Talk:Leucine zipper

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 27 August 2019 and 6 December 2019. Further details are available on the course page. Student editor(s): Ry19a.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 02:30, 17 January 2022 (UTC)

Leucine zipper binding to DNA???
Why is the diagram being used showing a leucine zipper motif binding to DNA? Leucine zipper motifs are known protein:protein interaction domains, not DNA binding domains. The article itself even says so. EganioTalk 04:57, 4 February 2008 (UTC)


 * You sure? I'm pretty sure the Glick dictionary I used for "leucine scissors" said it was DNA-binding motif too. Additionally the article does say:

"These proteins [-Leucine zipper regulatory proteins-] interact with the DNA as dimers (homo- or hetero-) and are also called basic zipper proteins (bZips)."


 * which to me says leucine zipper molecules interact with DNA. You'll note the picture doesn't have the leucine-containing zipper domain interacting with the DNA. Rather the post-zipper "arms" or "jaws" of teh scissors do.--ZayZayEM (talk) 12:45, 4 February 2008 (UTC)


 * OK, now I see what the diagram is representing...I was looking at it incorrectly. Sorry about that. EganioTalk 04:54, 5 February 2008 (UTC)