Talk:Linear epitope

From the 2nd paragraph of the intro: "The linear sequence of amino acids that compose a protein is called its primary structure, which does not exist in nature". I'm pretty sure what the editor meant to write was that 'the primary structure [of a fully-formed, native protein] is not presented to antibodies as such...'. I'm not sure if that's what they meant, but either way, two objections: 1) Unless I'm mistaken, there are instances (in general, for normal protein interactions) were the primary structure (at least parts of it) DO exist in nature, meaning that uninterrupted stretches of primary sequence are part of the exposed outer architecture of a protein. 2) At the very least, can we rephrase the "does not exist in nature" to be less absolute, or at least be less suggestive to mean that the primary structure is some imaginary thing? Maybe I'm being too literal, but certainly the primary structure exists as proteins form, before they are folded, and even after: even if its a tangled knot, one does not say the string itself doesn't exist, right?23.24.214.46 (talk) 00:48, 21 November 2017 (UTC)

Still no one will address this, it's an affront to logic. I'm rewording "primary structure, which does not exist in nature" to "...which typically does not present as simple line of sequential proteins, much like a knot, rather than a straight string".23.24.214.46 (talk) 18:52, 30 November 2017 (UTC)