Talk:Norbert Perrimon

notes from "daughter"
There were recently two IP editors who added amusing notes about Perrimon's dogs, and added a reference for "daughter". Hmm. Let me just say that according to WP:NOR ("no original research"), information has to be published in an independently verifiable source to be included here in Wikipedia, and "no original research" means no information from personal knowledge. Sorry, girl(s)! I have reverted these charming tidbits per Wikipedia policy. --Lquilter (talk) 00:06, 3 December 2013 (UTC)


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list of significant papers

 * An IP editor pasted in an enormous list of Perrimon papers, without wiki formatting, and without selection. (diff)  I reverted (diff) but am including the list below.  The criteria for including the papers is "notable", not all-inclusive; so if the anonymous editor or someone else wants to go through and pick out the most-cited or otherwise most-notable papers from this list, that would be great.

Drosophila unpaired encodes a secreted protein that activates the JAK signaling 	pathway. Genes and Development 12, 3252-3263. The evolutionarily conserved porcupine gene family is involved in the processing of          the Wnt family. Eur J. Biochem. 267, 4300-431     	Development 128, 2905-2913
 * 1) 	Perrimon, N. and Gans, M. (1983) Clonal analysis of the tissue specificity of recessive female sterile mutations of Drosophila melanogaster using a dominant female sterile mutation Fs(1)K1237. Dev. Biol. 100, 365-373.
 * 2) 	Perrimon, N. (1984) Clonal analysis of dominant female sterile, germline- dependent mutations in Drosophila melanogaster. Genetics 108, 927-939.
 * 3) 	White, R. H., Perrimon, N and Gehring, W. J. (1984) Differentiation markers in Drosophila ovary. J. E. E. M. 84, 275-286.
 * 4) 	Perrimon, N., Engstrom, L., and Mahowald, A. P. (1984). The effects of zygotic lethal mutations on female germ-line functions in Drosophila. Dev. Biol. 105, 404-414.
 * 5) 	Perrimon, N., Engstrom, L., and Mahowald, A. P. (1984). Developmental genetics of the 2E-F region of the Drosophila X-chromosome: A region rich in "developmentally important " genes. Genetics 108, 559-572.
 * 6) 	Perrimon, N., Engstrom, L., and Mahowald, A. P. (1985). A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster. Dev. Biol. 110, 480-491.
 * 7) 	Perrimon, N., Engstrom, L., and  Mahowald, A. P.  (1985). Developmental genetics of the 2C-D region of the Drosophila X-chromosome. Genetics 111, 23-41.
 * 8) 	Mortin, M. A., Perrimon, N. and Bonner, J. J (1985) Clonal analysis of two mutations in the large subunit of RNA polymerase II of Drosophila. Mol. Gen. Genet. 199, 421-426.
 * 9) 	Degelmann, A., Hardy, P., Perrimon, N. and Mahowald, A. P. (1986) Developmental analysis of the torso-like phenotype in Drosophila produced by maternal effect locus. Dev. Biol. 115, 479-489.
 * 10) 	Perrimon, N., Mohler, J. D., Engstrom, L and Mahowald, A. P. (1986) X-linked female sterile loci in Drosophila melanogaster. Genetics 113, 695-712.
 * 11) 	Perrimon, N. and Mahowald, A. P. (1986) l(1)hopscotch a larval-pupal lethal with a specific maternal effect on segmentation in Drosophila. Dev. Biol. 118, 28-41.
 * 12) 	Petschek, J., Perrimon, N., and Mahowald, A. P.  (1987). Region specific effects in l(1)giant embryos of Drosophila melanogaster. Dev. Biol. 119, 175-189.
 * 13) 	Perrimon, N. and Mahowald, A. P. (1987) Multiple functions of the segment polarity genes in Drosophila. Dev. Biol. 119, 587-600.
 * 14) 	Mark, G. E., MacIntyre, R. J., Digan, M. E., Ambrosio, L. and Perrimon, N. (1987) Drosophila melanogaster homologs of the raf oncogene. Mol. Cell. Biol. 7, 2134-2140.
 * 15) 	Oliver, B., Perrimon, N. and Mahowald, A. P. (1987) The ovo locus is required for sex specific germ line maintenance in Drosophila. Genes and Dev. 1, 913-923.
 * 16) 	Perrimon, N. (1988) The maternal effect of l(1)discs-large-1, a recessive oncogene in Drosophila melanogaster. Dev. Biol. 127, 392-407.
 * 17) 	Oliver, B., Perrimon, N. and Mahowald, A. P. (1988) Genetics evidence that the sans-fille locus is involved in Drosophila sex determination. Genetics 120, 159-171.
 * 18) 	Smouse, D., Goodman, C., Mahowald, A. P. and Perrimon, N. (1988) polyhomeotic: A gene required for the embryonic development of axon pathways in the central nervous system of Drosophila. Genes and Dev. 2, 830-842.
 * Ng, S-C., Perkins, L. A., Conboy, G., Perrimon, N. and Fishmann, M. (1989) A Drosophila gene expressed in the embryonic CNS shares one conserved domain with the mammalian GAP-43. Development. 105, 629-638.
 * 1) 	Perrimon, N., Engstrom, L., and  Mahowald, A. P. (1989) Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X-chromosome.  Genetics 121, 333-352.
 * 2) 	Perrimon, N., Smouse, D. T. and Miklos, G. L. G. (1989) Developmental genetics of loci at the base of the X-chromosome of Drosophila melanogaster. Genetics 121, 313-331.
 * 3) 	Perrimon, N., and Smouse, D. (1989) Multiple functions of a Drosophila homeotic gene, zeste-white 3, during segmentation and neurogenesis Dev. Biol. 135, 287-305.
 * 4) 	Klingensmith, J., Noll, E. and Perrimon, N. (1989) The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death. Dev. Biol. 134, 130-145.
 * 5) 	Ambrosio, L. Mahowald, A. P. and Perrimon, N. (1989) l(1)pole hole is required maternally for pattern formation in the terminal regions of the embryo. Development 106, 145-158.
 * 6) 	Ambrosio, L. Mahowald, A. P. and Perrimon, N. (1989) Requirement of the  Drosophila raf homologue for torso function. Nature 342, 288-291.
 * 7) 	Perkins, L. A., Doctor, J. S., Zhang, K., Stinson, L., Perrimon, N. and Craig. E. A. (1990) Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster. Mol. Cell. Biol. 10, 3232-3238.
 * 8) 	Smouse, D. T. and Perrimon, N. (1990) Genetic dissection of a complex neurological mutant, polyhomeotic, in Drosophila. Dev. Biol. 139, 169-185.
 * 9) 	Zhang, K., Chaillet, R., Perkins, L. A., Halazonetis, T. and Perrimon, N. (1990) Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells. P.N.A.S. 87, 6281-6285.
 * 10) 	Finkelstein, R., Smouse. D. T., Capaci, T., Spradling, A. C. and Perrimon, N. (1990) The orthodenticle gene encodes a novel homeodomain protein involved in the development of the Drosophila nervous system and ocellar visual structures. Genes and Dev. 4, 1516-1527.
 * 11) 	Finkelstein, R. and Perrimon, N. (1990) The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development. Nature 346, 485-488.
