Talk:Laryngeal papillomatosis

Wiki Education Foundation-supported course assignment
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Allisonchen4.

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Wiki Education Foundation-supported course assignment
This article was the subject of a Wiki Education Foundation-supported course assignment, between 11 September 2017 and 11 December 2017. Further details are available on the course page. Student editor(s): Jlmdouce, Axe30, Sara with no h, Jennamackay. Peer reviewers: Lisakuil, Mil.sch, ABBslp.

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Article categorization
This article was initially categorized based on scheme outlined at WP:DERM:CAT. kilbad (talk) 17:12, 20 May 2009 (UTC)

External links modified
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External links modified
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Identifying areas of improvement
I have identified a number of aspects of improve, including: I personally plan to address the following parts of the article: Potential bibliography to follow. Jlmdouce (talk) 01:09, 28 September 2017 (UTC)
 * Better lead section
 * Photo needed
 * Citations are needed more consistently in all sections
 * Better in-text hyperlinks for medical terms/procedures
 * More information on voice therapy
 * Consider renaming "treatment" section to "management" because there is no cure
 * Consider adding an outcomes section
 * Treatment section needs major revision of medical procedures
 * Consider adding an epidemiology section
 * Address the relationship between laryngeal papillomatosis and recurrent respiratory papillomatosis
 * Contribute to improvement of lead section
 * Add an epidemiology section
 * Edit and add to the diagnosis section as needed
 * Thanks for your notes. The lead should be the last thing updated -- all it does, is summarize sourced content in the body of the article. See WP:LEAD.  In general please see WP:MEDMOS, WP:MEDRS, and WP:MEDHOW.  Jytdog (talk) 02:14, 28 September 2017 (UTC)
 * This article needs a lot of work - i just cleaned out all the bad refs. Jytdog (talk) 03:45, 28 September 2017 (UTC)
 * Thanks for the heads up regarding the lead Jlmdouce (talk) 19:47, 28 September 2017 (UTC)

Hello fellow Wikipedians! I also tried to identify additional elements to improve/modify/explore: For now, I personally plan to address the following parts of the article: --Axe30 (talk) 05:06, 30 September 2017 (UTC)
 * Talk about the evolution/recurrence of the condition
 * Elaborate the signs and symptoms section (Do they appear instantly after infection or do they manifest later? Are they additional/secondary symptoms? Add information about The Derkay staging system. Add information about the relationship between gastroesophageal reflus disease and recurrent respiratory papillomatosis)
 * Consider adding the following sections:
 * 1) Pathology (Investigate the research findings of the molecular mechanism of the disease.)
 * 2) Research
 * 3) Economical impact (The economic burden associated with the frequent surgical procedures was mentioned, it could be interesting to investigate further on the matter.)
 * Minor edits
 * 1) Add synonyms in the grey box.
 * 2) Be consistent with the terminology. For example: use the term "Vocal folds" across articles and avoid using "Vocal cords"
 * Contribute to improvement of signs and symptoms section
 * Add a prognosis section
 * Search for photos that can be used on Wikipedia
 * Search for new reliable sources and citations
 * Read WP:MEDMOS for sections, and WP:MEDHOW for general guidance, and WP:MEDRS about sourcing. Thanks. Jytdog (talk) 04:09, 1 October 2017 (UTC)

Running bibliography
Here is a running list of sources that may be helpful in editing this article:

Colton, R. H., Casper, J. K., & Leonard, R. (2011). Understanding voice problems: a physiological perspective for diagnosis and treatment. Philadelphia: Wolters Kluwer Heath/Lippincott Williams & Wilkins. ISBN-13 9781609138745. pp. 171-172. El-Naggar, A. K., Chan, J. K. C., Grandis, J. R., Takata, T., & Slootweg, P. J. (2017). WHO Classification of Head and Neck Tumours. Lyon: Interventional Agency for Research on Cancer. ISBN-13 9789283224389, pp. 78, 93-95. Fletcher, C. D. M. (2013). Diagnostic histopathology of tumors. Philadelphia, PA: Saunders/Elsevier. ISBN-13 9781455737543, Ch. 4, Table 4B-2 (e-book, no page numbers). Fortes, Helena Ribeiro; Ranke, Felipe Mussi von; Escuissato, Dante Luiz; Neto, Cesar Augusto Araujo; Zanetti, Gláucia; Hochhegger, Bruno; Souza, Carolina Althoff; Marchiori, Edson. "Recurrent respiratory papillomatosis: A state-of-the-art review". Respiratory Medicine. 126: 116–121. doi:10.1016/j.rmed.2017.03.030. Grimes, J., Fagerberg, K., & Smith, L. (2014). Sexually transmitted disease: An encyclopedia of diseases, prevention, treatment, and issues. Santa Barbara, California : Greenwood. IBSN-13 9781440801341, pp. 401-407. Remacle, M., & Eckel, H. E. (2010). Surgery of larynx and trachea. Berlin: Springer. e-ISBN 978-3-540-79136-2, Chapters 6 and 7 Jlmdouce (talk) 19:47, 28 September 2017 (UTC)
 * Etiology, signs and symptoms, pathophysiology
 * Synonyms, ICD-O codes, epidemiology, etiology, clinical features, prognosis and predictive factors
 * Synonyms, normal anatomy, clinical features
 * Etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, pathology
 * U.S. epidemiology, viral etiology
 * Management in children and adults
 * Don't forget to use the MEDRS sources you can find via the box at the very top of this page - it sends you to pubmed, for reviews published in the last five years. Per WP:MEDDATE we prefer recent high quality sources, so try to ditch the books from 2010 and earlier above. There is no sense in updating with outdated refs.... Jytdog (talk) 20:25, 28 September 2017 (UTC)
 * Thanks. I have made changes to the above list as per your recommendations.Jlmdouce (talk) 01:08, 2 October 2017 (UTC)
 * Here are some additional sources that could be useful:

