Talk:Familial Mediterranean fever

note
With regard to ethnic indicators, the cited article is not the best one, and the current description is misleading. Recent research suggests that Ashkenazi Jews are, in fact, carriers of FMF at the rate of approximately 20 percent. See "Mutation and Haplotype Studies of Familial Mediterranean Fever Reveal New Ancestral Relationships and Evidence for a High Carrier Frequency with Reduced Penetrance in the Ashkenazi Jewish Population", Am. J. Hum. Genet. 64:949–962, 1999, .

Metaraminol Provocative Test (MPT
I have not found this recommended in any of the current literature. Ben-Chetrit et al have presented contradictory findings in 1990 in a letter to the editor (Lancet). There does not seem to have been much discussion on the subject since.

Anakinra
Ann Intern Med this week - Anakinra helps if colchicine fails or is poorly tolerated. JFW | T@lk  22:37, 4 June 2007 (UTC)


 * Or rilonacept 10.7326/0003-4819-157-8-201210160-00003. Same journal incidentally. JFW &#124; T@lk  23:20, 17 February 2014 (UTC)

Review
- Br J Haematol JFW | T@lk  19:40, 12 August 2009 (UTC)

Added
This was added:
 * Some research has been done to investigate the connection of amyloidosis and Familial Mediterranean Fever, and studies have found that an important variation in this particular complication arises from the Met694Val and Val726Ala mutations. More specifically, individuals who are homozygous for Val726Ala seem to be protected from developing amyloidosis, while those who are homozygous for Met694Val or compound heterozygous for Val726Ala are susceptible. However, there is evidence to suggest that those who are heterozygous for Val726Ala may respond well to regular treatment with colchicine, thus preventing them from developing renal amyloidosis.

This needs a secondary source. JFW &#124; T@lk  10:58, 6 December 2020 (UTC)

Unsourced anecdotal symptoms
I recently removed some unsourced information added by a Wikipedia user who personally experiences familial Mediterranean fever. I was unable to find any external source to substantiate their experiences, but have added a message to their talk page to prompt for further information. If anyone feels this should be reinstated, just let me know so we can avoid a removal war! Guidance is available on which sources are appropriate. --AlexVojProc (talk) 22:55, 19 May 2022 (UTC)

"Epidemiology of Familial Mediterranean fever in the United States of America" listed at Redirects for discussion
The redirect [//en.wikipedia.org/w/index.php?title=Epidemiology_of_Familial_Mediterranean_fever_in_the_United_States_of_America&redirect=no Epidemiology of Familial Mediterranean fever in the United States of America] has been listed at redirects for discussion to determine whether its use and function meets the redirect guidelines. Readers of this page are welcome to comment on this redirect at  until a consensus is reached. Fram (talk) 08:46, 6 November 2023 (UTC)