Talk:Hypertriglyceridemia

Omega 3
I also found this paper interesting Omega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance — Preceding unsigned comment added by User: (talk • contribs)


 * True, but contradicted by some other sources. JFW &#124; T@lk  12:49, 16 September 2012 (UTC)

Exercise
It would be good, if reliable citations are available, to say in the article whatever is known about whether exercise is helpful in treating this condition. If nothing for sure is known either way,I say it would be of value to say that, at least.--Richard L. Peterson71.198.176.141 (talk) 06:12, 14 September 2009 (UTC)


 * I might be able to add something on the basis of the new guideline, but in the absence of data from there we should limit ourselves to WP:MEDRS-compatible secondary sources. JFW &#124; T@lk  12:49, 16 September 2012 (UTC)

Review
In addition to the new Endocrine Society guideline, perhaps this review might be useful: 10.1503/cmaj.060963 JFW &#124; T@lk  15:19, 12 September 2012 (UTC)


 * Another one about pancreatitis, but I can't retrieve the article: 10.1097/MOL.0b013e3283319a1d. JFW &#124; T@lk  23:00, 13 September 2012 (UTC)

Atherosclerosis
I have removed the following, because it is likely to be conflicting with the CPG paper, or at least will need recalibration:

Since triglycerides are not a component of the atherosclerotic plaque, it is not intuitively obvious whether hypertriglyceridemia promotes atherosclerosis. Numerous studies (summarized in references ) have examined the relationship between hypertriglyceridemia and atherosclerosis with a definitive answer still not apparent. In large part, the conflicting results reflect whether various other relevant risk factors for atherosclerosis were examined and taken into account. Specifically, the following are all risk factors for atherosclerosis and all are also associated with (not necessarily in a causal way) hypertriglyceridemia: (list remains on the page)

In other words, any study purporting to demonstrate an association of hypertriglyceridemia and atheroslerosis must not only have controlled for the classic atherosclerosis risk factors but also for the more recently recognized risk factors such as insulin resistance, levels of small, dense LDL, and apoB levels. The relationship among hypertriglyceridemia, atherosclerosis, and apoB is particularly instructive. Specifically, those forms of hypertriglyceridemia associated with high levels of apoB, but not those associated with low levels of apoB, are associated with atherosclerosis.

Wondering how to approach this. JFW &#124; T@lk  12:49, 16 September 2012 (UTC)

European Atherosclerosis Society Consensus Panel
10.1016/S2213-8587(13)70191-8 in Lancet Diab Endocrinol. JFW &#124; T@lk  10:53, 27 December 2013 (UTC)

Endocrine Rev
10.1210/er.2014-1062 Genomic approach. JFW &#124; T@lk  23:40, 31 January 2015 (UTC)