Talk:Guillain–Barré syndrome/Archive 2

Treatment section - "should fall on the family"?
Not an editor here, but this paragraph of the Teatment section sounds like opinion to me, and is unsourced:

A fundamental part of hospital treatment should fall on the family. As hospitals reduce healthcare it becomes impossible to care for patients around the clock. Patients that reach total paralysis are unable to signal or call for help and this is where family care becomes so important. Family members provide care and support that patients desperately need and medical staff sometimes don't understand or are unable to provide. Due to inactivity the body loses tone and flexibility. It's suggested that learning Range of Motion from medical staff and using stretches and keeping the joints pliable will aid the patient to recover sooner than letting them lay in a vegetative position. This also helps with circulation and the onset of bedsores. Bedsore prevention mattresses provide comfort to the patient if the family is unable to maintain 24 hour care. This is important because hospital recovery from Guillain-Barre can last from weeks to months. —Preceding unsigned comment added by 140.244.105.190 (talk) 20:03, 26 February 2008 (UTC)

I thought the same and have gone ahead and removed this paragraph. "As hospitals reduce healthcare" - Which hospitals? What type of healthcare? In what regions/ countries? "It's suggested" - by whom? "should fall" is normative.

While I would be happy to see a statement about the beneficial effects of non-clinical provision of care and support to Guillain-Barre patients, this paragraph is not acceptable. If anyone wants to rewrite it or put something in its place that would be great. Varchoel (talk) 15:27, 8 May 2008 (UTC)

Differential diagnosis
Perhaps Conversion Disorder could fall under this category?192.88.165.35 (talk) 22:30, 22 October 2008 (UTC)


 * No. Why? JFW | T@lk  01:55, 16 December 2008 (UTC)

Miller-Fischer
Redirected "Miller-Fischer" and "Miller Fischer" here. Anyone please feel free to make seperate pages, but as long as these don't exist... —Preceding unsigned comment added by Pizzaman79 (talk • contribs) 12:40, 21 November 2008 (UTC)

Pathophysiology
The Pathophysiology section has no citations and made some rather dubious statements which conflict with NPOV (particularly the sentence that goes 'Vaccines, broad-spectrum antibiotics, and "virus in stealth" ... are themselves an onslaught on the immune system...'). I've deleted this sentence and the one which follows, and added a note requesting citations. Procrastinator supreme (talk) 22:05, 2 February 2009 (UTC)

There are now something like five citations in this section, so I have removed the Wiki warning about lack of citations.Jack B108 (talk) 11:16, 21 August 2009 (UTC)

Pronunciation
I am puzzled by the first English pronunciation given: "in English pronounced /ˈɡiːlæn ˈbɑreɪ/[3], /ɡiːˈæn bəˈreɪ/,[4]". Ok, English speakers make a mess of the vowels when they try to pronounce a French name, but they get a G right. So what is the ˈɡ? I don't see that symbol on the IPA for English page. The source cited says "(pronounced Ghee-lan Bar-ray)". My guess is that someone has taken "Gh" to indicate a voiced velar fricative. I don't think that was the intention, I think it just indicates an ordinary g sound, with the h there to keep the g hard.

Unless someone has a different explanation, I propose replacing that ˈɡ by a g. Maproom (talk) 15:07, 9 February 2009 (UTC)


 * Done. Maproom (talk) 22:59, 19 February 2009 (UTC)


 * ˈɡ is two symbols: a stress mark and a "g" (voiced velar plosive). The IPA for English page has the stress marks (high vertical line for primary stress, low vertical line for secondary stress) near the bottom of the page, the box marked "Stress". (Voiced velar fricative would be ɣ.) -- pne (talk) 19:39, 17 August 2012 (UTC)

Signs and Symptoms
The first line of the following passage concerns me. I am not a neurologist, but this seems to be a statement that needs to be made elsewhere or toned down, as it is probably not how most neurologists would describe the paralysis to their patients (is it??):

''Acute paralysis in Guillain-Barre syndrome is usually related to sodium channel blocking factor in the cerebrospinal fluid. Morbid and iatrogenic events involving IV salt and water may occur unpredictably in this patient group, resulting in SIADH. SIADH is often the first symptom of Guillain–Barré syndrome. Sodium overload is almost always iatrogenic. Rapid correction of hyponatraemia can cause central pontine demyelination.[citation needed]''

I thought the paralysis was generally described as caused by extensive peripheral nerve damage (myelin loss and even axonal destruction). There are studies of high-quality that mention something about relation between paralysis and Na+ channel blocking in the cerebrospinal fluid, but this seems like a side issue and too detailed for a Wiki entry, IMHO. And again too much jargon. Comments? Neuro`s in the house?Jack B108 (talk) 23:28, 19 August 2009 (UTC)

