Talk:Lignin-modifying enzyme

Untitled
Ligninase was the original name and term for e.g. lignin peroxidase for over 20 years ago. Since then, vast amount of data, biochemical, protein structural and genome sequence data, have piles up and crystallised our knowledege on the ligin degrading enzymes. First of all, there is an array of fungal extracellular oxidoreductases, not only lignin peroxidae or ligninase, that are catalysing lignin breakdown. These are manganese peroxidases, versatile peroxidases, hybrid peroxidases, and also laccases. Secondly, none of the enzymes, in contrast to the enzymes breaking down cellulose and hemicellulose, are hydrolytic. The lignin modifying enzymes (LMEs) are all metalloenzymes and oxidative (electron withdrawing) in action. Therefore, the term "ligninase" should be avoided and instead, the term "lignin-modifying enzyme (LME)" should be used.

Many laccases modify lignin, and any attempt to exclude them from this category because they're not strictly a fungal enzyme, or because they are not specific to lignin, shows a very unscientific bias on the authors part. —Preceding unsigned comment added by 98.235.177.20 (talk) 02:48, 6 May 2010 (UTC)

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