Talk:List of human cell types/Archive 1

Atoms
Is it true that the 98% of the atoms constituting human cells get replaced every year? How is this figure determined? Is it only from some basic metabolic measurements? Can "replacement" exactly be said to be going on, particularly in the light of Penroses' arguments in "The Emperor's New Mind" (if an atom is "replaced" by another of the same kind, then in a strong sense, nothing would have happened whatsoever). comments requested. Many thanks --Amit —Preceding unsigned comment added by 125.21.164.251 (talk) 06:46, 3 September 2007 (UTC)

Thanks for the List!
Wow! This is so nice. Thanks to who ever made this list. Eperotao (talk) 23:46, 29 January 2008 (UTC)

Neurons
One can look at number of different types of neurons in NeuroLex... My very best wishes (talk) 23:50, 28 June 2012 (UTC)

human cells are basic building blocks of all things. The human body is composed of trillions of cells. They provide stucture for the body. tkae in nutrients into enrgy and carry out specilized. the parts of a cell * intermadiate filment * Ridosomes * Rough endopasmic reticulum * nucleus * nuleolus * chromath * golgi appartus * golgi veside *

Diffrent Cell types
how many different cell types are in a human?

There are about 210 (IIRC) different kinds of cells, depending on how strictly you separate similar cells. The article states there are "300 different cell types in the human body. " However, this is under the heading: "Exocrine secretory epithelial cells." This line should be moved above if it applies to all of the human cell types, not just a subset. — Preceding unsigned comment added by Bellteda (talk • contribs) 22:59, 23 May 2013 (UTC)

Dublicates(cells that occurs in more then one of the sub listings)
There are a couple of cells for example Endothelial cells, which occurs under Barrier cells and Extracellular matrix cells. Does it make sense to have the same cells more then one time? if so shoulden't there me more dublicates then there currently is? Claes Lindhardt (talk) 21:50, 2 December 2022 (UTC)

Logic behind Blood and immune system cells
I find it difficult to follow how sometimes the precursers to cells are listed with the cells like: Neutrophil granulocyte and precursors (myeloblast, promyelocyte, myelocyte, metamyelocyte) and then sometimes the precursors to cells are listed as cells in thier own right: Hematopoietic stem cells. It feels like the list on Blood and immune system cells moves very fluently between diffrent levels of abstraction. Is there a particular reason for this? or would it make sense to change it to a more regit listing strategy? Claes Lindhardt (talk) 18:13, 23 November 2022 (UTC)


 * Would it make sense to try and find or make a defintion of how unique a cell have to be to be a cell type on its own? Maybe something like: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175476/ (PMCID: PMC6175476, PMID: 29644800) | https://www.sciencedirect.com/topics/medicine-and-dentistry/cell-type | https://www.eurostemcell.org/cell-identity-and-reprogramming | could be an inspiration? and prehaps especially: https://www.frontiersin.org/articles/10.3389/fpls.2022.868565/full Jeff J. Doyle REVIEW article
 * Front. Plant Sci., 22 August 2022
 * Sec. Plant Cell Biology
 * https://doi.org/10.3389/fpls.2022.868565
 * Cell types as species: Exploring a metaphor Claes Lindhardt (talk) 22:01, 2 December 2022 (UTC)

Should we compare this list to NIHs?
NIH made a list/database of cells: https://meshb.nlm.nih.gov/record/ui?ui=D003239 would it make sense to compare this items in this article to this list? Claes Lindhardt (talk) 20:40, 18 January 2023 (UTC)

Linking cells without article
I've wanted for a long time to see the list of all 210 human cell types and finally found it. I went through the list and added wiki-links where possible, for instance, I changed "Lacrimal gland cell" to "Lacrimal gland cell". My reasoning was that it was more useful to provide a link to a relevant article than show a red-link.