--Axe30 (talk) 13:00, 30 September 2017 (UTC) Edit--Axe30 (talk) 14:10, 1 October 2017 (UTC)
 * Fakhry & D'Souza (2015)
 * Kupfer, Cadalli Tatar, Barry, Allen & Merati (2016)
 * San Giorgi, Helder, Lindeman, de Bock, & Dikkers (2016)
 * Taliercio et al. (2015)
 * Venkatesan, Pine & Underbrink (2012)
 * Would you all please use complete citations. Please include pmid for journals and isbn for books, and page numbers for books.  See WP:MEDHOW. Jytdog (talk) 04:06, 1 October 2017 (UTC)
 * Yes absolutely! Thank you.--Axe30 (talk) 14:10, 1 October 2017 (UTC)

Suggestions for improvement
After looking over this page I have come up with some suggestions for the improvement of this article:

symptoms)
 * Add more to the Signs and Symptoms section (e.g. onset and progression of symptoms, elaborate on what is happening physically to produce these signs or
 * Move information about prevention to its own section "Prevention" rather than keeping it within "Transmission"
 * Add an Outcomes or Prognosis section
 * Add an Epidemiology section
 * Add sub-headings within the Treatment section (include Speech Therapy as its own sub-heading with more information)
 * Medical citations are needed throughout the article
 * Add a photo to the page

I personally plan on working on the following:


 * Adding to the Signs and Symptoms section
 * Adding sub-headings to Treatment section and elaborating on speech therapy
 * Separating the Prevention and Transmission (adding Prevention section)

-Jennamackay (talk) 03:58, 1 October 2017 (UTC)
 * Do not add anything like "why is it important to seek a doctor if these signs or symptoms are present/ if you believe you may have laryngeal papillomatosis." Wikipedia articles do not provide medical advice.  Please read WP:MEDMOS and while you are at it WP:MEDHOW. Thanks. Jytdog (talk) 04:07, 1 October 2017 (UTC)

With regards to the Treatment section, in addition to your suggestions, I think the section must be reworked to reflect current best practice recommendations, and citations must be added. In particular, I plan to add to this section by elaborating on the surgical removal of the papillomas, as well as possible surgical complications (respiratory tract burns, laryngeal scarring, and stenosis), some information on whether adjuvant treatments would be necessary, and when. Sara with no h (talk) 18:46, 3 October 2017 (UTC)

I also agree that an epidemiology section should be included, covering information such as distribution (by age and by gender) and incidence. I will take on the responsibility of adding an epidemiology section.

Sources which I plan to include when updating the treatment and epidemiology sections of the article:


 * Alfano, Devin M. "Human Papillomavirus Laryngeal Tracheal Papillomatosis". Journal of Pediatric Health Care. 28 (5): 451–455. doi:10.1016/j.pedhc.2014.04.003.
 * Avelino, Melissa Ameloti Gomes; Zaiden, Tallyta Campos Domingues Teixeira; Gomes, Raquel Oliveira (September 2013). "Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis". Brazilian Journal of Otorhinolaryngology. 79 (5): 636–642. ISSN 1808-8686. PMID 24141682. doi:10.5935/1808-8694.20130114.
 * Carifi, Marco; Napolitano, Domenico; Morandi, Morando; Dall'Olio, Danilo (2015). "Recurrent respiratory papillomatosis: current and future perspectives". Therapeutics and Clinical Risk Management. 11: 731–738. ISSN 1176-6336. PMC 4427257 Freely accessible. PMID 25999724. doi:10.2147/TCRM.S81825.
 * Fortes, Helena Ribeiro; Ranke, Felipe Mussi von; Escuissato, Dante Luiz; Neto, Cesar Augusto Araujo; Zanetti, Gláucia; Hochhegger, Bruno; Souza, Carolina Althoff; Marchiori, Edson. "Recurrent respiratory papillomatosis: A state-of-the-art review". Respiratory Medicine. 126: 116–121. doi:10.1016/j.rmed.2017.03.030.