 * 12) 	Siegfried, E., Perkins, L. A., Capaci, T. M. and Perrimon, N. (1990) Putative protein kinase product of the Drosophila segment-polarity gene, zeste-white 3. Nature 345, 825-829.
 * 13) 	Zhang, K. Smouse, D. T. and N. Perrimon (1991) The crooked neck gene of Drosophila contains a motif found in a family of yeast cell cycle genes. Genes and Dev. 5, 1080-1091.
 * 14) 	Perrimon, N., Noll, E., McCall, K. and Brand, A. (1991) Generating lineage-specific markers to study  Drosophila development. Dev. Genet. 12, 238-252.
 * 15) 	Eberl, D. Perkins, L. A., Engelstein, M., Hilliker, A., and N. Perrimon. (1992) Developmental genetics of loci in region 17 of the X-chromosome of Drosophila melanogaster. Genetics 130, 569-583
 * 16) 	Kassis, J. A., Noll, E., VanSickle, E., Odenwald, W. and N. Perrimon. (1992) Altering the insertion specificity of a Drosophila transposable element. P.N.A.S. 89, 1919-1923.
 * 17) 	Chou T. B., and N. Perrimon (1992) Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics 131, 643-653.
 * 18) 	Perkins, L. A., Larsen, I., and Perrimon, N. (1992) corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell 70, 225-236
 * 19) 	Rutledge, B., Zhang, K., Bier, E., Jan, Y. N. and Perrimon, N. (1992) The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes and Dev.  6, 1503-1517.
 * 20) 	Wieschaus, E., Perrimon, N. and Finkelstein, R. (1992) orthodenticle activity is required for the development of medial structures in the larval and adult epidermis of Drosophila. Development 115, 801-811.
 * 21) 	Siegfried, E. Chou, T-B, and Perrimon, N. (1992) wingless signaling acts through zeste-white 3, the Drosophila homologue of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell 71, 1167-1179.
 * 22) 	Dang, D. T. and Perrimon, N (1992) Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila. Dev. Genetics. 13, 367-375.
 * 23) 	Lu, X. Chou T. B, Williams, N., Roberts, T. and Perrimon, N. (1993) Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila. Genes and Dev. 7, 621-632.
 * 24) 	Melnick, M. B. Perkins, L. A., Lee, M., Ambrosio, L. Perrimon, N. (1993) Developmental and molecular characterization of mutations in the Drosophila raf serine-threonine protein kinase. Development 118, 127-138.
 * 25) 	Brand, A. and Perrimon, N. (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
 * 26) 	Harrison, D. and Perrimon, N. (1993) Simple and efficient generation of marked clones in Drosophila. Current Biology. 3, 424-433.
 * 27) 	Melnick, M. B., Noll, E. and Perrimon, N. (1993) The Drosophila stubarista phenotype is associated with a dosage effect of the putative ribosome-associated protein D-p40 on spineless. Genetics  135, 553-564.
 * 28) 	Chou, T.-B., Noll, E. and Perrimon, N. (1993) Autosomal P[ovoD1] dominant female sterile insertions in Drosophila and their use in generating germline chimeras. Development 119, 1359-1369.
 * 29) 	van den Heuvel, M., Harryman-Samos, C., Klingensmith, J., Perrimon, N. and Nusse, R. (1993) Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO. J. 12, 5293-5303
 * 30) 	Siegfried, E., Wilder, E. and Perrimon, N. (1994) Components of wingless signaling in Drosophila. Nature 367, 76-80.
 * 31) 	Noordermeer, J., Klingensmith, J., Perrimon, N. and Nusse, R. (1994)dishevelled and armadillo are essential components of the wingless signaling pathway in Drosophila. Nature 367, 80-83.
 * 32) 	Klingensmith, J., Nusse, R. and Perrimon, N. (1994) The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes and Dev. 8, 118-130.
 * 33) 	Binari, R. and Perrimon, N. (1994) Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila. Genes and Dev. 8, 300-312.
 * 34) 	Brand, A. and Perrimon, N. (1994) Raf acts downstream of the EGF receptor to determine dorso-ventral polarity during Drosophila oogenesis. Genes and Dev. 8, 629-639.
 * Lu, X., Melnick, M.B., Hsu, J-C. and Perrimon, N. (1994). Genetics and molecular analysis of mutations involved in Drosophila-raf signal transduction. EMBO J. 13, 2592-2599.
 * 1) 	Hsu, J-C. and Perrimon, N. (1994). A temperature sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases. Genes and Dev. 8, 2176-2187.
 * 2) 	Sussman, D.J., Klingensmith, J., Salinas, P., Adams, P. S., Nusse, R. and Perrimon, N. (1994) Isolation and characterization of a mouse homolog of the Drosophila dishevelled segment polarity gene. Dev. Biol. 166, 73-86.
 * 3) 	Wilder, E.L. and Perrimon, N. (1995). Dual functions of wingless in the Drosophila leg imaginal disc. Development 121, 477-488.
 * 4) 	Hou, X.S., Chou, T.-B., Melnick, M. and Perrimon, N. (1995). The Torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell 81, 63-7.
 * 5) 	Sokol, S.Y., Klingensmith, J., Perrimon, N. and Itoh, K. (1995). Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development. 121, 1637-1647.
 * 6) 	Harrison, D.A., Binari, R., Nahreini, T. S., Gilman, M. and Perrimon, N. (1995) Activation of a Drosophila janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO. J. 14, 2857-2865.
 * 7) 	Rivera-Pomar, R., Lu, X., Perrimon, N., Taubert, H. and Jackle, H. (1995) Activation of posterior gap gene expression in the Drosophila blastoderm. Nature 376, 253-256.
 * 8) 	Yoffe, K., Manoukian, A., Wilder, E., Brand, A. and Perrimon, N. (1995) Evidence for engrailed-independent wingless autoregulation in Drosophila. Dev. Biol. 170, 636-650.
 * 9) 	Yin, J.C.P., Wallach, J.S., Wilder, E.L., Klingensmith, J., Dang, D., Perrimon, N., Zhou, H., Tully, T. and Quinn, W.G. (1995) ADrosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Mol. Cell. Biol. 15, 5123-5130.
 * 10) 	Manoukian, A.S., Yoffe, K., Wilder, E.L. and Perrimon, N. (1995) The porcupine gene is required for wingless autoregulation in Drosophila. Development 121, 4037-4044.
 * 11) 	Hou, X.S., Melnick, M.B. and Perrimon, N. (1996) marelle acts downstream of the Drosophila Hop/JAK kinase and encodes a protein similar to the mammalian STATs. Cell 84, 411-420.
 * 12) 	Cleghon, V., Gayko, U., Copeland, T.D., Perkins, L.A., Perrimon, N. and Morrison, D.K. (1996). Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes Dev. 10, 566-577.
 * 13) 	Axelrod, J., Matsuno, K., Artavanis-Tsakonas, S. and Perrimon, N. (1996). Dishevelled mediates interaction between Wingless and Notch signaling pathways. Science 271, 1826-1832.
 * 14) 	Musacchio M. and Perrimon N. (1996) The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expresed in the CNS. Dev Biol. 78, 63-76.
 * 15) 	Klingensmith, J., Yang Y., Axelrod J. D., Beier D. R., Perrimon N. and Sussman D. J. (1996) Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mech Dev. 58, 15-26.