However in doing so, I have also taken away the red-link which shows that we still need an article on the specific cell-type in addition to the article on the gland or organ which contains the cell, and this is now bothering me. Which do you think is more important for this list, showing the articles not yet created, or providing a link to the closest alernative? Would another alternative be: Lacrimal gland -- Lacrimal gland cell ? or Lacrimal gland cell ?

Your comments are appreciated! Franamax (talk) 04:43, 28 March 2008 (UTC


 * Thank you for your contributions! I don't think there need to be two separate articles for the structure and the cells contructing it. Therefore, as I did in Lacrimal gland cell, for example, the cell type may be linked to a Microanatomy or Histology-section in the organ article. Mikael Häggström (talk) 06:46, 29 March 2008 (UTC)


 * That's a problem. This article should be linked to articles about different cell types, not to different tissues. We have articles about many specific types of cells: Category:Cells, Category:Animal cells with many sub-cats, Category:Human cells, Category:Cells by function, etc. (Pericytes, Alpha cell, Beta cell, Acanthocyte, ...). However, many of these types are not mentioned/linked in this page. Articles on other cell types are missing, and I found only one internet resource where cell type descriptions can be found, ,. Biophys (talk) 22:42, 14 July 2010 (UTC)
 * I tried inserting all the cells in this list into a graphic How to build a human poster11.pdf, is there a way to present it nicely on the site once I finish connecting all the cells to where they come from? and where thier function in the body is? Claes Lindhardt (talk) 13:41, 12 January 2023 (UTC)
 * If one click all the way into the PDF, one have decent zoom abilities. But it would be nice if there was a way to zoom in without leaving the article that one is reading? Claes Lindhardt (talk) 13:46, 12 January 2023 (UTC)
 * I made a newer version, Please just tell me which cells belong where or which one is placed wrong then I will update it Family Tree Of Human Cells.pdf Family Tree Of Human Cells.png Claes Lindhardt (talk) 19:46, 19 January 2023 (UTC)
 * A great thanks to Cinthia Castro, who send me some additional neatly formatted data which allowed med to update the family tree once more HumanCellFamTree16032023.pdf We still got some way to go, but hopefully eventually this can serve as a kind of blueprint for everyone who wants to work with stemcells on medical or medical device basis. Kind of like Roche Biochemical Pathways does for biochemistry already Claes Lindhardt (talk) 09:34, 16 March 2023 (UTC)

— Preceding unsigned comment added by 82.12.197.64 (talk) 16:06, 11 December 2012 (UTC)

Reformatting to sortable lists
I started reformatting some of the sublists to sortable lists. With the hope that

a) This can help to standardise the information about all cells

b) it will clarify where information about cells are missing, and make it easier for new contributers to jump on in on the effort.

c) it makes an adaptable overview for the reader of this article Claes Lindhardt (talk) 09:17, 16 March 2023 (UTC)


 * Now I converted all the listed cells into the sortable table format, in this way one could also easily make a sub page with one long list of all of them, where the reader could quicly sort out the sub-group that he finds most relevant. Is there any way to make automatic enumaration on the sortable wiki tables? Claes Lindhardt (talk) 20:18, 26 March 2023 (UTC)

Complexity of a list of cell types
Hello all, and specially.

Thank you so much for your work on this entry! It sorely needed. The task of classifying cell types is very, very hard, and achieving a comprehensive and yet not-too-detailed list is challenging.

Classifying cell types in the context of Wikidata is the subject of my PhD. I recommend this article for grasping a bit the opinions around it: https://www.cell.com/cell-systems/pdf/S2405-4712(17)30091-1.pdf. I still have 1.5 year to go, so I hope to have something more concrete in the future.

As per your questions, I don't see a problem with duplicates, cell types might fit in many different categories.

Comparing the list to NIHs MeSH terms is a good start. If you are interested in the subject, take a look at the Cell Ontology (https://cell-ontology.github.io/) too. It is probably the most comprehensive resource so far (e.g. see https://www.nature.com/articles/s41556-021-00787-7).

