Talk:Mesenchymal stem cell

"Medicinal Signaling Cells"
As a biologist, I have never heard this term used to describe MSCs before- I am skeptical that this term is widespread and think it should be removed. — Preceding unsigned comment added by 128.151.150.25 (talk) 20:21, 31 August 2023 (UTC)


 * Caplan used the term prolifically in the last 15-20 years. 98.146.165.112 (talk) 22:55, 9 July 2024 (UTC)

Untitled
I'll add more on the things mentioned below later but right now Cquan has repeatedly deleted information added to this page - our lab www.case.edu/med/dotel is looking at targeting mesenchymal stem cells, is this promotional or informational? Also our lab generally uses percoll before plating cells Tom Kean 23:48, 23 April 2008 (UTC)

Ideas for things to be added: Dr Aaron 12:29, 16 November 2006 (UTC)
 * Markers of MSCs (Sca1+Lin-; Stro-1; etc).
 * Notes on uses of MSCs cell-based therapy
 * Normal role of MSCs in vivo
 * Historical background to MSCs (identification, culturing etc.)


 * Heterologous - Homologous - Homogenous ?


 * Homogenous/heterogenous for cells (homologous for DNA) - I fixed the text too. Dr Aaron 06:12, 28 November 2006 (UTC)

Wiki Education Foundation-supported course assignment
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Phoebehunter40.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 03:55, 17 January 2022 (UTC)

Clearer definition
I think it would be incredibly meaningful for the definition of mesenchymal stem cell to be defined in a more clear and concise manner. Currently, it is very ambiguous and in some ways misleading to the reader. Additionally I think it would be useful to write more about the sources of these stem cells. — Preceding unsigned comment added by Phoebehunter40 (talk • contribs) 15:18, 28 June 2017 (UTC)
 * New Talk comments go at the bottom of this page and are signed and dated by clicking on the pen icon at the top left of the edit box. You are apparently a student learning to contribute to Wikipedia. It would be appropriate to suggest an edit here on the Talk page, using your own definition and sources that adhere to WP:MEDRS, i.e., reviews and authoritative expert summaries. --Zefr (talk) 15:29, 28 June 2017 (UTC)

Stem vs stromal cell
Hi everyone, I would like to suggest that we change the title of this article to "mesenchymal stromal cell". There has been an ongoing debate about the true "stemness" of MSCs and the ISCT (International Society for Cell & Gene Therapy (ISCT) has published the recommendation to use "mesenchymal stromal cells" for the bulk population (https://www.isct-cytotherapy.org/article/S1465-3249(19)30841-2/fulltext). This article confers the impression that mesenchymal stem cell and mesenchymal stromal cell can be used synonymously and I do not think that this is correct/current consensus. What do you think? Explorative Alpaca (talk) 09:14, 26 April 2022 (UTC)

Reference 21 is now a retracted article
Reference 21 at the time of writting was "Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, et al. (July 2002). "Pluripotency of mesenchymal stem cells derived from adult marrow". Nature. 418 (6893): 41–9. Bibcode:2002Natur.418...41J. doi:10.1038/nature00870. PMID 12077603. S2CID 47162269.".

See https://www.nature.com/articles/s41586-024-07653-0 Egon Willighagen (talk) 15:31, 17 June 2024 (UTC)

CD34+ hematopoietic is absolutely found in bone marrow.
Hematopoietic CD34+ is more prevalently found in bone marrow than any other tissue. This article is very skewed toward regenerative potential of adipose, which is laughable as it id the landfill of the body storing refuse. 98.146.165.112 (talk) 23:01, 9 July 2024 (UTC)