 * 16) 	Perkins, L.A., Johnson, M.R., Melnick, M.B. and Perrimon, N. (1996). The non-receptor protein tyrosine phosphatase Corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Dev. Biol. 180, 63-81.
 * 17) 	Kadowaki, T., Wilder, E., Klingensmith, J., Zachary, K. and Perrimon, N. (1996). The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes and Dev. 15, 3116-3128.
 * 18) 	Rulifson, E.J., Micchelli, C.A., Axelrod, J.D., Halevy, M., Perrimon, N. and Blair, S. (1996). wingless refines its own expression domain on the Drosophila wing margin. Nature 384, 72-74.
 * 19) 	Chou, T.-B. and Perrimon, N. (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.
 * 20) 	Perrimon, N., Lanjuin, A., Arnold, C. and Noll, E. (1996). Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element induced mutations. Genetics 144, 1681-1692.
 * 21) 	Goode, S., Melnick, M.B., Chou, T.-B. and Perrimon, N. (1996). The role of Egghead during morphogenesis of the follicular cell epithelium. Development 122, 3863-3879.
 * 22) 	Hou, X.S. and Perrimon, S. (1997). The JAK/STAT pathway in Drosophila. TIG. 13, 105-110.
 * Yu, Y., Li, W., Su, K., Yssa, M., Han, W., Perrimon, N. and Pick, L. (1997). The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Fushi Tarazu. Nature 385, 552-554.
 * 1) 	Eberl, D., Lorenz, L.J., Melnick, M.B., F., Sood, V., Lasko, P. and Perrimon, N. (1997). A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycle. Genetics 146, 951-963.
 * 2) 	Hou, X.S., Goldstein, E.S. and Perrimon, N. (1997). Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes and Dev. 11, 1728-1737.
 * 3) Goode, S. and Perrimon, N. (1997).  Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis.  Genes and Dev. 11, 2532-2544.
 * 4) 	Haecker, U., Lin, X. and Perrimon, N (1997) The Drosophila Sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124, 3565-3523.
 * Li, W., Skoulakis, E.M.C., Davis, R.L. and Perrimon, N. (1997). The Drosophila 14-3-3 protein leonardo enhances torso signaling through D-raf in a Ras1-dependent manner. Development 124, 4163-4171.
 * 1) Eberl, D., Duyk, G.M. and Perrimon, N. (1997) A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. P.N.A.S. 94, 14837-14842.
 * 2) Haecker, U.  and Perrimon, N. (1998) The DRho- GEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes and Dev. 12, 274-284
 * 3)  Duffy, J.B., Harrison, D.A. and Perrimon, N. (1998). Identifying loci required for follicular patterning using directed mosaics. Development 125, 2263-2271.
 * 4) 	Bellaiche, Y., The, I. and Perrimon, N.(1998) Tout-velu, a Drosophila homologue of the putative tumor suppressor gene Ext-1, is required for the diffusion of the hedgehog protein. Nature 394, 85-88.
 * 5)  Perrimon, N. (1998) New advances in Drosophila provide opportunities to study gene functions. P.N.A.S. 95, 9716-9717.
 * 6)  Axelrod, J.D., Miller, J.R., Shulman, J.M., Moon, R.T. and Perrimon, N. (1998)    Differential recruitment of Dishevelled provides signaling specificity in the Wingless and  Planar Cell Polarity signaling pathways.  Genes and Dev. 12, 2610-2622.
 * 7)  Harrison, D.A., McCoon, P.E., Binari, R., Gilman, M. and Perrimon, N. (1998)
 * 1) Cleghon, V.,  Feldmann, P.,  Ghiglione, C., Copeland, T.D.,  Perrimon, N.,  Hughes, D.A., and Morrison, D.K. (1998).  Opposing actions of CSW and RasGAP modulate the 	strength of Torso RTK signaling in the Drosophila terminal pathway.  Molecular Cell 2, 719-727.
 * Li, W., Melnick, M. and Perrimon, N. (1998) Dual Function of Ras in Raf activation. Development 125, 4999-5008.
 * 1) Ghiglione, C., Perrimon, N., and Perkins, L. (1999) Quantitative variations in the level of MAPK activity controls patterning of the embryonic termini in Drosophila. Dev. Biol. 205, 181-193.
 * 2) Gayko, U., Cleghon, V., Copeland, T., Morrison, D. K., and Perrimon, N. (1999). Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso Receptor Tyrosine Kinase. P.N.A.S. 96, 523-528
 * 3) Ghiglione, C.,  Carraway, K.L.,  Amundadottir, L.T.,  Boswell, R.E.,  Perrimon, N.*, and Duffy, J.B.* (1999). The transmembrane molecule Kekkon 1 acts in a feed back loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis.* Co-senior and corresponding authors.Cell 96, 847-856.
 * 4) Zeidler, M. P., Perrimon, N. and Strutt, D.I.(1999). Polarity determination in the Drosophila eye: a novel role for Unpaired and JAK/STAT signalling. Genes 	and Development 13, 1342-1353
 * 5) Bellaiche, Y., Mogila, V. and Perrimon, N. (1999). I-SceI endonuclease, a new tool for studying DNA double stand break repair mechanisms in Drosophila. Genetics 152, 1037-1044.
 * 6) Lin, X., and Perrimon, N. (1999) Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signaling. Nature 400, 218-284.
 * 7) Lin, X., Buff, E.M., Perrimon, N., and Michelson, A.M. (1999) Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126, 3715-3723.
 * 8) The, I., Bellaiche, and Perrimon, N.  (1999) Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Molecular Cell 4, 633-640.
 * 9) Martin Blanco, E., Roch, F., Noll, E., Baonza, A., Duffy, J.B., and Perrimon, N. (1999) A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing. Development 126, 5739-5747.
 * 10) Zeidler, M. P., Perrimon, N. and Strutt, D.I. (1999) The four jointed gene is required in the Drosophila eye for ommatidial polarity specification. Current Biology 9, 1363-1372.
 * 11) Bilder, D. and Perrimon, N. (2000) Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature  403, 676-680.
 * 12) Bilder, D., Li, M. and Perrimon, N. (2000) Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289, 113-116.
 * 13) Baum, B., Li, W. and Perrimon, N. (2000)  A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Current Biology 10, 964-973.
 * Li, W., Noll, E. and Perrimon, N. (2000) Identification of autosomal regions involved in Drosophila Raf function. Genetics 156, 763-774.
 * 1) Noll, E., Medina, M., Hartley, D., Zhou J., Perrimon, N and Kosik. K. S. (2000) Presenilin Affects Arm/b-Catenin Localization and Function in Drosophila. Dev Biol. 227, 450-464.
 * 2) Tanaka, K., Okabayashi, K., Asashima, M., Perrimon, N. and Kadowaki, T. (2000)
 * 1) Zeidler, M. P., Perrimon, N. and Strutt, D.I.(2000) Multiple roles for four jointed in planar polarity and limb patterning. Dev Biol. 228, 181-196
 * 2) Baeg, G. H., Lin, X., Khare, N., Baumgartner, S. and Perrimon, N. (2001) Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 128, 87-94.