Anyways, thank you for the contributions, I encourage you to keep improving it. TiagoLubiana (talk) 07:53, 26 February 2023 (UTC)


 * Dear Tiago,
 * I highly appriciate the feedback, I cannot wait to see what comes from your PhD. Please do send updates.
 * I am reading the articles that you have linked, and will need some more time before I can act on them concretly. But I will keep them in the back of my head as I go forward. Claes Lindhardt (talk) 09:15, 16 March 2023 (UTC)
 * Der Tiago, do you know if there is a youtube 'how to' video which explains how to use the OLS ontology search website(https://www.ebi.ac.uk/ols/ontologies/cl)? Claes Lindhardt (talk) 21:40, 22 March 2023 (UTC)
 * I found https://ontobee.org/ontology/CL?iri=http://purl.obolibrary.org/obo/CL_0000034 very nice, because it shows you in the bottom of the page which ontology uses which classifications one you click on a cell. But I still cannot seem to find anyone who have attempeted making a compelate graphical visual tree of all human cells with thier origin, but maybe I am just using the tools suboptimally? Claes Lindhardt (talk) 21:58, 22 March 2023 (UTC)
 * The HuBMap project also seems very relevant to this article https://expand.iu.edu/browse/sice/cns/courses/hubmap-visible-human-mooc Claes Lindhardt (talk) 22:48, 3 April 2023 (UTC)

Missing knowledge/gaps in understanding
Should maybe also write a bit about what parts of the humans cells that we don't know a lot about and leave gaps, where there is not understanding but we know that there is more to be known HuBMAPS ASCT+B tables and visualisation(which is really the most compleate and easiet to compare thing I have seen so far) only contains somewhat compleate information on Brain, Heart, Spleen, Colon and Kidney. Which is only 5 of the average human approx. 82 Organs(all of which are visualized here in the orange inner ring: ). Claes Lindhardt (talk) 08:53, 26 April 2023 (UTC)

minimum spanning tree
about 10:40 min into the lecturer: 'CODEX Data Acquisition and Analysis', John Hickey makes a minimum spanning tree of the different cell types of different parts of the intestine. Would it make sense to make a such tree for each of the bodies ca. 82 so far known organs, to quickly get an overview of which cells are how present where? and then present those figures first? and end the article on a table list, where people can sort themselfes for features in humans cells? Claes Lindhardt (talk) 14:31, 27 April 2023 (UTC)

Merging all the sortable tables into one
Woulden't it make sense to merge all the sortable tables into 1 grand table? Claes Lindhardt (talk) 09:45, 29 June 2023 (UTC)

Overlap with other article
This article seems to have some overlap in function and purpose with: Category:Human cells ? Claes Lindhardt (talk) 07:36, 7 July 2023 (UTC)

Overview of Cell type DBs?
I saw List of biological databases and wondered it would make sense to make a list of all the emerpical databases with different cell types. Maybe we could use a format something like: Claes Lindhardt (talk) 08:27, 19 July 2023 (UTC)


 * So that it would be easy for a user to compare the list here to something elsewhere quickly, as well as to add other data sources that we can use to compare to and update this one? Claes Lindhardt (talk) 08:28, 19 July 2023 (UTC)

Wikidata Template for Human cells(and maybe also Human Tissue)
Would it make sense to make a template on wikidata for human cells?(I saw a simmilar effort had already been made through: https://lubianat.github.io/quali_phd/), so that we could easily query(https://query.wikidata.org/) all the articles about human cells already on wiki and keep an overview, and assure coherence. Also when we pull from sources like the HubMAP project or https://en.wikipedia.org/wiki/Human_Cell_Atlas. Is there already something like this? that I have overlooked? or does it make sense to make a new one from scratch? Claes Lindhardt (talk) 21:14, 24 August 2023 (UTC)


 * Maybe we could use or give https://www.ebi.ac.uk/ols/ontologies/hcao a look? Claes Lindhardt (talk) 07:33, 26 August 2023 (UTC)