I had Gillian Barre Syndrome in 1982
I was walking with my husband in Atlantic City and I clasped to the floor. My legs were just trembling and it felt like needles were just pinching me. We went back home that same day to New York. It just got worse and I was taken to the doctors office. He said it could be Mono and I was like isn't that a kissing disease?? I can't lift my left to walk I have no feeling in my arms and it's getting worse. It can't be just Mono we all said. Once I was admitted to the hosiptal I became a ginny pig to all the doctors. As I was in a wheel chair they pinch me with needles every where to see if I had a reaction to the pain. I had so many spinal taps done and I was so scared that I would stay paralized. Thanks Be to God between Prayers and Godspell music and tapes on Sermons. I was able to leave the hospital in less than a month. They couldn't give me any medicine I slept with patches on my eyes because they wouldn't close and I had no tears. They had to put tear drops in my eyes daily. My hair was like Brillo we couldn't get the knots out. My body was just died no movement at all. The doctor said if I could wiggle my toes he would send me home. Well I work hard on that since my feet had to be held up with a board at the end of my bed. I had no reflexes I had no control of my body it was the worse 2-3 months of my life. Well that year my body was cleansed of every thing including my birth control bills and in 1983 I had my first daughter. She is healthy Thanks Be to God and so are my other two girls. I have 3 healthy and beautiful girls. I still do not have my relexes back my face still feels stift but I'm healthy. BUT, now I'm feeling a little weird again and I was wondering can this virus come back? I took this sleeping pill about two weeks ago Abien I believe is the name. I felt and walk like I was drunk and I had no control of my body. I kept falling a sleep while talking it was horrible. Then just this past Sunday we went to the Redskins game and we did a lot of walking. We just about ran up 2 flights of a very long ramp. My thighs hurt so much and I still have this numbness in my thighs. My face has been feeling tight the last few weeks and I'm now thinking could this virus be coming back??? I'm going to call my doctor to get check out but what will they look for?? Will she be able to know if it's coming back. I feel like I'm walking a little bit like I did in 1982 and so I'm worried. Does any one have any helpful answers?? I pray they can find a cure for this. It's just an ugly disease just like Cancer. Thank you for reading my story on the worse 6 months to a year of my life. —Preceding unsigned comment added by 205.229.101.10 (talk) 21:31, 17 November 2009 (UTC)

Epidemiology needs more
It shouldn't just be about pregnant women and neonates. If it is it pregnant women who tend to get this syndrome, some supporting data would help. How about starting by moving the incidence from the first paragraph to here. Some info (expert needed) about the age groups that tend to suffer from this the most would be nice. —Preceding unsigned comment added by Imogenne (talk • contribs) 19:48, 18 December 2009 (UTC)

Countries with especially high rates
Should countries with especially high rates of Guillan-Barré syndrome be noted? My family alone knows four sufferers of this syndrome (my Dad being one of them, but he recovered very well)... And I'm pretty sure we don't know 200,000-400,000 people... So, is that just us, or my country (NZ)? Gott wisst (talk) 06:05, 2 April 2010 (UTC)

Image of notable case
As this is an image of a notable case it belongs in that section. Doc James (talk · contribs · email) 16:19, 1 September 2010 (UTC)
 * The image says nothing about the condition. Doc James  (talk · contribs · email) 17:58, 1 September 2010 (UTC)
 * I've just moved the image concerned to the appropriate section. As you correctly say it says nothing about the condition itself and you have to read to the bottom of the article to reach that particular text.StevieNic (talk) 08:36, 3 September 2010 (UTC)
 * Thank you. Doc James (talk · contribs · email) 08:48, 3 September 2010 (UTC)

Chinese study on 90 million doses of H1N1 shows lower than background Guillain-Barre Syndrome rate
http://www.vaccinetimes.com/chinese-study-on-90-million-doses-of-h1n1-shows-lower-than-background-guillain-barre-syndrome-rate/ —Preceding unsigned comment added by 109.124.166.232 (talk) 16:56, 22 March 2011 (UTC)

IVIG insufficient
Standard dose IVIG doesn't always cut it - do we need more? 10.1007/s10875-010-9407-4 JFW &#124; T@lk  13:36, 28 November 2011 (UTC)

Undue weight to influenza vaccination link?
Seems that although there was clearly a link in 1976, but not substantiation of increased risk in recent years....a huge part of the article goes over this in detail and it seems to make the article lopsided. Thoughts on paring down this section? Wawot1 (talk) 03:30, 21 December 2011 (UTC)


 * I have no problem with finding two or three major sources and possibly some public health announcements, and rewriting the entire section. Perhaps a useful source would be one that discusses what to do with regards to influenza vaccination in someone who has already had an episode of GBS! JFW &#124; T@lk  20:59, 21 December 2011 (UTC)


 * I lopped off some text, added a few references, and tried to summarize this in a concise way - hopefully haven't ruffled any feathers.  Wawot1 (talk) 01:24, 22 December 2011 (UTC)

FDR
If Franklin Roosevelt had GBS rather than polio, why didn't he recover? — Preceding unsigned comment added by 66.136.146.25 (talk) 05:59, 27 August 2012 (UTC)


 * Not all GBS leads to full recovery, particularly the axonal subtype. JFW &#124; T@lk  15:49, 27 August 2012 (UTC)

COI clean-up
I've removed an insertion by what appears to be a COI account primarily devoted to including links to articles by a doctor of the same name. If uninvolved editors find this information to be a useful addition to the article, however, please feel free to restore. -- Khazar2 (talk) 16:45, 17 December 2012 (UTC)