Talk:Macrocycle

Sources needed
Sources are needed for the applications and biological sections. Xandrox (talk) 00:06, 23 January 2012 (UTC)

Origin of the word macrocycle
If this article grows to a suitable length, a section on the history of the concept and the origin of the term macrocycle might be appropriate, so here are some references. The Oxford English Dictionary says macrocyclic came first and macrocycle followed. The first record of the word macrocyclic was in 1926, referring to the shape of a fungus. Wallace Carothers's article [http://dx.doi.org/10.1021/ja01339a054 ''J. Am. Chem. Soc. 1933 55'', 5023-5031] is the first instance in a chemistry context. The OED traces macrocycle to a line in Nature 1956 177, (4498), 69-70, which is an announcement about an upcoming conference, but the earliest mention I found was a paper from four years before the note in Nature, [http://dx.doi.org/10.1039/JR9520005008 J. A. Elvidge, R. P. Linstead, "976. Conjugated macrocycles. Part XXIV. A new type of cross-conjugated macrocycle, related to the azaporphins", ''J. Chem. Soc.'' 1952, 5008-5012].

--Ben (talk) 10:01, 28 April 2016 (UTC)

Clarification
Hello - is it possible to clarify: are nutritional macromolecules such as protein, carbohydrates or fats cyclic macromolecules? Thank you. KStar777 (talk) 15:06, 15 June 2017 (UTC)
 * In general, proteins, carbohydrates, and fats are not cyclic (though there are a few exceptions). -- Ed (Edgar181) 15:16, 15 June 2017 (UTC)

That double bond is pretty long.
Why? Alfa-ketosav (talk) 08:17, 27 September 2018 (UTC)