Talk:Lamotrigine/Archive 2

Bad Pharma
The book Bad Pharma notes that 63% of the trials of this drug have not been published. When dealing with medications, should we consult www.alltrials.net ? People do rely on the information provided by Wiki and if we are passing on bad data, people may be harmed. I know that this would be a huge amount of work but I am prepared to cover as many as possible. I've added patents & papers to over 800 pages (from several IP addresses, but you can spot my standard 'added patent' format. If Wiki supports alltrials, we will be providing information for both doctors and patients. To do this properly we need to get alltrials and specifically Dr. Ben Goldacre to find a feedback mechanism. In addition, checking references with retraction watch will ensure that we give only the best, unbiased references to users. I feel strongly about this because Lamotragine almost killed me because of an unreported side-effect. Maybe the side-effect WOULD be known if the trials were ALL published. — Preceding unsigned comment added by 81.99.74.135 (talk) 22:28, 1 January 2017 (UTC)
 * Patents are not reliable sources in WP, so you have added a bunch of bad referencing that is probably WP:OR to boot - you need some secondary source that says patent X is relevant to drug Y. See WP:SPS which specifically mentions patents.  I hope you will undo all those edits.
 * about alltrials... raw clinical trial data is also not useful in WP; we rely on secondary sources for health content per WP:MEDRS.
 * if you care to say, what was the side effect? we can see if it is reported in a review or the label or not, and if we find it well sourced we can add it.  Jytdog (talk) 06:55, 2 January 2017 (UTC)

Adding to Section Trade Names?
The article might include names of manufacturers now that the formulation is available in a generic form. India's Unichem Laboratories LTD received FDA approval for use in the USA in October of 2011. References: http://unichemlabs.com/wp-content/uploads/2016/08/October_72011.pdf https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=090170 or http://web.archive.org/web/20170628195135/https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=090170#collapseApproval MichelleInSanMarcos (talk) 04:02, 8 March 2018 (UTC)

Use in PTSD
While I have great respect for the work done by Cochrane, I have seen far too many patients improve with PTSD symptoms especially if they have co-occurring bipolar disorder. The avoidance doesn't usually improve, but the irritability, impulsivity, and anger/hyper-arousal usually improve. I'm unaware of any RCTs or much work in general done with this, but a number of colleagues have noticed the same. — Preceding unsigned comment added by 132.239.142.131 (talk) 23:56, 13 January 2021 (UTC)