 * 3) Bai, J. M., Wang, J. C., Chiu, W.S., Perrimon, N. and Hsu, J.C. (2001) The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway. Development 128, 591-601
 * 4) Baum, B. and Perrimon, N. (2001)  Spatial organization of the actin cytoskeleton in Drosophila epithelial cells. Nature Cell Biology 3, 883-890.
 * 5) Selva, E., Hong, K., Baeg, G. H., Beverley, S. M., Turco, S. J., Perrimon, N. and Haecker, U. (2001) Dual Role of the fringe connection gene in both Heparan Sulfate and fringe-dependent signaling events. Nature Cell Biology 3, 809-815.
 * 6) Stronach, B. E. and Perrimon, N. (2001) Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo.
 * 1) Suzanne, M., Perrimon, N. and Noselli, S. (2001). The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle. Dev Biol. 237, 282-294.
 * 2) Hong, Y., Stronach, B., Perrimon, N, Jan, L. Y. and Jan, Y. N. (2001) Drosophila stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts in Drosophila. Nature 414, 634-638.
 * 3) Ghiglione, C., Bach, E., Paraiso, Y., Carraway, K., Noselli, S. and Perrimon, N. (2002) Mechanism of activation of the Drosophila EGF Receptor by the TGFα ligand Gurken during oogenesis. Development 129, 175-186
 * 4) Stronach, B. E. and Perrimon, N. (2002) Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper. Genes and Development 16, 377-387
 * 5) Chen, H.W., Marinissen, M. J., Oh, S.W., Chen, X., Melnick, M., Perrimon, N. Gutkind, J.S., and Hou, S. X. (2002) CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila. Mol. Cell. Biol. 6, 1792-1803.
 * 6) Micchelli, C., The, I. Selva, E., Mogila, V. and and Perrimon, N. (2002) Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling. Development 129, 843-851
 * 7) Mathew, D., Gramates, L. S., Packard, M., Packard, U., Thomas, U., Bilder, D., Perrimon, N., Gorczyca, M., and Budnick, V. (2002) Recruitment of Scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Current Biology 12, 531-539.
 * 8) Schöck, F., and Perrimon, N. (2002) Cellular processes associated with germ band retraction in Drosophila. Developmental Biology 248, 29-39.
 * Li, W., Agaisse, H., Mathey-Prevot, B. and Perrimon, N. (2002) Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila. Development 129, 4241-4248.
 * 1) Hrdlicka, L., Gibson, M., Kiger, A., Micchelli, C., Schober, M., Schöck, F. and Perrimon, N. (2002) Analysis of twenty four Gal4 lines in Drosophila melanogaster. Genesis 34, 51-57.
 * 2) Boutros, M., Agaisse, H. and Perrimon, N. (2002) Sequential activation of signaling pathways during innate immune responses in Drosophila. Developmental Cell 3, 711-722.
 * 3) Song. H-J., Billeter, J-C., Reynaud, E., Carlo, T., Spana, E. P., Perrimon, N., Goodwin, S. F., Baker, B. S. and Taylor, B. J. (2002)  The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila. Genetics 162, 1703-1724.
 * 4) Wills, Z., Emerson, M., Rusch, J., Bikoff, J., Baum, B., Perrimon, N. and Van Vactor, D. (2002) A Drosophila homologue of Cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron 36, 611-622.
 * 5) Tan, C., Stronach, B., and Perrimon, N. (2003) Roles of Myosin Phosphatase during Drosophila development. Development 130, 671-681.
 * 6) Bilder, D., Schober, M. and Perrimon, N. (2003) Integrated activity of PDZ protein complexes regulates epithelial polarity. Nature Cell Biology 5, 53-58.
 * 7) Schöck, F. and Perrimon, N. (2003) Retraction of the Drosophila germ band requires cell-matrix interaction. Genes and Development 17, 597-602.
 * 8) Micchelli, C., Esler, W. P., Kimberly, W. T., Jack, C., Berezovska, O.,  Kornilova, A., Hyman, B. T., Perrimon, N. and Wolfe, M. S. (2003) γ-Secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. FASEB Journal 17, 79-81.
 * 9) Adam, G., Perrimon, N. and Noselli, S. (2003) The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila. Development 130, 2397-2406.
 * 10) Bashirullah, A., Pasquinelli, A. E., Kiger, A., Perrimon, N., Ruvkun, G. and Thummel, C. S. (2003) Coordinate regulation of small temporal RNAs at the onset of Drosophila  metamorphosis. Dev. Biol. 259, 1-8.
 * 11) Lüders, F., Segawa, H., Stein, D., Selva, E. M., Perrimon, N., Turco, S. J. and Häcker, U. (2003) slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila. EMBO J. 22, 3635-3644.
 * 12) Ghiglione, G., Amundadottir, L., Andresdottir, M., Bilder, D., Diamonti, J. A., Noselli., Perrimon. N. and Carraway III, K. L. (2003) Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.  Development 130, 4483-4493
 * 13) Agaisse, H., Petersen, U-M., Boutros, M., Mathey-Prevot, B. and Perrimon, N. (2003) Signaling Role of Hemocytes in Drosophila JAK/STAT-Dependent Response to Septic Injury. Developmental Cell 5, 441-450
 * 14) Sasamura, T., Sasaki, N., Miyashita, F., Nakao, S., Ishikawa, H. O., Ito, M., Kitagawa, M., Harigaya, K., Spana, E., Bilder, D., Perrimon, N. and Matsuno, K. (2003) neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase homolog that is essential for Notch-Delta interactions. Development 130, 4785-4795.
 * 15) Bach, E. A., Vincent. S., Zeidler. M. and Perrimon, N. (2003) A sensitized genetic screen to identify novel regulators and components of the Drosophila Janus Kinase/Signal Transducer and Activator of Transcription Pathway. Genetics 165, 1149-1166.
 * 16) Kiger, A. A., Baum, B., Jones, S., Jones, M. R., Coulson, A., Echeverri, C. and Perrimon, N. (2003) A functional genomic analysis of cell morphology using RNA-interference. Journal of Biology 2 (4).
 * 17) Cherry, S. and Perrimon, N. (2004) Entry is a rate-limiting step for viral infection in a Drosophila model for pathogenesis. Nature Immunology 5, 81-87.
 * 18) Boutros, M., Kiger, A. A., Armknecht, S., Kerr, K. Hild, M., Koch, B., Haas, S. A., Heidelberg Fly Array Consortium., Paro, R., and Perrimon, N. (2004) Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells. Science 303. 832-835.
 * 19) Zeidler, M., Tan, C., Bellaiche, Y., Cherry, S., Häder, S., Gayko, U. and Perrimon, N. (2004) Temperature-sensitive control of protein activity by conditionally splicing inteins. Nature Biotechnology 22. 871-879.
 * 20) Brückner, K.,  Kockel, L., Duchek, P.,  Luque, C. M., Rørth, P., and Perrimon, N. (2004) The PDGF/VEGF Receptor Controls Blood Cell Survival in Drosophila. Developmental Cell 7. 73-84.
 * 21) Sinenko, S. A., Kim, E-K., Wynn, R., Manfruelli, P., Ando, I., Wharton, K. A., Perrimon. N.  and Mathey-Prevot. B. (2004) Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Dev. Biol, 273, 48-62.
