Talk:Granuloma

Untitled
this page is too technical/medical, it is hard to understand from the viewpoint of a scientific undergraduate rather than a medical student, could someone ammend this please.
 * I agree. I'm tagging the page as such. RobertM525 00:20, 24 May 2006 (UTC)

Can you write something about sarcoidal granuloma? Thanks. --Eleassar777 20:41, 21 Mar 2005 (UTC)

non-necrotizing versus non-caseating
The more precise terminology is "non-necrotizing" or "necrotizing rather than "non-caseous or "caseous," as Yale Rosen, M.D. explained: "The use of the terms "caseating" and "non-caseating" to describe the microscopic appearance of granulomas, although prevalent, is inappropriate since the term "caseous" applies only to the grossly visible cheese-like appearance that may be associated with necrotizing granulomas, necrotic neoplasms and other types of necrotic lesions. There is no typical microscopic appearance that corresponds to the gross appearance of caseation." See URL http://www.granuloma.homestead.com/morphology.html


 * You posted an URL for an image, but it contained a DNS. Could you provide a better link with address? JFW | T@lk  10:36, 26 Jun 2005 (UTC)

Aschoff cells
You referred that Aschoff cells (and thus anitschkow cells) are derived from macrophages, however, there is alot of controversy over their true origin. There are those that defend that they are cardiac histocytes, nonetheless, others defend that they derive from muscle cell, others defend that they are derived from diseased lymphatic vessels and there are yet those that believed they are derived from nerves. —Preceding unsigned comment added by Aschoff anitschkow (talk • contribs) 04:35, 10 February 2008 (UTC)

Hypergranulation definition needed
Could someone please define Hypergranulation? The word is mentioned in the article Ingrown nail, and links here, but there is no mention as to what it actually is. Thanks. Stephen! Coming... 16:48, 13 January 2009 (UTC)

Granulation tissue is a reaction to injury (such as a simple cut on the skin or an ulcer in the stomach). In simple terms, it is what's known as "proud flesh", a red, grainy-looking area of healing at the site of an injury. Under the microscope, it consists of a combination of small blood vessels (capillaries), inflammatory cells (lymphocytes) and scar tissue (fibroblasts). In pathology, there is no such thing as "hypergranulation" tissue. Perhaps that term is being used to describe especially prominent granulation tissue. Finally, there is nothing common between "granulation tissue" and "granuloma" except that they sound similar. —Preceding unsigned comment added by

Syphilis
Syph (T. pallidium) can cause gumma's which are granulmatous. 72.90.71.90 (talk) 14:47, 29 March 2009 (UTC)

Splenic Granuloma
If someone is diagnosed with a splenic granuloma, is there one specific cause for it or is it a symptom of any number of things?23.16.152.103 (talk) 07:41, 30 October 2012 (UTC)BeeCier

Clumsy hatnote
" For the Interstitial granulomatous drug reaction, see Interstitial granulomatous drug reaction."

I feel the wording needs to be improved, but I have no suggestions how. If someone else thinks of a better way to phrase this please do so. Lesion ( talk ) 20:57, 14 April 2013 (UTC)

Literature to be added

 * Silva Miranda, M.; Breiman, A.; Allain, S.; Deknuydt, F.; Altare, F. The tuberculous granuloma: An unsuccessful host defence mechanism providing a safety shelter for the bacteria? Clin. Dev. Immunol. 2012, 2012.
 * Paige, C.; Bishai, W.R. Penitentiary or penthouse condo: The tuberculous granuloma from the microbe’s point of view. Cell. Microbiol. 2010, 12, 301–309.
 * Shaler, C.R.; Horvath, C.N.; Jeyanathan, M.; Xing, Z. Within the Enemy’s Camp: Contribution of the granuloma to the dissemination, persistence and transmission of Mycobacterium tuberculosis. Front. Immunol. 2013, 4.

--SCIdude (talk) 08:33, 26 January 2019 (UTC)