Talk:Hyperparathyroidism

Wiki Education Foundation-supported course assignment
This article was the subject of a Wiki Education Foundation-supported course assignment, between 13 January 2020 and 27 April 2020. Further details are available on the course page. Student editor(s): Armansawhney.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 00:09, 17 January 2022 (UTC)

Beware
There is a small chance that I will attack this article, armed with last week's Lancet review. JFW | T@lk  19:00, 26 July 2009 (UTC)


 * 2011 review  Doc James  (talk · contribs · email) 15:20, 11 March 2011 (UTC)


 * . Nuclear medicine imaging guidelines (Europe). JFW &#124; T@lk  11:23, 27 November 2011 (UTC)

Lancet
10.1016/S0140-6736(17)31430-7 JFW &#124; T@lk  21:17, 13 January 2018 (UTC)

Lead
, your sentence in the lead seeking to distinguish between primary and secondary does not quite succeed. It is obscure; to state that primary is due to the the glands "inappropriately making too much PTH" does not sufficiently distinguish primary from secondary, as in both cases the glands are making more PTH than is appropriate. In fact, our article on secondary says that it "refers to the excessive secretion of PTH" by the glands. In both cases the amount produced is "inappropriate", to use your term. It would be clearer to distinguish between excessive production caused by a disorder in the gland and excessive production caused by factors from outside the gland. It is a simple distinction: internal vs. external cause. That is what we should state. Regards, Kablammo (talk) 03:58, 14 December 2018 (UTC)
 * User:Kablammo excellent point. How about "This occurs either from a disorder within the parathyroid glands (primary hyperparathyroidism) or disorder outside the parathyroid glands (secondary hyperparathyroidism) resulting in them making too much PTH."? Doc James  (talk · contribs · email) 10:53, 14 December 2018 (UTC)
 * Great! Thanks.  Kablammo (talk) 12:35, 14 December 2018 (UTC)

High calcium resulting in symptoms
It is not just long term high calcium but also acutely high calcium that can result in symptoms per the ref "Symptoms and clinical signs often relate to chronic hypercalcaemia rather than to increased parathyroid hormone.13,14 In the 20–30% of symptomatic patients, nephrolithiasis is the most common symptom. Overt skeletal disease is rare, but osteoporosis with related fracture is increasing.15 Acute hypercalcaemic crisis with nephrogenic diabetes insipidus and dehydration is most likely in patients with a concentration of albumin-adjusted calcium greater than 3·0 mmol/L."

In other words sometimes symptoms are due to long term high blood calcium, sometimes they are due to acutely really high blood calcium. So saying it is just long term high calcium is incorrect. That is why they use the term "often". Doc James (talk · contribs · email) 14:22, 18 April 2019 (UTC)


 * Thank you for this quote. I think we agree that acute hypercalcemia results in completely different symptoms than chronic hypercalcemia. The symptoms listed in this article are due to long-standing hypercalcemia; there is no mention of acute hypercalcemia or its symptoms. I will add the symptoms of that entity to the Lead and see if this is a satisfactory resolution to you. Regards, IiKkEe (talk) 14:51, 18 April 2019 (UTC)
 * Was already summarized just one sentence down in "Others symptoms may include bone pain, weakness, depression, confusion, and increased urination" Doc James  (talk · contribs · email) 19:14, 18 April 2019 (UTC)

NICE guideline
Here JFW &#124; T@lk  21:01, 29 March 2021 (UTC)

Wiki Education assignment: WikiProject Medicine Fall 2023 UCF COM
— Assignment last updated by Emlitt (talk) 21:44, 26 October 2023 (UTC)

Suggest the following possible changes:
 * I will expand on the causes of Hyperparathyroidism
 * I will expand on the mechanism section and include the role of PTH the the mechanism of action
 * I will add a regulation of PTH section
 * I will expand on the diagnosis section
 * I will add a section on embryology
 * I will add to the classification section of primary, secondary and tertiary hyperparathyroidism
 * I will add more to the differential diagnoses section