 * 22) Schlesinger, A., Kiger, A., Perrimon, N. and  Shilo, B-Z. (2004) Small wing PLCg is required for ER retention of cleaved Spitz during eye development in Drosophila. Developmental Cell 7, 535-545.
 * 23) Eggert, U. S., Kiger, A. A., Richter, C., Perlman, Z. E., Perrimon,N., Mitchison, T. J. and Field, C. M. (2004) Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLOS Biology 2. e379.
 * 24) Baeg, G. H., Selva, E., Goodman, R., Dasgupta, R. and Perrimon, N. (2004) The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycans receptors. Dev Biol. 276. 89-100.
 * 25) Cherry, S., Doukas. T., Armknecht, S., Whelan, S., Wang, H., Sarnow, P. and Perrimon, N. (2005) Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes and Development 19. 445-452.
 * 26) Gibson, M. C. and Perrimon, N. (2005) Extrusion and death of DPP/BMP- compromised epithelial cells in the developing Drosophila wing imaginal epithelium. Science 307. 1785-1789.
 * 27) Hayward, P., Brennan, K.,  Sanders, P.,  Balayo, T., Dasgupta, R.,  Perrimon, N.  and Martinez Arias, M. (2005) Notch modulates Wnt signalling by associating with Armadillo/ß-catenin and regulating its transcriptional activity. Development 132. 1819-1830.
 * 28) Dasgupta, R., Kaykas, A., Moon, R. T. and Perrimon,  N. (2005) Functional genomic analysis of the Wnt-Wingless signaling pathway. Science 308. 826-832.
 * 29) Schober, M., Rebay, I. and Perrimon, N. (2005) Function of the ETS transcription factor Yan in border cell migration. Development 132. 3493-3504.
 * 30) Philips, J., Rubin, E. and Perrimon, N. (2005) Drosophila RNAi screen reveals CD36 family member required for Mycobacterial infection. Science 309. 1251-1253.
 * 31) Agaisse, H., Burrack, L., Philips, J., Rubin, E., Perrimon, N. and Higgins, D. E.  (2005) Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science 309, 1248-1251.
 * 32) Baeg, G. H., Zhou, R. and Perrimon, N. (2005) Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes and Development 19. 1861-1870. Addendum  in Genes and Development (2007) 21. 875-877.
 * 33) Zhou, X., Liu, K.Y., Bradley, P., Perrimon, N., and Wong, S. T. (2005) Towards automated cellular image segmentation for RNAi genome-wide screening. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 8, 885-92.
 * 34) Nybakken, K., Vokes, S. S., Lin, T-Y., McMahon, A. P. and Perrimon, N. (2005) Genome-wide RNA interference screening identifies many new genes with roles in Hedgehog signaling. Nature Genetics. 37. 1323-1332.
 * 35) Kirilly, D., Spana, E., Perrimon, N., Padgett, R. W., and Xie, T. (2005) BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary. Developmental Cell. 9, 651-662.
 * 36) Flockhart, I., Booker, M., Kiger. A., Boutros, M., Armknecht, S., Ramadan, N., Richardson, K., Xu, A., Perrimon, N. and Mathey-Prevot. B. (2006) FlyRNAi: The Drosophila RNAi Screening Center Database. Nucleic Acid Research. D489-94.
 * 37) Micchelli, C. and Perrimon, N. (2006) Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature. 439, 475-479.
 * 38) Bard, F., Casano, L., Mallabiabarrena, A., Wallace, E., Saito, K., Kitayama, H., Guizzunti, G., Hu, Y., Wendler, F., DasGupta, R., Perrimon, N. and Malhotra, V. (2006) Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature. 439. 604-607.
 * 39) Karsten, P., Plischke, I., Perrimon, N. and Zeidler, M. P. (2006) Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E. Cellular Signaling 18, 819-829.
 * 40) Chen, L-Y., Wang, J-C., Hyvert, Y., Lin. H-P., Perrimon, N., Imler, J-L. and Hsu, J-C. (2006) Weckle is a Zinc Finger adaptor of the Toll pathway in dorsoventral patterning of the Drosophila Embryo. Current Biology 16. 1183-1193.
 * 41) Gibson, M. C. Patel, A., Nagpal, R. and Perrimon, N. (2006) The emergence of geometric order in proliferating metazoan epithelia. Nature 442. 1038-1041.
 * 42) Kulkarni, M. M., Booker M., Silver, S., Friedman, A., Hong, P., Perrimon, N., and Mathey-Prevot, B. (2006) Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nature Methods 3. 833-838.
 * 43) Friedman, A. and Perrimon, N. (2006) A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signaling. Nature 444, 230-234.
 * 44) Bach, E. A., Ekas, L. A., Ayala-Camargo, A., Flaherty, M. S., Lee, H. Perrimon, N. and Baeg, G-H. (2007) GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo. Gene Expression Patterns 7, 323-331.
 * 45) Cherry, S., Kunte, A., Wang, H., Coyne, C., Rawson, R. H. and Perrimon, N. (2006) COPI activity coupled with fatty acid biosynthesis is required for viral replication. PLoS Pathog 2(10): e102. DOI: 10.1371/journal.ppat.0020102.
 * Lu, J. Ruhf, M-L., Perrimon, N. and Leder, P. (2007) A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. PNAS. 104, 9381-9386.
 * 1) Bakal, C., Aach, J., Church, G. and Perrimon, N. (2007) Quantitative morphological signatures define local signaling networks regulating cell morphology. Science 316, 1753-1756.
 * 2) DasGupta, R., Nybakken, K., Booker, M., Mathey-Prevot, B.,  Gonsalves, F.,  Changkakoty, B. and Perrimon, N. (2007) A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. Genome Biology. 8. R203.
 * 3) Silver, S. J., Hagen, J. W., Okamura, K., Perrimon, N. and Lai, E. C. (2007) Functional screening identifies miR-315 as a potent activator of Wingless signaling. PNAS. 104, 18151-18156.
 * 4) Bai, J., Hartwig, J. H., and Perrimon, N. (2007) SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth. Developmental Cell 13, 828-842.
 * 5) Vinegoni, C., Pitsouli, C., Razansky, D., Perrimon, N. and  Ntziachristos, V. (2008) In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nature Methods 5, 45-47.
 * Ni, J-Q., Markstein, M., Binari, R., Pfeiffer, B., Liu, L-P., Villalta, C., Booker, M., Perkins, L. A., and Perrimon, N. (2008) Vector and Parameters for Targeted Transgenic RNAi in Drosophila melanogaster. Nature Methods 5, 49-51.
 * 1) Wang, J., Zhou, X., Bradley, P. L., Chang, S. F., Perrimon, N. and Wong, S. T. (2008) Cellular phenotype recognition for high-content RNA interference genome-wide screening. J. Biomol. Screen. 13, 29-39.
 * 2) Philips, J. A., Porto, M.C., Wang, H., Rubin, E. J., and Perrimon, N. (2008) ESCRT factors restrict mycobacterial growth. PNAS. 105, 3070-3075.
 * 3) Bai, J., Binari, R., Ni, J-Q., Vijayakanthan, M.. Li, H-S. and Perrimon, N. (2008) RNA interference screening in Drosophila primary muscle cells for genes involved in muscle assembly and maintenance. Development.  135, 1439-1449.
