Talk:Lofepramine

Untitled
this is a well-known drug... shouldn't be hard to gather all of the info... --Lieutenant Colonel Frank Slade 03:18, 10 July 2006 (UTC)


 * Only one sentence here, but I removed 'primarily for sleeping and eating disorders' cause I am not too sure about that, think it is less sedating than other tricyclics so would be less likely to be used for sleep disturbance. Poss. use in eating disorders but I do not think 'primarily'. I think its only official indication at least in the UK is depressive disorders so that's what I've changed it to, if anyone has any other info then feel free to edit. Berry

This medication appears to be prescribed occasionally to patients presenting with PTSD because of the anxiety and depressive states normally associated with this illness. There are no indications or research on it's use for PTSD. It would be interesting to note if this medication did reduce and limit the presenting symptoms of this illness. As there appears less scope for side effects compared to other types of similar medication which would be prescribed. [User:Traumadoc/ Bennett]

Structure
It's not a phenethylamine, but contains a phenacyl group (acetophenone derivative), see http://books.google.de/books?id=yXD4QA-Y_Z0C&pg=PA192&lpg=PA192&dq=23047-25-8&source=bl&ots=Ut64R2665F&sig=WSYORZmXYxLCdYgKRO6G5akYY1k&hl=de&ei=hx-STKLwJ46UOOLeld0H&sa=X&oi=book_result&ct=result&resnum=5&ved=0CCoQ6AEwBDgK#v=onepage&q=23047-25-8&f=false --FK1954 (talk) 13:48, 16 September 2010 (UTC)
 * This will be my job ;-) --benutzer:Roland1952 (talk) 14:10, 16 September 2010 (UTC)
 * Well done, thank you! Gruß --FK1954 (talk) 12:33, 24 September 2010 (UTC)
 * You´re welcome, see you. Regards --benutzer:Roland1952 (talk) 13:17, 24 September 2010 (UTC)
 * I guess you'll understand German ;-) : auf Dich ist Verlass, Roland! Gruß und schönes Wochenende! --FK1954 (talk) 19:23, 24 September 2010 (UTC)
 * For anyone coming back to this in the future, the incorrect image was File:Lofepramine.svg, which was corrected as File:Lofepramin.svg. DMacks (talk) 06:41, 4 January 2011 (UTC)

neurotransmitters involved
This article has no indication of what the main mechanism of action is. This is a basic feature of all the other tca articles... 72.229.173.197 (talk) 17:26, 23 January 2011 (UTC)

Moved from article
I have moved the following content here because it lacks context/explanation. If anyone wants to use it to improve the article, here it is. -- Ed (Edgar181) 19:32, 13 February 2017 (UTC)
 * Lofepramine synthesis.svg

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Molecular diagram
The 3d model of lofepramine is missing a chlorine group on its benzoyl group’s para position carbon. 2A01:4C8:C04:75F8:316B:DBF5:89D:B0B2 (talk) 23:20, 26 November 2021 (UTC)