned comment added by 130.238.224.23 (talk) 17:04, 18 January 2018 (UTC)

Toxicity from psychotropic medications
This section has no sources indicated.

> All therapeutic interventions are double-edged swords with benefits and adverse effects, and pharmacotherapy is not an exception.[...]

This is not the way one writes encyclopedic material. "double-edged swords" It's not just using unencyclopedic wording, but it's also unsourced. Gamma1138 (talk) 19:20, 23 July 2023 (UTC)