 * 4) Markstein, M., Pitsouli, C., Villalta, C., Celniker, S. and Perrimon, N. (2008) Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nature Genetics. 135, 1439-1449.
 * 5) Czech, B., Malone, C. D., Zhou, R., Stark, A., Schlingeheyde, C., Dus, M., Perrimon, N., Kellis, M., Wohlschlegel, J. A., Sachidanandam, R., Hannon, G. H. and Brennecke, J. (2008) An endogenous small interfering RNAi pathway in Drosophila. Nature. 453, 798-802.
 * 6) Yin, Z., Zhou, X., Bakal, C., Li., F., Sun, Y., Perrimon, N. and Wong, S. T. C. (2008) Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. BMC Bioinformatics 9: 264.
 * 7) Sepp, K. J., Hong, P., Lizarraga, S. B., Liu, J. S., Mejia, L. A., Walsh, C. A. and Perrimon, N. (2008) Identification of neural outgrowth genes using genome-wide RNAi. PLoS Genetics. 7: e1000111.
 * 8) Wang, J., Zhou, X., Li, F., Bradley, P. L., Chang, S. F., Perrimon, N. and Wong, S. T. (2008) An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling. J Biomed Inform. PMID: 18547870.
 * 9) Vincent, S., Perrimon, N. and Axelrod, J. D. (2008) Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning. Development. 135, 2767-2775
 * 10) Bakal, C.,Linding, R., Llense, F., Heffern, E., Martin-Blanco, E.,Pawson, T. andPerrimon, N. 28 Phosphorylation Networks Regulating JNK Activity in Diverse Genetic Backgrounds. Science. 322, 453-456.
 * 11)  Zhou, R., Hotta, I., Denli, A.M., Hong, P., Perrimon, N. and Hannon, G. J. (2008) Comparative analysis of Argonaute-dependent small RNA pathways in Drosophila. Molecular Cell. 4, 592-599.
 * 12) Demontis, F. and Perrimon, N. (2009) Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Development. 136, 983-993. PMID: 19211682.
 * 13) Zhang, S., Feany, M. B., Saraswati, S., Littleton, T. and Perrimon, N. (2009) Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington’s disease model. Disease Models and Mechanisms. 2, 247-266. PMID: 19380309.
 * Ni, J-Q., Liu, L-P., Binari, R., Hardy, R., Shim, H-S., Cavallaro, A., Booker, M., Pfeiffer, B., Markstein, M., Wang, H., Villalta, C., Laverty, T. R., Perkins, L. A. and Perrimon, N. (2009) A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics. 182, 1089-1100. PMID: 19487563.
 * 1) Kaplow, I., Singh, R., Friedman, A., Bakal, C., Perrimon, N., and Berger, B. (2009) RNAiCut: automated detection of significant genes from functional genomic screens. Nature Methods. 6, 476-477. PMID: 19564846.
 * 2) Celniker, S.E., Dillon, L. A., Gerstein, M.B., Gunsalus, K.C., Henikoff, S., Karpen, G.H., Kellis, M., Lai, E.C., Lieb, J.D., MacAlpine, D.M., Micklem, G., Piano, F., Snyder, M., Stein, L., White, K.P., Waterston, R.H., and modENCODE Consortium. (2009) Unlocking the secrets of the genome. Nature. 459, 927-30.
 * 3) Griffin, R., Sustar, A., Bonvin, M., Binari, R., del Valle Rodriguez, A., Hohl, A. M., Bateman, J., Villalta, C., Heffern, E., Grunwald, D., Bakal, C., Desplan, C., Schubiger, G., Wu, C. T. and Perrimon, N. (2009) The Twin Spot Generator for differential  Drosophila lineage analysis. Nature Methods. 6, 600-602. PMID: 19633664.
 * 4) Brouzes, E., Medkova, M., Savenelli, N., Marran, D., Twardowski, M., Hutchison, J. B., Rothberg, J. M., Link, D. R., Perrimon, N. and Samuels, M. L. (2009) Droplet microfluidic technology for single-cell high-throughput screening. PNAS. 106, 14195-200. PMID: 19617544.
 * 5) Zhou, R., Czech, B., Brennecke, J., Sachidanandam, R., Wohlschlegel, J. A., Perrimon, N. and Hannon, G. J. (2009) Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA. 15, 1886-1895. PMID: 19635780.
 * 6) Kondo, S., Booker, M. and Perrimon, N. (2009) Cross-species RNAi rescue platform in Drosophila melanogaster. Genetics. 183, 1165-1173. PMID: 19720858.
 * 7) Czech, B., Zhou, R., Erlich, Y., Brennecke, J., Binari, R., Villalta, C., Gordon, A., Perrimon, N. and Hannon, G. J. (2009) Hierarchical rules for Argonaute loading in Drosophila. Molecular Cell. 36, 445-456. PMID: 19917252.
 * 8) Yang, X., Friedman, A., Nagpal, S., Perrimon, N., and Asara, J. M. (2009) Use of a Label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in Insulin signaling. J Biomol Tech. 20, 272-277. PMID: 19949701.
 * 9) Apidianakis, Y., Pitsouli, C., Perrimon, N. and Rahme, L. (2009) Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. PNAS. PMID: 19934041.
 * 10) Nir, O., Bakal, C., Perrimon, N., and Berger, B. (2010) Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial genetic screen. Genome Research. 20, 372-380. PMID: 20144944.
 * 11) Zhang, S., Binari, R., Zhou, R., and Perrimon, N. (2010) A genome-wide RNAi screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. Genetics. PMID: 20100940.
 * 12) Kockel, L., Kerr, K. S., Melnick, M., Brueckner, K., Hebrok, M.  and Perrimon, N. (2010) Dynamic switch of negative feedback regulation in Drosophila Akt-Tor signaling. PloS Genetics 6, e1000990. PMID: 20585550.
 * 13) Schnall-Levin, M., Zhao, Y., Perrimon, N. and Berger, B. (2010) Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3’UTRs. PNAS. 107, 15751-6. PMID: 20729470.
 * 14) Yan, H., Venkatesan, K., Beaver, J. E., Klitgord. N., Yildirim, M. A., Hao, T.,  Hill, D. E., Cusick, M. E., Perrimon, N., Roth, F. P.,  and Vidal, M. (2010) A genome-wide gene function prediction resource for Drosophila melanogaster. PLoS One 5, pii: e12139. PMID: 20711346.
 * 15) Pitsouli, C. and Perrimon, N. (2010) Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis. Development. 137, 3615-3624. PMID: 20940225.
 * 16) Karpowicz, P., Perez, J. and Perrimon, N. (2010) The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development. 137, 4135-4145. PMID: 21098564
 * 17) Rui, Y.,  Bai, J. and Perrimon, N. (2010). Sarcomere formation occurs by the assembly of multiple latent protein complexes. PLoS Genetics. 6: e1001208. PMID: 21124995.
 * 18) Demontis, F. and Perrimon, N. (2010) FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell. 143, 813-825. PMID: 21111239.
 * 19) modENCODE Consortium (2010) Identification of functional elements and regulatory circuits by Drosophila modEncode. Science 330, 1787-1797. PMID: 21177974.
