Talk:Neuroacanthocytosis/GA1

GA Review
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Reviewer:  Jimfbleak -  talk to me?  07:00, 26 April 2010 (UTC) Comments soon


 * Images
 * File:US-NIH-NINDS-Logo.svg although federal works are PD, I'm not sure if this applies to logos. Can you clarify please? Actually, I'm not sure why NINDS is singled out to have its logo with a spammy caption, best to remove I think
 * File:Autosomal recessive inheritance.gif claimed as PD, but Genzyme page says © 2003-2010 Genzyme Corporation. All rights reserved
 * File:XlinkRecessive.jpg linked source doesn't show this image, can you fix the link please
 * Jimfbleak--this editor didn't load the image, and was operating on the information given on the commons page.
 * I don't like the left-aligned images that cut across section subheadings, better to right-align
 * the section headings are broken by the image. He thinks this is unappealing.  Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * I have added a tag to the image showing an identifiable face, and I have tagged another image for the border to be removed. Snowman (talk) 10:34, 27 April 2010 (UTC)


 * Regarding the image of person with medication induced dystonia: more details needed. The image needs explaining - he has an IVI and appears to be in a hospital bed with the right (his right) cot side up. What does the image demonstrate? What drug(s) caused this? Is this temporary, permanent, experimentally induced, or a side effect. Is there any confusion with dyskinesia? Where was this image taken? Is the subject of the image a patient? I note that the image description on commons appropriately says that the person has given permission for the image to be shown; nevertheless, I anticipate that permission needed to divulge medical details is entirely different to permission for showing an image. I expect that a separate permission would be needed to reveal his medical details here, so please check your permissions before adding any clinical details. However, going on the sparse information available at this juncture, I think that the image should not appear on the page, since it probably partly illustrates a drug-induced movement disorder and not neuroacanthocytosis. Snowman (talk) 16:26, 27 April 2010 (UTC)
 * Yes this is most probably a drug induced disorder. The person gave written content for the us of their image on Wikipedia in full understanding of what that entailed. Doc James  (talk · contribs · email) 19:38, 4 May 2010 (UTC)


 * References
 * could journal titles be written in full please. Also note that page ranges should be given with ndashes ( – ) not hyphens
 * he means here that you need to fix the references so that the journal titles are written out, not abbreviated. Page ranges should be done with the wiki dash, this way:  ( – ), not with a simple typed dash.  Your references are not consistently cited...Book names and journal names should be italicized.  I'm not sure why there are so many double colons in the citation text, and I thought you had fixed this.  I fixed one of each, but then you needed to do the rest.  Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * The style of referencing seems odd (I compared it with the Down syndrome FA to check that it wasn't a project thing). Books italicised, but not journals (although not consistent, some are italicised), web/print in most cites, lots of double colons. Is there a precedent for this style?


 * Content
 * Anticipation and XK are dabs, Chorea and Pedigrees are redirect pages to dabs. No dead links.
 * dabs=disambiguation pages. Pages that list a lot of possible articles for the direction you want your reader to take, but you need to select the proper article.  Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * Table has text right up to the box, is it possible to put some white space in, like the cladogram here
 * I don't know how to fix this either. Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * Lots of wrong/inconsistent caps, I've fixed some, but there are several others. Parkingsonism surely should be capped?
 * within-article links like those in para 1 aren't good. Change them to proper wikilinks to the articles, and write short stubs based on what you have here for any red links.
 * yes, I agree with this.
 * acanthocytes is off-putting in the opening line, how about a parenthetical gloss to save readers having to follow the redirect here, rather than in para 2?
 * this means an explanation in parenthesis.
 * not sure that favor is a good word for nasty diseases
 * Overlinking, please check eg acanthacytes is linked at least three time including twice in the lead
 * usually, only only one link per article, unless there is a specific reason to link more than once. Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * "Research" is very flimsy, mentioning just one institution, presumably chosen because it's American. See this for other involved bodies
 * Your research section needs expansion of other institutions that are involved in studying these diseases.  Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * "Chorea Acanthocytosis" capped in subheading, not in next line. Why is Chorea capped throughout? It doesn't look like a proper noun
 * consistency of capitalization.
 * Check prose, too many howevers, and plus used instead of and or also
 * Yes, this is an issue, although not as much as it used to be. Auntieruth55 (talk) 19:16, 26 April 2010 (UTC)
 * Why not combine "onset" and "incidence" subsections to avoid having such tiny subsections?
 * Eye of the tiger’s sign seen on an MRI caused by excess iron deposition in the globus pallidus. Viewed on an MRI, this region appears like a tiger's eye, indicating excess iron and suggesting PKAN. (spherical section of the brain) repetitive
 * Family history of McLeod syndrome and family history both listed as diagnostic for McLeod's. How do these differ

