Talk:Lassa mammarenavirus

Incorrect taxonomy and nomenclature
The page consistently makes the error of using the species name to refer to the virus. Viral taxonomy is not the same as taxonomy for other organisms, and we do not conventionally use species names or other taxonomic units to refer to the virus itself. As such, the page name should be "Lassa virus", and all references to "Lassa mammarenavirus" should be changed to "Lassa virus", except where a direct reference to the taxonomy is made. See ICTV guidelines for more information.

129.109.98.175 (talk) 19:34, 7 May 2020 (UTC)


 * While the previous poster is correct in their statement on usage of virus names in virological publications. The ICTV references already starts biting it's own tail, because the taxonomic name was now only 2 years afterwards set to Mammarenavirus lassaense. Something most virologist will hardly adapt.
 * I would propose the new taxonomic name should be reflected in the taxonomic hierarchy table, while the article uses the common Lassa virus (LASV) descriptor. 82.207.187.7 (talk) 14:21, 2 August 2023 (UTC)

Interferone
Dear Colleagues:

"One of the mechanisms detects double stranded RNA (dsRNA), which is only synthesized by negative-sense viruses."

Methinks the second part of this sentence should read "which occurs only in the life-cycle of RNA viruses": *Every* RNA replication involves temporary formation of dsRNA (and proceeds via a countersense intermediate). For nidoviruses, some of the proteins involved in suppressing the IFN response have been characterized.

Regards 🧬 — Preceding unsigned comment added by 62.165.205.225 (talk) 12:39, 5 May 2020 (UTC)

Introductory paragraph
There is a serious grammar issue in the article overview which needs to be fixed. Specifically, the following sentence:

> Recent discoveries on the Lassa Virus within the Mano River Region provide evidence will require the expansion the endemicity zone between the two known Lassa endemic regions, indicating that LASV is more widely distributed throughout the Tropical Wooded Savanna ecozone in West Africa.

I am afraid to fix the sentence structure for fear of misrepresenting the information, since I am confused about the intended statement. Hoping someone else can take a look at it.

Lily.r.s (talk) 15:33, 30 April 2015 (UTC)


 * I fixed it. Thanks for pointing it out. JosephSpiral (talk) 13:47, 25 June 2015 (UTC)

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Gain of Function at the University of Washington (Seattle)
https://grantome.com/grant/NIH/F30-AI149928-02?fbclid=IwAR0GpjoUpEzz6NqiAZA2Q8tenZPNlVy0hXFLeD9csgvu-wRtx7fY-tdu7Ko "I will completely characterize the ability of mutations to the Lassa virus entry protein to mediate antibody escape from three human monoclonal antibodies currently undergoing therapeutic development. These complete maps of antibody resistance will determine from which antibody it is most difficult for the virus to escape and help evaluate and refine potential antibody immunotherapies." This grant is currently active. Isn't this the definition of GOF? Charles Juvon (talk) 22:10, 11 June 2021 (UTC)