 * 20) Cherbas, L., Willingham, A., Zhang, D., Yang, L., Zou, Y., Eads, B. D., Carlson, J. W., Landolin, J. M., Kapranov, P., Dumais, J., Samsonova, A., Choi, J-H., Roberts, J., Davis, C. A., Tang, H., van Baren, M. J., Ghosh, S., Dobin, A., Bell, K., Lin, W., Langton, L., Duff, M. O., Tenney, A. E., Zaleski, C., Brent, M. R., Hoskins, R. S., Kaufman, T. C., Andrews, J., Graveley, B. R., Perrimon, N., Celniker, S. E., Gingeras, T. R. and Cherbas, P. (2011) The transcriptional diversity  of 25 Drosophila cell lines.  Genome Research. 21, 301-314. PMID: 21177962.
 * 21) Graveley, B. R. Brooks A. N., Carlson, J. W., Duff, M. O., Landolin, J., Yang, L.,  Artieri, C. G., van Baren, M. J.,  Boley, N., Booth, B. W., Brown, J. B., Cherbas, L., Davis, C. A., Dobin, A.,  Bell, K., Li, R., Lin, W., Malone, J. H., Mattiuzzo, N. R., Miller, D., Sturgill, D., Tuch, B., Zaleski, C., Zhang, D.,  Blanchette, M., Dudoit, S., Eads, B., Green, R. E., Hammonds, A., Jiang, L., Kapranov, P., Langton, L., Perrimon, N., Sandler, J. E., Wan, K/ H., Willingham, A., Zhang, Y., Zou, Y., Andrews, J.,  Bickel, P.,   Brenner, S. E., Brent, M. R., Cherbas, P., Gingeras, T. R., Hoskins, R. A., Kaufman, T. C., Oliver, B., and Celniker, S. E. (2011) The Developmental Transcriptome of Drosophila melanogaster. Nature 471. 473-479.PMID: 21179090.
 * 22) Berezikov, E., Robine, N., Samsonova, A., Westholm, J. O., Naqvi, A., Hung, J-H., Okamura, K., Dai, Q., Bortolamiol-Becet, D., Martin, R., Zhao, Y., Zamore, P. D., Hannon, G. J., Marra, M. A., Weng, Z., Perrimon, N. and Lai E. C. (2011) Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Research. 21. 203-215. PMID: 21177969.
 * 23) Kondo, S and Perrimon, N. (2011) A genome-wide RNAi screen identifies core components of the G2-M DNA damage checkpoint. Science Signaling. 4, rs1. PMID: 21205937.
 * 24) Booker, M., Samsonova, A., Kwon, Y., Flockhart, I., Mohr, S., and Perrimon, N. (2011) False negative rates in Drosophila cell-based RNAi screens: A case study. BMC Genomics. 12, 50. PMID: 21251254.
 * 25) Micchelli, C. A., Sudmeier, L., Perrimon, N., Tang, S. and Beehler-Evans, R. (2011) Identification of adult midgut precursors in Drosophila. Gene Expression Patterns. 1-2, 12-21. PMID: 20804858.
 * 26) Gibson, W. T., Veldhuis, J. H., Rubinstein, B., Cartwright, H. N., Perrimon, N., Brodland, G. W., Nagpal, R. and Gibson, M. C. (2011) Control of mitotic cleavage plane by local epithelial cell topology. Cell. 144, 427-438. PMID: 21295702.
 * 27) Chan, W. M., Tsoi, H., Wu, C. C., Wong, C. H., Cheng, T. C., Li, H. Y., Lau, K. F., Shaw, P. C., Perrimon, N. and Chan, H. Y. E. (2011) Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Hum. Mol. Genet. 20, 1738-50. PMID 21300695.
 * Ni, J-Q., Zhou, R., Czech, B., Liu, L-P., Holderbaum, L., Yang-Zhou, D., Shim, H-S., Tao, R., Handler, D., Karpowicz, P., Binari, R., Booker, M., Brennecke, J., Perkins, L. A. Hannon, G. J. and Perrimon, N. (2011) A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods 8, 405-7. PMID: 21460824.
 * 1) Schnall-Levin, M., Rissland, O. S., Johnston, W., Perrimon, N., Bartel, D. P. and Berger, B. (2011) Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs. Genome Research 21, 1395-1403. PMID: 21685129.
 * 2) Rohn J. L., Sims, D., Liu, T., Fedorova, M., Schoeck, F.,  Dopie, J., Vartiainen, M., Kiger, A. A., Perrimon, N. and  Baum, B.  (2011) Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype.  J. Cell Biol. 194, 789-805. PMID: 21893601.
 * Hu, Y., Flockhart, I., Vinayagam, V., Bergwitz, C., Berger, B., Perrimon, N. and Mohr, S. E. (2011) An Integrative Approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics. 12. 357. PMID: 21880147.
 * 1) Friedman, A. A., Tucker, G., Singh, R., Yan, D., Vinayagam, A., Hu, Y., Binari, R., Hong, P., Sun, X., Porto, M., Pacifico, S., Murali, T., Finley, R., Asara, J. M., Berger, B. and Perrimon, N. (2011) Proteomic and functional genomic landscape of receptor tyrosine kinase and Ras to extracellular signal–regulated kinase signaling. Science Signaling. 4, rs10. PMID: 22028469.
 * 2) Neumüller, R. A., Wirtz-Peitz, F., Lee, S., Kwon, Y., Buckner, M., Hoskins R, A., Venken, K., Bellen, H., Mohr, S. and Perrimon, N. (2012) Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 190, 931-940. PMID: 22174071.
 * 3) Flockhart, I. T., Booker, M., Hu, Y., 1, McElvany, B., Gilly, Q., Mathey-Prevot, B., Perrimon, N. and Mohr, S. (2012). FlyRNAi.org—the database of the Drosophila RNAi Screening Center: 2012 Update. Nucleic Acid Research. 40, D715-9. PMID: 22067456.
 * 4) Bergwitz, C., Rasmussen, M. D., DeRobertis, C., Wee, M. J., Sinha, S., Chen, H. H., Huang, J. and Perrimon, N. (2012) Roles of major facilitator superfamily transporters in phosphate response in Drosophila. PloS ONE. 7(2):e31730. PMID: 22359624.
 * 5) Bejarano, F., Bortolamiol-Becet, D., Dai, Q., Sun, K., Saj, A., Chou, Y-T., Raleigh, D. R., Kim, K., Ni, J., Duan, H., Yang, J-S., Fulga, T. A., Van Vactor, D., Perrimon, N. and Lai, E. C. (2012) A genome-wide transgenic resource for conditional expression of Drosophila microRNAs. Development. 139, 2821-2831. PMID: 22745315.
 * 6) Kusche-Gullberg, M., Nybakken, K., Perrimon, N. and Lindahl, U. (2012) Drosophila heparan sulfate – a novel design. Journal of Biological Chemistry. 16, 97-103. PMID:22768842.
 * 7) Katewa, S. D., Demontis, F., Kolipinski, M., Hubbard, A., Gill, M. S., Perrimon, N., Melov, S. and Kapahi, P. (2012) Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metabolism. 16, 97-103. PMID: 22768842.
 * 8) Stender, J. D., Pascual, G., Liu, W., Kaikkonen, M. U., Do, K., Spann, N., Boutros, M., Perrimon, N., Rosenfeld, M. G. and Glass, C. K. (2012) Control of pro-Inflammatory gene programs by regulated trimethylation and demythelation of histone H4K20. Molecular Cell. 48, 28-38. PMID: 22921934.
