Talk:Milk-alkali syndrome/Archive 1

Pathophysiology
I see that an anonymous editor has given a much more detailed and technical description of the pathophysiology. I have tried to integrate the resulting two paragraphs, but as I am not a physiologist, my efforts at copy-editing need to be checked. --Slashme (talk) 11:15, 11 June 2008 (UTC)

I don't think hypercalcaemia predisposes to fractures, just bone pain. Though I'm subject to correction on this. Mjcdowling (talk) 16:18, 28 April 2012 (UTC)

Clinical
Someone has stated that milk-alkali is a cause of secondary hyperparathyroidism. This doesn't seem right, as secondary hyperparathyroidism is by definition an increase in PTH in response to hypocalcemia, whereas milk-alkali syndrome causes a decrease in PTH because of (exogenous) hypercalcemia. 142.21.15.116 (talk) 19:47, 25 June 2014 (UTC)

Goals to Improve this Article
The mechanism and pathophysiology of milk-alkali syndrome should be expanded on even though they are still relatively unclear. Here's a more recent review article that we can use: J.Chin, Future UCSF Pharm.D. (talk) 22:12, 26 July 2021 (UTC)

Here's another review article: J.Chin, Future UCSF Pharm.D. (talk) 22:34, 26 July 2021 (UTC)

The organization of the article can be improved by adding a section on Prevention. - J.Jones UCSF (talk) 04:21, 27 July 2021 (UTC)

Overall grammar and sentence structure of the article could be improved. For example, remove "In medicine, ..." at start of article, specify the word "it" in paragraph two, and limit use of semicolons. - J.Jones UCSF (talk) 04:21, 27 July 2021 (UTC)

Add more references, notably to sections that have only one reference. Here is a review article pertaining to milk-alkali syndrome. - J.Jones UCSF (talk) 04:21, 27 July 2021 (UTC)

The mechanism and treatment section is lacking and should be updated. Diagnosis and signs + symptoms could be combined into one section for an easier read. Nkhair73 (talk) 20:20, 27 July 2021 (UTC)

Change order of sections to : 1. History 2. Epidemiology 3. Causes 4. Mechanism 5. Signs and Symptoms 6. Diagnosis 7. Treatment 8. Outcomes 9. Prevention Nkhair73 (talk) 20:32, 27 July 2021 (UTC)

Peer review

 * Do the group's edits substantially improve the article as outlined in the Wikipedia peer review "guiding framework"?
 * The article contains a brief yet concise lead section that is easy to understand. Its structure is clear and organized, including a table of content that quickly provides an overview of the article. Coverage is balanced for each of the sections, but additional content could be included within the "Outcomes" section or it can be included as a sub-header instead. LikiJNg (talk) 21:41, 2 August 2021 (UTC)
 * The group has added appropriate sections to add relevant information and expand the existing article. The new sections added are also appropriate following the manual of style for medicine-related articles. LCapistrano (talk) 21:35, 2 August 2021 (UTC)
 * The article has an informative and relevant lead-in with a clear article structure and thorough treatment of each topic. The epidemiology section could be improved by separating out historical information (e.g. changing treatments for heartburn and peptic ulcers) from modern statistical information that might be more relevant to readers at a glance. Lauren.tweedie (talk) 21:46, 2 August 2021 (UTC)
 * The group contains a good lead section in the beginning that provides a concise overview of the topics describing what it is, signs & symptoms of the condition, treatment, and complications. Overall, each section was significantly expanded upon and the content that was added was relevant to each section along with the new secondary sources that cited. One suggestion I have is linking the following terms to wiki for readers who may not be as familiar with these medical/scientific terms: myocardial infarction, hydroxylation, hyalinization. LHuang2023 (talk) 16:41, 3 August 2021 (UTC)
 * Has the group achieved its overall goals for improvement?
 * The group was able to achieve its overall goals for improvement as they fulfilled each of the tasks outlined on the Talk page. The addition of the various sections and rearrangement of sections greatly improved the flow of the article and provided it with much more depth. LikiJNg (talk) 21:26, 2 August 2021 (UTC)
 * The article was substantially improved from its last version prior to this group's edits. Many sections were expanded from 1-2 sentence stubs to have more complete information on each subtopic and the citations used are generally of high quality. The expansion of the info box helps readers understand MAS at a glance. Lauren.tweedie (talk) 21:32, 2 August 2021 (UTC)
 * The group achieved their overall goals improving the structure, content, and sources of the article. Sections were updated with relevant information and the group provided thorough explanations for each sub-topic. LHuang2023 (talk) 16:41, 3 August 2021 (UTC)
 * Does the draft submission reflect a neutral point of view?
 * The majority of the draft submission reflects a neutral point of view. The content in each section is purely informational and associated with the appropriate source. A few word choices can be swapped to avoid definitive language. For example, in the "Diagnosis" section under the subsection "Lab Work" changing "Lab work must be done" to "Lab work is needed." Additionally under the "Prevention" section, being more careful with definitive statements like "...is the single best way" will further help to reflect a more neutral point of view. Although it's cited with sources, it may be the point of view of the authors from the source.LCapistrano (talk) 21:47, 2 August 2021 (UTC)
 * Are the points included verifiable with cited secondary sources that are freely available?
 * Some citations are fairly out of date (one from 1982 and another from 1966) but may still contain relevant information. The citations generally are sourced from high quality peer reviewed journals with varying degrees of free availability - including sources from e.g. Cureus as an open access journal improves reader access to sources but a number of journals have paywalls e.g. Clinical Endocrinology. I don't believe these sources are inappropriate to use in the article but it's worth keeping in mind to use open access citations where available. Lauren.tweedie (talk) 21:16, 2 August 2021 (UTC)
 * Are the edits formatted consistent with Wikipedia's manual of style?
 * The edits formatted are very much consistent with Wikipedia's manual of style. Proper lead section, article titles, headings, sections, tables and content box were included. An image was also included in relation to the topic, which is something that our group should consider including to help improve the visuals of our article. One suggestion is to include more Wikilinks when mentioning medical or scientific terms in order to provide readers with additional resources to help build up context when reading certain sentences.LikiJNg (talk) 21:50, 2 August 2021 (UTC)
 * Do the edits reflect language that supports diversity, equity, and inclusion?
 * The edits reflect language that supports diversity, equity, and inclusion. No phrases that suggest victimhood were used, ex: The group wrote "when people began experiencing adverse effects from..." not "when people were afflicted by" or "suffered from" and they used appropriate, non-derogatory terminology for psychiatric conditions mentioned in the article. Gender neutral terms were used throughout the article incorporating words such as "people". Only suggestion would be to replace "patients" with "people" in the article. LHuang2023 (talk) 21:39, 2 August 2021 (UTC) User:LHuang2023

