Talk:Immunoglobulin class switching

Dead External Links?
Not sure if it is just my dodgy internet connection, but are the final three external links now dead-links? Version of the page as I write this: http://en.wikipedia.org/w/index.php?title=Immunoglobulin_class_switching&oldid=553640645 Cheers, 124.149.51.148 (talk) 11:02, 14 May 2013 (UTC)
 * I don't know if anyone picked this up in between, but (again?) most external links are dead. I removed them. Lisiduna (talk) 19:59, 6 November 2015 (UTC)

significance?
What is the function of this switching with regard to the immune response? 108.48.193.229 (talk) 05:03, 21 October 2014 (UTC)

That depends on the type of switch, location inside the body and other factors. For example, class switching to IgE can increase mast cell degranulation which can lead to allergic reactions. — Preceding unsigned comment added by 86.88.224.29 (talk) 12:48, 4 April 2015 (UTC)