 * 9) Hosur, R., Peng, J., Arunachalam, V., Stelzl, U., Xu, J., Perrimon, N., Bienkowska, J. and Berger, B. (2012) Coev2Net: computational framework for boosting confidence in high-throughput protein-protein interaction datasets. Genome Biology. 3, R76. PMID: 22937800.
 * 10) Rajan, A. and Perrimon, N. (2012) Drosophila cytokine Unpaired 2 regulates physiological homeostasis by remotely controlling Insulin secretion. Cell. 151, 123-137. PMID: 23021220.
 * 11) Staller, M. V., Yan, D., Randklev, S., Bragdon, M. D., Wunderlich, Z. B., Tao, R., Perkins, L. A., DePace, A. H. and Perrimon, N. (2013) Depleting gene activities in early Drosophila embryos with the “maternal-Gal4-shRNA” system. Genetics.  193, 51-61. PMID: 23105012.
 * 12) Yeh, J.T.-H., Binari, R., Gocha, T., Dasgupta, R. and Perrimon, N. (2013) PAPTi: A Peptide Aptamer Interference Toolkit for perturbation of protein-protein interaction network. Scientific Reports. 3, 1156. PMID: 23362456.
 * 13) Bergwitz, C., Wee, M. J., Sinha, S., Huang, J., DeRobertis, C., Mensah, L., Cohen, J., Friedman, A., Kulkarni, M., Hu, Y., Vinayagam, A., Schnall-Levin, M., Berger, B., Perkins, L. A., Mohr, S. E., and Perrimon, N. (2013) Genetic determinants of phosphate response in Drosophila. PLoS ONE 8, e56753. PMID: 23520455.
 * 14) Pitsouli, C. and Perrimon, N. (2013) The homeobox transcription factor Cut coordinates patterning and growth during Drosophila airway remodeling. Science Signaling. 6, ra12. PMID: 23423438.
 * 15) Roti, G., Carlton, A., Ross, K. N., Markstein, M., Pajcini, K., Su, A. H., Perrimon, N., Pear, W. S., Kung, A. L., Blacklow, S. C., Aster, J. C., Stegmaier, K. (2013) Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell. 23, 390-405. PMID: 23434461.
 * 16) Vinayagam, A., Hu, Y., Kulkarni, M., Roesel, C., Sopko, R., Mohr, S. E. and Perrimon, N. (2013) Protein complex−based analysis framework for high-throughput data sets. Science Signaling. 6, rs5. PMID: 23443684.
 * 17) Karpowicz, P., Zhang, Y., Hogenesh, J. B., Emery, P. and Perrimon, N. (2013) The circadian clock gates the intestinal stem cell regenerative state. Cell Reports. 3, 996-1004. PMID: 23583176.
 * 18) Silva-Ayala, D., López, T., Gutiérrez, M., Perrimon, N., López, S., and Arias, C. F. (2013) Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry. PNAS. PMID: 23733942.
 * 19) Yin, Z., Sadok, A., Sailem, H.,  McCarthy, A.,  Xia, X.,  Li, F., Arias Garcia, M.,  Evans, L., Barr, A.,  Perrimon, N., Marshall, C.,  Wong, S. T. C. and Bakal, C.  (2013) A screen for morphological complexity identifies evolutionary conserved regulators of discrete switch-like morphogenesis. Nature Cell Biology. 15, 860-871. PMID:23748611.
 * Hu, Y., Roesel, C., Flockhart, I., Perkins, L., Perrimon, N. and Mohr, S. (2013) UP-TORR: online tool for accurate and up-to-date annotation of RNAi reagents. Genetics. 195, 37-45. PMID:23792952
 * Hu, Y., Sopko, R., Foos, M., Kelley, C., Flockhart, I., Ammeux, N., Wang, X., Perkins, L., Perrimon, N. and Mohr, S. (2013) FlyPrimerBank: An online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi Reagents. G3. 3, 1607-16. PMID: 23893746
 * 1) Neumüller, R. A., Gross, T., Samsonova, A. A., Vinayagam, A., Buckner, M., Founk, K., Hu, Y., Sharifpoor, S., Rosebrock, A. P., Andrews, B., Winston, F. and Perrimon, N. (2013) Conserved regulators of nucleolar size revealed by global phenotypic analyses. Science Signaling. 6, ra70. PMID:23962978
 * 2) Zirin, J., Cheng, D., Dhanyasi, N., Cho, J., Dura, J-M., VijayRaghavan, K. and Perrimon, N. (2013) Ecdysone signaling at metamorphosis triggers apoptosis of Drosophila abdominal muscles. Dev. Biol. 383, 275-84. doi:pii: S0012-1606(13)00483-1. PMID: 24051228
 * 3) Shulman, J.M., Imboywa, S., Giagtzoglou, N., Powers, M. P., Hu, Y., Devenport, D., Chipendo, P., Chibnik, L. B., Diamond, A., Perrimon, N., Brown, N. H., De Jager, P. L. and Feany, M. B. (2013) Functional screening in Drosophila  identifies Alzheimer’s disease susceptibility genes and  implicates Tau-mediated mechanisms. Human Molecular Genetics.  PMID: 24067533.
 * 4) Xiong, X-P., Kurthkoti, K.,  Chang, K-Y., Lichinchi, G., De, N., Schneemann, A., Macrae, I. J., Rana, T. M., Perrimon, N. and Zhou, R. (2013). Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. PNAS. 110, 16520-5. PMID: 24067655.
 * 5) Owusu-Ansah, E., Song, W. and Perrimon, N. (2013) Muscle mitohormesis promotes longevity via systemic repression of Insulin signaling. Cell. 155, 699-712. PMID: 24243023.
 * 6) Kwon, Y., Arunachalam, V., Sun, X., Dephoure, N., Gygi, S. P., Hong, P. and Perrimon, N. (2013) The Hippo signaling pathway interactome. Science. 342, 737-40. PMID: 24114784.
 * 7) Ren, X., Sun, J., Housden, B., Hu, Y., Roesel, C., Lin, S., Liu, L-P., Yang, Z., Mao, D., Sun, L., Wu, Q., Ji, J-Y., Xi, J., Mohr, S., Xu, J., Perrimon, J., and Ni, J-Q. (2013) Optimized gene editing technology for Drosophila melanogaster using germline-specific Cas9. PNAS. PMID: 24191015.
 * 8) Vinayagam, A., Zirin, J., Roesel, C., Hu, Y., Yilmazel, B., Samsonova, A., Neumuller, R., Mohr, S. E. and Perrimon, N. (2013) Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nature Methods. doi:10.1038/nmeth.2733. PMID:24240319.
 * 9) Zirin, J., Nieuwenhuis, J. and Perrimon, N. (2013) Role of autophagy in glycogen breakdown and its relevance to Chloroquine myopathy. PLoS Biology. DOI: 10.1371/journal.pbio.1001708.


 * The list also contained character in the private use area. "...Wolfe, M. S. (2003) [?]g-Secretase/presenilin..." I have replaced with a gamma, also corrected the spelling of "Alzheimers"
 * All the best: Rich Farmbrough, 13:09, 21 December 2016 (UTC).