Sara with no h (talk) 15:45, 5 October 2017 (UTC)

Some resources that may be useful
The following is a bibliography containing some resources that may be useful in the development of this article:


 * Avelino, Melissa Ameloti Gomes; Zaiden, Tallyta Campos Domingues Teixeira; Gomes, Raquel Oliveira (September 2013). "Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis". Brazilian Journal of Otorhinolaryngology. 79 (5): 636–642. ISSN 1808-8686. PMID 24141682. doi:10.5935/1808-8694.20130114.
 * Carifi, Marco; Napolitano, Domenico; Morandi, Morando; Dall'Olio, Danilo (2015). "Recurrent respiratory papillomatosis: current and future perspectives". Therapeutics and Clinical Risk Management. 11: 731–738. ISSN 1176-6336. PMC 4427257 Freely accessible. PMID 25999724. doi:10.2147/TCRM.S81825.
 * Derkay, Craig S. (2001-01-01). "Recurrent Respiratory Papillomatosis". The Laryngoscope. 111 (1): 57–69. ISSN 1531-4995. doi:10.1097/00005537-200101000-00011.
 * Nicollas, R.; Giovanni, A.; Triglia, J.-M. (June 2008). "[Dysphonia in children]". Archives De Pediatrie: Organe Officiel De La Societe Francaise De Pediatrie. 15 (6): 1133–1138. ISSN 0929-693X. PMID 18440790. doi:10.1016/j.arcped.2008.03.001.
 * Nowińska, Katarzyna; Ciesielska, Urszula; Podhorska-Okołów, Marzenna; Dzięgiel, Piotr (May 2017). "The role of human papillomavirus in oncogenic transformation and its contribution to the etiology of precancerous lesions and cancer of the larynx: A review". Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University. 26(3): 539–547. ISSN 1899-5276. PMID 28791831.
 * Torrente, Mariela C.; Rodrigo, Juan P.; Haigentz, Missak; Dikkers, Frederik G.; Rinaldo, Alessandra; Takes, Robert P.; Olofsson, Jan; Ferlito, Alfio (April 2011). "Human papillomavirus infections in laryngeal cancer". Head & Neck. 33 (4): 581–586. ISSN 1097-0347. PMID 20848441. doi:10.1002/hed.21421.
 * Wierzbicka, Małgorzata; Józefiak, Agata; Jackowska, Joanna; Szydłowski, Jarosław; Goździcka-Józefiak, Anna (July 2014). "HPV vaccination in head and neck HPV-related pathologies". Otolaryngologia Polska = The Polish Otolaryngology. 68 (4): 157–173. ISSN 2300-8423. PMID 24981297. doi:10.1016/j.otpol.2014.05.004.

-Jennamackay (talk) 04:35, 1 October 2017 (UTC)

Lead Working Draft
Laryngeal papillomatosis, also known as recurrent respiratory papillomatosis, is a rare medical condition caused by a human papillomavirus (HPV) infection of the throat. Laryngeal papillomatosis is caused by HPV types 6 and 11, in which benign tumors or papillomas form on the larynx or other areas of the respiratory tract. If left untreated, these tumors/papillomas can obstruct the airway over time and be potentially fatal. Treatment for laryngeal papillomatosis currently aims to remove the papillomas and limit their recurrence. However, due to the recurrent nature of the virus, repeated treatments usually are needed. Laryngeal papillomatosis is currently primarily treated surgically, though supplemental nonsurgical and/or medical treatments may be considered for some patients. The course of laryngeal papillomatosis is highly variable; while some patients do experience recovery, the condition is usually persistent.

(Sources still need to be added; I also welcome any changes that anyone feels should be made. Thanks!!) Sara with no h (talk) 16:45, 18 November 2017 (UTC)


 * The lead should summarize the body and use the same refs used there and be in the same order as the body. Please never write "current" anywhere in WP.  Please never use the word "patient". Jytdog (talk) 18:45, 18 November 2017 (UTC)
 * I have edited the lead on the main space to reflect these comments. Jlmdouce (talk) 22:17, 18 November 2017 (UTC)

Old refs
There are refs here that fail WP:MEDDATE. While you all are updating this, would you please get rid of those and update the content they are supporting based on recent refs? There should be no refs older than 5 years or so and some are from the 2000s. Jytdog (talk) 18:44, 18 November 2017 (UTC)

It was hard
I was diagnosed by a great dr at children’s in Seattle after being transported when my dr told mom I was faking it in 1977. Had 41 surgeries over 10 years. Please msg me if you need help! I went from talking hoarse to being in a bubble until Seattle diagnosed me. Have proof of all of this. Let me know if you have questions. It is still rare but I am now 46 with no issues other than a voice that my coworkers say I need a cough drop for. People in school called me Kermit the frog. Hard yea, but I am alive thankful to children’s in Seattle and dr Chan- no one knew what this was 40 years ago Michellepoundstone (talk) 04:03, 3 November 2021 (UTC)