Talk:Medium-chain acyl-coenzyme A dehydrogenase deficiency

Moved from the original page
The present page is:
 * written from the perspective of a paediatric pathologist, largely intended for parents and other family members who have experience of Sudden Unexpected Death in Infancy. I hope the biochemistry will be checked and refined by biochemists

I know absolutely nothing about this, but I've moved it from MCAD, which now redirects here, as I don't believe pages should be titled by acronyms (with AIDS as one possible exception). JFW | T@lk  14:49, 29 Jul 2004 (UTC)

MCAD vs MCADD typography
I take the view that MCAD should always be in italics to avoid confusion with MCADD the condition. This would avoid some visual confusion in the article, yet would alter the existing typography the least.

Eyreland (talk)

My experience
I know a baby with MCADD. She was diagnosed via a routine blood test shortly after she was born. That possibility isn't mentioned in this article, and that's the only change I can think of. Any time she's not keeping food down, she needs to be taken to an ER and put on a glucose IV - just saline and sugar. No lipids, which are fats which contribute to the problem, and apparently commonly used in IVs - it was the ER doctor's main question the first time this baby went in, answered clearly in the letter from the baby's metabolic specialist to the ER doctors. First time was two nights in the ER, second time was one night. Just kept on the IV until she could keep down food reliably (formula / breast milk). So, while the serious need to get to an ER is certainly exciting, treatment was very straightforward. She's about three months old, and this has happened twice. — Darxus (talk) 18:12, 24 February 2012 (UTC)

Oh, the other issue, which is basically mentioned in the article, is that she needs to be fed very regularly. Every 3 hours for the first couple months.—Darxus (talk) 18:15, 24 February 2012 (UTC)

I am the father of three MCADD children. Our first child died at 3 years 7 months and the autopsy showed up MCADD. Our subsequent children were diagnosed with MCADD from blood tests after they were born. The above information is correct in so far as an IV drip to maintian blood glucose is important treatment. However, families should be aware that ER staff may well not have heard of MCADD and so a letter written by a specialist advising treatment very much speeds up the action required. This is important as it is imperative that young children with MCADD should not be allowed to be in metabolic shock for any length of time. Parents should know that their young and very young children can absorb sugars directly through the roof of their mouth and so even if they are incapacitated a parent's finger dipped in honey can be placed in the child's mouth and blood glucose levels will be increased. Very young children will also suckle on the finger and therefore ingest the sugars further helping blood sugar levels. Ian, New Zealand — Preceding unsigned comment added by 202.37.32.2 (talk) 22:37, 28 March 2012 (UTC)

Rewrite
I just finished and copied over from my user page, a fairly major rewrite of the article. Reliable, secondary sources, and hopefully fairly understandable. Canada Hky (talk) 23:40, 9 June 2012 (UTC)

ICD-10 Code
I have added the ICD-10 Code as per the reference but the connecting link does not seem to work. I cannot detect the problem. I would be glad if somebody can contribute.  D ip ta ns hu Talk 04:28, 27 January 2013 (UTC)