Talk:Nucleolus/Archive 1

Wiki Education Foundation-supported course assignment
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): LaurenReasor, Snhunter94. Peer reviewers: LaurenReasor.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 05:28, 17 January 2022 (UTC)

Untitled
As a college and high school teacher I find this article adequate. The basic structure of the nucleolus is described and anyone who wishes to know more can simply read further. The original writer may not have had English as a first language, but they were apparently well educated. (Brhebert (talk) 00:53, 29 August 2009 (UTC))

Super useful article, but "higher eukaryotes" means nothing, especially when yeast is not considered one. Just say animals or vertebrates or whatever group you actually mean.

I'm sure the Nucleolus has a membrane. This specifically states that it is a non-membrane bound structure...oh yeah and TONS of editing is needed. —Preceding unsigned comment added by 71.58.240.25 (talk) 00:53, 15 December 2008 (UTC)

Should the article be tagged for being essay-like? Dog poster  19:30, 22 November 2009 (UTC)

=== What is the main function of the nuclear membrane?

Is to keep everything running in order. It contains instruction for the cell that come from the parent cell witch there is no mom and dad but they reproduce by A-sexual reproduction. The nucleus also contains the cells DNA to keep everything inside of it and unwanted things outside it just like the cell membrane.

...

This page reads as though the author's first language wasn't English. Serious editing work needed for clarity and readability.

NonDucor 23:06, 2 April 2006 (UTC) Did some editing to correct vandalism.Also minor fixes (my fisrt language isn't english also :) )

Rename Page to Nucleolus-Biology
This page's title should change to nucleolus-biology and a page nucleolus-game theory should be created. ngeorgak 09:05, 12 November 2012 (UTC)

can someone please make this articale clearer to understand? —Preceding unsigned comment added by 90.192.227.34 (talk) 16:00, 8 December 2007 (UTC)

How does the RNA relate to the entire DNA structure?
This topic lacks context. Does part of the cell's DNA rearrange itself spacially so that the appropriate parts of the relevant chromosomes are located next to each other and form the nucleolus? Or is rDNA some completely different structure from the genomic DNA'''?

the nucleolus is important —Preceding unsigned comment added by 67.131.245.219 (talk) 19:25, 5 December 2007 (UTC)

Not an organelle?
I've read the nucleolus itself is not considered an organelle, but a region inside the nucleous with great production of RNAr. Another point is that it doesn't have a membrane, so it can't be really considered an organelle... —Preceding unsigned comment added by 189.20.237.53 (talk) 21:10, 3 April 2008 (UTC)

I have seen it referred to as a "sub-organelle" in literature. Bform (talk) 19:53, 13 July 2008 (UTC)

Nucleolar localization?
Any expert care to add info about nucleolar localization signals/sequences? I know there is some information in the literature, but I haven't read into it enough myself. Bform (talk) 19:53, 13 July 2008 (UTC)

An unregistered user writes:

I'm an unregistered user. Thought I'd bring this up anyway. The intro on the page reads:

The nucleolus (also called nucleole) is an organelle within the Nucleus in which the chromosomes, RNA (see transcription) are melted and denatured and the ribosome subunits are assembled. Since it does not have a membrane, it is not considered an organelle.

So either:

1) the first sentence should not include the supposed misfact that the nucleolus is an organelle,

or

2) the part that states it is not an organelle is entirely wrong.

Simplicity
This essay-like note shows no recognition or thought towards the slightly less educated schoolkids that use this page, and is very difficult to understand
 * Agree! Some sections would be quite difficult for people without a background of microbiology. --Edward130603 (talk) 01:14, 12 March 2009 (UTC)


 * Maybe the three components of the nucleolus could be described better here instead of just listing them? Dog  poster  17:04, 14 August 2009 (UTC)

Some errors
The article was good but flawed in several areas, such as describing RNA pol III as prokaryotic in many places. Also the article wandered a little too much into the post-transcriptional modification and such so I chiseled it down a little bit. Orlandoturner (talk) 05:02, 6 January 2010 (UTC)

Sections
I think the section on "Function and ribosome assembly" should have two subsections: "Factors required for biogenesis" and "Transcription". Dog poster  22:05, 26 February 2010 (UTC)

Cell Biology Review
The introductory paragraph of this article is very broad and short in length and could be more easily understood if there were more information or if it was explained more in depth. There is also no citation for the end statement of this paragraph so plagiarism could become an issue.