More comments on text to follow, but I think the article basically needs a good copy-edit  Jimfbleak -  talk to me?  07:32, 26 April 2010 (UTC)

translations needed
Jimfbleak, I've read some of your comments on this article. This is the student's first wikipedia article, and some of your wiki-cabulary is beyond her ken. I'll help with the copy edit, but could you help us clean up the images and white space(I don't know how to do that either). Auntieruth55 (talk) 19:08, 26 April 2010 (UTC)

Saralo16, I added the stub for Bassen Kornzweig's disease, but you'll need to add a stub for the Huntington's Disease-like etc. Auntieruth55 (talk) 22:23, 26 April 2010 (UTC)

AuntieRuth, thanks for your comments, help and translation, I'll be gentle. I don't know how to fix the whitespace either, and I won't make it a deal-breaker, but it would be good if it could be fixed - I'll ask around. I'll let the alleged US government image go for now, although it would be good to have a link to the actual source image, but I can't see how the Genzyme one can possibly be PD as it's claimed to be, so I think that must go. The NINDS logo is, I think unnecessary and parochial whatever its status, so no loss if that goes either. There's no rush with this.  Jimfbleak -  talk to me?  05:39, 27 April 2010 (UTC)
 * good thinking with the table, I've copy-edited the lead to reduce verbiage. I've also fixed the subheadings again, since incorrect capitalisation (Incidence) had crept back, also replaced & with "and" - former too informal  Jimfbleak -  talk to me?  05:50, 27 April 2010 (UTC)

Comment: I see that each of the diseases has its own wikipage. I think that there should be a better balance with the information in this article and the individual disease pages. Perhaps this page should be more of an overview to avoid a lot of repetition. Snowman (talk) 10:29, 27 April 2010 (UTC)


 * Auntieruth and Jimfbleak, thank you for all of your comments and help! Snowman, I agree with you but this is for a class project so after the grading is done I will move most of the information on the other diseases into their own pages. Thanks. Saralo16 (talk) 15:19, 27 April 2010 (UTC)
 * I think that the current data organisation (with this page lumping details of the separate diseases) across the relevant wiki articles is inconsistent with this page achieving a GA. Snowman (talk) 15:50, 27 April 2010 (UTC)
 * Please clarify what is meant by "class project" and "after the grading is done"? Snowman (talk) 15:52, 27 April 2010 (UTC)
 * This article is going to be graded by my professor and it has a length requirement so when I started working on it months ago and included these sections, I did not realize it was going to be a problem. This is my first wikipedia article so I am learning what and what not to do. The article will most likely be graded by the end of this week, so I will be able to move the information to their own stubs sometime after that. Saralo16 (talk) 16:02, 27 April 2010 (UTC)
 * Regarding data organisation options: the topic could be presented in topic book or more than one article could be presented (separately or assembled). Snowman (talk) 16:32, 27 April 2010 (UTC)


 * I would mention the exact incidence of the diseases rather than saying rare and very rare and so on. The genetics section does not say anything about spontaneous genetic abnormalities, which could contribute a sizeable proportion of affected people for very rare genetic diseases. You might comment on consanguinity. I think that the enzymes could be more directly linked to the illnesses in the introduction. I think that one or two more grand tables to summaries sourced information would be useful. Does your professor know that you are doing your project this way? I guess that he would want to assess your contribution to this collaboration. Snowman (talk) 16:20, 27 April 2010 (UTC)


 * The incidence of the disease is in the onset and incidence sections ... should I put that in the lead paragraph as well? The spontaneous genetic abnormalities are not known since they are so rare. I put what genes they are and what proteins they affect but I'm not sure what else you think I should add. And yes, my professor has seen my article and knows how it is set up. About the dystonia photo, I didn't take it I got if off of wikimedia commons because I have been struggling finding photos to add to my article. I thought that even though it is medically induced, it would give the reader an idea of what dystonia looks like in patients. Do you have any suggestions for other photos I could add? Thanks for all your help! Saralo16 (talk) 20:26, 30 April 2010 (UTC)
 * The image is on the dystonia page, so there is no need to show the image here. I think that the image shows a different problem to the topic of this page, so I think that the image should be removed from this page. Snowman (talk) 11:02, 4 May 2010 (UTC)


 * Spontaneous abnormalities are rare, so spontaneous abnormalities can induce a sizeable proportion of the genetic defects that cause rare diseases. The "X-linked recessive" disease mentioned might be expected to have % of spontaneous abnormalities - one abnormal gene is expressed in males. Spontaneous abnormalities are not mentioned in the article. Snowman (talk) 11:02, 4 May 2010 (UTC)