Talk:Pentadecylic acid

Chembox
Could add chembox as done by Heptadecanoic acid Rod57 (talk) 12:35, 31 August 2010 (UTC)
 * ✅ -- Ed (Edgar181) 13:15, 2 September 2010 (UTC)

"Pentadecenoic" listed at Redirects for discussion
A discussion is taking place to address the redirect Pentadecenoic. The discussion will occur at Redirects for discussion/Log/2020 October 19 until a consensus is reached, and readers of this page are welcome to contribute to the discussion. Mdewman6 (talk) 19:35, 19 October 2020 (UTC)

Relationship to dairy fat and CVD risk
Pentadecanoic acid is a poor biomarker of dairy fat as it is present in dairy fat at only 1.0% or less. Rapeseed oil (canola) contains both pentadecanoic acid and heptadecanoic acid, and cabbage and cucumbers also contain pentadecanoic acid in small amounts. With this one can find any food with a tiny amount of pentadecanoic acid (under 1%) and then try and link it to lower CVD risk. It is unlikely pentadecanoic acid has any effect at this trace level. It is not like palmitic acid or other saturated fatty acids that are present in foods at 20%, 30% or 40%+ which have been shown to have an effect on CVD risk.

Claiming pentadecylic acid will bring about a reduction in CVD is not supported by strong evidence. The review paper cited admits that "Study limitations include the inability of the biomarkers to distinguish different types of dairy foods and that most studies in the meta-analyses (including our novel cohort study) only assessed biomarkers at baseline, which may increase the risk of misclassification of exposure levels." 

It seems the above review paper is being cited on social media platforms by the low-carb community who are claiming it refutes dietary guidelines that are telling people to limit dairy fat consumption. However, this is very weak evidence. It does not overturn dietary guidelines. Psychologist Guy (talk) 17:46, 18 April 2023 (UTC)
 * If you know the area and see something misleading in the article, please remove the content! That kind of correction happens frequently.  If you think that the sentence is an over statement, then you can rephrase the section such as "It has been claimed that ....", thus alerting readers.  The very best response is to cite a more authoritative source. The main thing is to act.--Smokefoot (talk) 19:15, 18 April 2023 (UTC)
 * After Psychologist Guy's useful edits, the article has the balance of removing potential hype from preliminary research, adhering to existing dietary guidelines, and yet citing two reviews of biomarker evidence. The Imamura and Trieu publications were multinational studies involving biomarker experts, so carry some weight, but those reviews were on preliminary dietary studies, leading to a conclusion of weak evidence. With this edit, we can further state balance that "In reviews of preliminary dietary research, higher circulating concentrations of pentadecyclic acid were associated with a lower risk...". Zefr (talk) 20:12, 18 April 2023 (UTC)
 * I agree with you that pentadecanoic acid isn't a useful biomarker for dairy. It is for fiber, however. Most serum pentadecanoic and heptadecanoic acid is created by gut biota chowing down on fiber.
 * I think the evidence of the health benefits are pretty compelling. I just think the benefits come from consuming fiber, not dairy. 2600:1700:83E0:736F:CD76:B0EE:15F7:EAF (talk) 03:09, 18 June 2024 (UTC)