Talk:Genetics of aging

Sourcing problems
The following was added today, and there is unsourced content and sources that fail WP:MEDRS. This sort of thing has a lot of hype around it and sourcing needs to be very high quality for this.


 * DNA repair and extended longevity

Many authors have noted an association between defects in the DNA damage response and premature aging. If a DNA repair protein is deficient, unrepaired DNA damages tend to accumulate. Such accumulated DNA damages appear to cause features of premature aging (segmental progeria) (see Defects in DNA repair cause features of premature aging).

On the other hand, genetic alterations that increase DNA repair or decrease damage in DNA, may cause extended longevity. Table 1 lists DNA repair proteins whose increased expression is connected to extended longevity.

-- Jytdog (talk) 17:34, 7 July 2017 (UTC)