In the "History" section, there are also no citations for the whole paragraph so readers aren't able to see where that specific information came from. This section is also very short and only talks about a single study that was done on the nucleolus and not specifically how or when it was discovered.

I noticed that the "Structure" section has more citations but the wording is hard to understand for readers that are non-experts on this specific organelle. Also, the last section labeled "Sequestration of Proteins" had information that could had been stated in the previous paragraph instead of writing on a few sentences in a completely separate section or it could have used more information on that specific topic.

I checked a few of the citations and there was many that only included a single definition or a small and broad paragraph about the topic or a link to buy a book that the information is in. I feel like there should be a few more scholarly articles that are used and cited for this specific article to make it better. Snhunter94 (talk) 14:05, 29 September 2016 (UTC)
 * Thanks for your thorough review, Snhunter94. However, to address your first point, the lead section does not need any citations because it is a summary of the rest of the article. Graham 87 12:02, 30 September 2016 (UTC)

Student Review
As a student in a cell biology course, I found the weight of information presented in this article to be rather inconsistent. The introduction was fairly easy to understand, but a definition for signal recognition particles would be helpful to a reader who isn't well-versed in the subject. Also, there was mention of nucleolus malfunction leading to several human diseases, which were never elaborated on. There should be a citation for that statement. Addition of a section about diseases related to malfunction could be added. I think that descriptions of terms early on in the article would be more practical, especially for non-specialists, so that they can receive some general knowledge about the nucleolus before they continue on to more in-depth details.

The following section about the history of nucleoli is somewhat limited because it only discusses early studies of nucleoli. First, I think that the study by Birnstiel and Wallace should be in a separate paragraph, and more information should be included about it. Also, it would be helpful for more recent studies about to nucleoli and their functions--or at least about major breakthroughs--to be mentioned. When did we learn that the nucleolus is the site for ribosome synthesis?

The section on structure is where this article begins to include a great deal of technical jargon that would be quite difficult for many non-specialists to understand. Descriptions of terms like "bipartite organization" and "intergenic region" should be provided in order to allow an average reader to understand the article. There is also a weird transition between the sentence about nucleolar vacuoles and the mention that many species of plant nucleoli have high iron contents--why are these related? Should they be in separate paragraphs? I personally do not know, but if there is a connection between the two, it should be explained.

The discussion of function and ribosome assembly was quite overwhelming the first time that I looked at it. I think that for most people, the language used to describe the biogenesis of ribosomes is very technical and difficult to understand, and the density of acronyms makes it easy to lose track of what is being stated. While all this information may be accurate, I think that a more general explanation should be given prior to the in-depth, technical description. Also, figures that demonstrate the process may aid readers in trying to understand the processes described. It may make more sense to make a complete separate section about ribosome biogenesis and to make the initial paragraph about nucleolus location and its relationship with DNA a separate section.

The final section on protein sequestration is also a little technical and in need of a more basic description.

I think that a student entering biology courses would likely not understand most of the processes described in this article. In general, I think that it just needs a lot more background information with basic descriptions so that the majority of readers will understand it. With that addition, the technical information would be much more informative. LaurenReasor (talk) 20:48, 30 September 2016 (UTC)Reasor

removal of uncited sentence starting with "The DFC consists of ..."
Hello. As you may have noticed already, I'm upgrading this article. The sentence "The DFC consists of newly transcribed rRNA bound to ribosomal proteins, while the GC contains RNA bound to ribosomal proteins that are being assembled into immature ribosomes." has no citation and is too specific from my knowledge. I'll be removing it and replacing it. JeanOhm (talk) 21:54, 18 June 2017 (UTC)

Fixing the image
As far as I'm aware, there are no ribosomes on the membrane of the nucleolus. I would be glad to be shown a source for this claim. To the best of my knowledge, no translation occurs in the nucleus at all, not to mention the nucleolus. — Preceding unsigned comment added by Brolulu (talk • contribs) 20:00, 25 May 2021 (UTC)


 * The nucleolus does not have a membrane. If you're referring to the first image, it's of a nucleus (including the nucleolus inside it). The ribosomes are shown on the outside of the nucleus's membrane. --R. S. Shaw (talk) 02:41, 26 May 2021 (UTC)


 * My bad, I missed that.  Brolulu (talk) 16:56, 27 May 2021 (UTC)