Talk:Interactome

Untitled
Disclaimer: I am not a biologist. It seems implicit in this page that an Interactome, perhaps like a genome, is a body of information about some particular species. If so this should be made explicit.

If this is so the following question is begged: If protein X impacts protein Y in species A, why does it not impact it in species B?

Hopefully there is a short list of such known or proposed mechanisms and the list should be mentioned. I have recently heard a theory, whose name I have forgotten, that introns in the DNA (near the expressor gene of the impacted protein) may control such impact and thus are interactomes inherited.

76.220.201.192 (talk) 02:55, 10 June 2008 (UTC)

Yes agreed 76.220.201.192 biology is of course not limited to PPIs ( Protein- Protein interactions ). The genome only represents proteins, but these proteins represent information about the environment ; so why are PPIs necessarily more important than this other information BillO&#39;Slatter (talk) 03:51, 26 June 2008 (UTC)

Genetic interaction networks confusion?
The third paragraph of this section talks about "the interactome" as if there were only one. It talks about "it" being incomplete as of October 2010. But the paragraph never describes WHAT interactome it's referring to. I originally thought that it was referring to the interactome in the prior paragraph related to Budding yeast, but that's not very clear. And, given that the paragraph has only one citation (that doesn't work), I can't really find a way back to the original source material. SeanAhern (talk) 17:53, 1 October 2012 (UTC)

The same thing is true of the "Using the interactome" section. It also talks about "the interactome" as if there were only one. At first, I assumed that it was talking about the complete interactome of the human body. But the source material (at least the first one) talks about yeast. How should we clarify this? SeanAhern (talk) 17:53, 1 October 2012 (UTC)


 * Resurrecting an old comment here as I've resolved the issue for now by moving the content. Even the cited material refers to the interactome more frequently than interactomes in the plural, much in the same way that "the genome" was used in the earlier days of genomics. There will always be multiple interactomes and even multiple interpretations of the same interactome so this article should never refer to the definitive, singular interactome. JHCaufield - talk - 17:37, 11 March 2015 (UTC)
 * Thanks, your edit helps. SeanAhern (talk) 13:33, 12 March 2015 (UTC)

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Proposed merge with Hypothome
Term not used by any source other than the authors of the article; at most, it should be mentioned as a suggested term at interactome. הסרפד (call me Hasirpad) 15:43, 24 May 2019 (UTC)
 * Agreed, ✅ done! Amkilpatrick (talk) 16:08, 24 May 2019 (UTC)