REFERENCE EDITS: '''Together as a group we: - Consolidated duplicate references for:'''

1. Medarov BI (2009). "Milk-alkali syndrome". Mayo Clin Proc. 84 (3): 261–7. doi:10.1016/S0025-6196(11)61144-0. PMC 2664604. PMID 19252114.

2. Ali, Rimsha; Patel, Chinmay (2021), "Milk-Alkali Syndrome", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 32491432, retrieved 2021-08-04

3. Patel, Ami M.; Goldfarb, Stanley (2010-09-01). "Got Calcium? Welcome to the Calcium-Alkali Syndrome". Journal of the American Society of Nephrology. 21 (9): 1440–1443.

- Reformatted the references (removed month and date) for:

1. Orwoll, Eric S. (1982-08-01). "The Milk-Alkali Syndrome: Current Concepts". Annals of Internal Medicine. 97 (2): 242. doi:10.7326/0003-4819-97-2-242. ISSN 0003-4819.

2. Texter, E. Clinton; Laureta, H. C. (1966-05-01). "The milk-alkali syndrome". The American Journal of Digestive Diseases. 11 (5): 413–418. doi:10.1007/BF02233637. ISSN 1573-2568.

3. Patel, Ami M.; Goldfarb, Stanley (2010-09-01). "Got Calcium? Welcome to the Calcium-Alkali Syndrome". Journal of the American Society of Nephrology. 21 (9): 1440–1443.

4. Rehan, Mehboob A.; Rashid, Asma; Krell, Kenneth; Gabutti, Cristina; Singh, Reema. "Calcium Alkali Thiazide Syndrome: What We Need to Know". Cureus. 12 (10): e10856. doi:10.7759/cureus.10856. ISSN 2168-8184. PMC 7652029. PMID 33178509.

5. Felsenfeld, Arnold J.; Levine, Barton S. (2006-07-01). "Milk Alkali Syndrome and the Dynamics of Calcium Homeostasis". Clinical Journal of the American Society of Nephrology. 1 (4): 641–654.

6. Abugroun, Ashraf; Tyle, Aneesh; Faizan, Farah; Accavitti, Michael; Ahmed, Chaudhary; Wang, Theodore (2020-03-16). "Hypercalcemia-Induced ST-Segment Elevation Mimicking Acute Myocardial Injury: A Case Report and Review of the Literature". Case Reports in Emergency Medicine. 2020: 1–5. doi:10.1155/2020/4159526. ISSN 2090-648X. PMC 7102466. PMID 32257460.

7. LeGrand, Susan B.; Leskuski, Dona; Zama, Ivan (2008-08-19). "Narrative Review: Furosemide for Hypercalcemia: An Unproven yet Common Practice". Annals of Internal Medicine. 149 (4): 259. doi:10.7326/0003-4819-149-4-200808190-00007. ISSN 0003-4819. J.Chin, Future UCSF Pharm.D. (talk) 22:07, 4 August 2021 (UTC)

Alkaline in milk
Milk 2402:8100:2842:1C51:B2D4:E7CB:A41D:1852 (talk) 10:47, 23 November 2021 (UTC)

Wiki Education Foundation-supported course assignment
This article was the subject of a Wiki Education Foundation-supported course assignment, between 7 June 2021 and 27 August 2021. Further details are available on the course page. Student editor(s): J.Jones UCSF, J.Chin, Future UCSF Pharm.D., Nkhair73, J.Chao, Future UCSF Pharm.D. Peer reviewers: LikiJNg.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 04:11, 17 January 2022 (UTC)